(Q35206936)

7 August 2017

1 reference

title

Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm (English)

1 reference

7 August 2017

Hugh Rosen

1

1 reference

PubMed ID

12941420

7 August 2017

Jiayu Liao

series ordinal

2

1 reference

7 August 2017

1 August 2003

1 reference

Current Opinion in Chemical Biology

7 August 2017

1 reference

7 August 2017

7

1 reference

7 August 2017

461-468

1 reference

7 August 2017

4

1 reference

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

The therapeutic potential of modulating the ceramide/sphingomyelin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate as a therapeutic agent

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine-1-phosphate: an enigmatic signalling lipid

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Subtype-specific differential regulation of Rho family G proteins and cell migration by the Edg family sphingosine-1-phosphate receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Lipid mediators of angiogenesis and the signalling pathways they initiate

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Cell type-specific localization of human cardiac S1P receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate and control of vascular tone

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Egress: a receptor-regulated step in lymphocyte trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Molecular basis for lysophosphatidic acid receptor antagonist selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

RETRACTED: Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine-1-phosphate receptors and the development of the vascular system

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Immunosuppressant FTY720 inhibits thymocyte emigration

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY720, a novel immunosuppressant, induces sequestration of circulating lymphocytes by acceleration of lymphocyte homing

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Effect of FTY720, a novel immunosuppressant, on adjuvant- and collagen-induced arthritis in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY 720A mediates reduction of lymphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Enzymes of sphingosine metabolism as potential pharmacological targets for therapeutic intervention in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Ceramide enables fas to cap and kill.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Ceramide-coated balloon catheters limit neointimal hyperplasia after stretch injury in carotid arteries

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

T-cell apoptosis triggered by FTY720 via mitochondrial pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells).

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

Evidence that FTY720 induces T cell apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900085-1

7 January 2021

10.1016/S1367-5931(03)00085-1

Identifiers

DOI

1 reference

7 August 2017

1 reference

PubMed ID

12941420