(Q35222785)

7 August 2017

title

Increased fibroblast growth factor 21 expression in high-fat diet-sensitive non-human primates (Macaca mulatta). (English)

1 reference

7 August 2017

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E B Nygaard

1

1 reference

7 August 2017

C L Møller

2

1 reference

7 August 2017

P Kievit

3

1 reference

7 August 2017

K L Grove

4

1 reference

7 August 2017

B Andersen

5

1 reference

7 August 2017

language of work or name

English

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publication date

21 May 2013

1 reference

International Journal of Obesity

7 August 2017

published in

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7 August 2017

volume

38

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7 August 2017

issue

2

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7 August 2017

page(s)

183-191

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The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

7 August 2017

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27 July 2018

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Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism

27 July 2018

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Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.

27 July 2018

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

27 July 2018

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Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?

27 July 2018

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The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21.

27 July 2018

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Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

27 July 2018

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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

27 July 2018

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27 July 2018

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Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease

27 July 2018

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Fibroblast growth factor-21 is induced in human skeletal muscles by hyperinsulinemia

27 July 2018

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Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects

27 July 2018

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FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

27 July 2018

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FGF21 is an Akt-regulated myokine

27 July 2018

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Fibroblast growth factor 21 corrects obesity in mice

27 July 2018

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27 July 2018

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Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

27 July 2018

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betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

27 July 2018

1 reference

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Functional evolutionary history of the mouse Fgf gene family

27 July 2018

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Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes

27 July 2018

1 reference

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PPARalpha is a key regulator of hepatic FGF21.

27 July 2018

1 reference

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Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

27 July 2018

1 reference

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Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

27 July 2018

1 reference

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BetaKlotho is required for metabolic activity of fibroblast growth factor 21

27 July 2018

1 reference

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Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

27 July 2018

1 reference

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The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

27 July 2018

1 reference

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Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

27 July 2018

1 reference

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FGF-21 as a novel metabolic regulator

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)alpha activator, in non-human primates

27 July 2018

1 reference

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Identification of a novel FGF, FGF-21, preferentially expressed in the liver

27 July 2018

1 reference

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Primer3 on the WWW for general users and for biologist programmers

27 July 2018

1 reference

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Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Impact of short-term high-fat feeding and insulin-stimulated FGF21 levels in subjects with low birth weight and controls

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Understanding the physical interactions in the FGF21/FGFR/β-Klotho complex: structural requirements and implications in FGF21 signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Serum fibroblast growth factor 21 is associated with adverse lipid profiles and gamma-glutamyltransferase but not insulin sensitivity in Chinese subjects

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Plasma FGF-21 levels in type 2 diabetic patients with ketosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

Effects of fenofibrate on lipid parameters in obese rhesus monkeys

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376022

26 September 2018

Identifiers

DOI

10.1038/IJO.2013.79

1 reference

7 August 2017

1 reference

7 August 2017

1 reference