(Q35206850)

7 August 2017

Toll-like receptor 4-mediated signaling by epithelial surfaces: necessity or threat? (English)

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7 August 2017

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Fredrik Bäckhed

1

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author name string

Mathias Hornef

series ordinal

2

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7 August 2017

1 September 2003

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7 August 2017

Microbes and Infection

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7 August 2017

5

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7 August 2017

951-959

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7 August 2017

11

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Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase.

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Antibacterial and anti-inflammatory agents that target endotoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Genetic Control of Leucocyte Responses to Endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

A family of human receptors structurally related to Drosophila Toll

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

TLR6: A novel member of an expanding toll-like receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Wanted: a molecular basis for specificity in toll-like receptor signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Human keratinocytes express functional CD14 and toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Microbial ecology of the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Strategic compartmentalization of Toll-like receptor 4 in the mouse gut

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

How host-microbial interactions shape the nutrient environment of the mammalian intestine

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Structural characterization of the lipid A component of Bacteroides fragilis strain NCTC 9343 lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

E5531, a pure endotoxin antagonist of high potency

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Deacylated lipopolysaccharide inhibits neutrophil adherence to endothelium induced by lipopolysaccharide in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Commensal host-bacterial relationships in the gut

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

The 'innate' host response protects and damages the infected urinary tract.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

The management of urinary infections; what have we learned in the past decade?

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Virulence factors in Escherichia coli urinary tract infection

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

P fimbriae-dependent, lipopolysaccharide-independent activation of epithelial cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Type 1 fimbriae deliver an LPS- and TLR4-dependent activation signal to CD14-negative cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

IFNs activate toll-like receptor gene expression in viral infections

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Priming of human oral epithelial cells by interferon-gamma to secrete cytokines in response to lipopolysaccharides, lipoteichoic acids and peptidoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Lipopolysaccharide modulation of normal enterocyte turnover by toll-like receptors is mediated by endogenously produced tumour necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Contrasting responses of human gingival and colonic epithelial cells to lipopolysaccharides, lipoteichoic acids and peptidoglycans in the presence of soluble CD14.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Bacterial fimbriae and their peptides activate human gingival epithelial cells through Toll-like receptor 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Differences in LPS-induced activation of bronchial epithelial cells (BEAS-2B) and type II-like pneumocytes (A-549).

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Type I Helicobacter pylori lipopolysaccharide stimulates toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Distinct mechanism of Helicobacter pylori-mediated NF-kappa B activation between gastric cancer cells and monocytic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

Nuclear factor-kappa B directs carcinoembryonic antigen-related cellular adhesion molecule 1 receptor expression in Neisseria gonorrhoeae-infected epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2803%2900189-8

7 January 2021

10.1016/S1286-4579(03)00189-8

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12941387