(Q35340158)

7 August 2017

title

A GCase chaperone improves motor function in a mouse model of synucleinopathy (English)

1 reference

Marie-Françoise Chesselet

7 August 2017

0 references

1 reference

18

object named as

Marie-Françoise Chesselet

1 reference

7 August 2017

Franziska Richter

1

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7 August 2017

Sheila M Fleming

2

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7 August 2017

Melanie Watson

3

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7 August 2017

Vincent Lemesre

4

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7 August 2017

Lee Pellegrino

5

1 reference

7 August 2017

Brian Ranes

6

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7 August 2017

Chunni Zhu

7

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7 August 2017

Farzad Mortazavi

8

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7 August 2017

Caitlin K Mulligan

9

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7 August 2017

Pedrom C Sioshansi

10

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7 August 2017

Sindalana Hean

11

1 reference

7 August 2017

Krystal De La Rosa

12

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7 August 2017

Richie Khanna

13

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7 August 2017

John Flanagan

14

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7 August 2017

David J Lockhart

15

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7 August 2017

Brandon A Wustman

16

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7 August 2017

Sean W Clark

17

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7 August 2017

publication date

1 October 2014

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7 August 2017

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7 August 2017

volume

11

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7 August 2017

issue

4

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7 August 2017

page(s)

840-856

1 reference

describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4391384/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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27 July 2018

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Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies

27 July 2018

1 reference

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Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.

27 July 2018

1 reference

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Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

27 July 2018

1 reference

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Ex vivo and in vivo effects of isofagomine on acid β-glucosidase variants and substrate levels in Gaucher disease

27 July 2018

1 reference

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27 July 2018

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27 July 2018

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CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

27 July 2018

1 reference

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27 July 2018

1 reference

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Alpha-synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases

27 July 2018

1 reference

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Identification and characterization of pharmacological chaperones to correct enzyme deficiencies in lysosomal storage disorders

27 July 2018

1 reference

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Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model

27 July 2018

1 reference

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Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein

27 July 2018

1 reference

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A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions

27 July 2018

1 reference

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Genetic Analysis of Pathways to Parkinson Disease

27 July 2018

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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

27 July 2018

1 reference

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The risk of Parkinson's disease in type 1 Gaucher disease

27 July 2018

1 reference

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Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway

27 July 2018

1 reference

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27 July 2018

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Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein

27 July 2018

1 reference

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Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein

27 July 2018

1 reference

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Olfactory deficits in mice overexpressing human wildtype alpha-synuclein

27 July 2018

1 reference

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Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression

27 July 2018

1 reference

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27 July 2018

1 reference

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Parkinson's disease and related alpha-synucleinopathies are brain amyloidoses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

27 July 2018

1 reference

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Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor

27 July 2018

1 reference

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Contribution of somal Lewy bodies to neuronal death

27 July 2018

1 reference

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Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of beta-glucosidase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

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26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Chemical chaperones and permissive temperatures alter localization of Gaucher disease associated glucocerebrosidase variants

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

The iminosugar isofagomine increases the activity of N370S mutant acid beta-glucosidase in Gaucher fibroblasts by several mechanisms

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4391384

A feedforward loop links Gaucher and Parkinson's diseases?

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25037721

12 December 2020

inferred from PubMed ID database lookup

ER retention and degradation as the molecular basis underlying Gaucher disease heterogeneity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25037721

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S13311-014-0294-X

1 reference

release_3fcwu5yjifgjvciwmpu2ydzvtu

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3fcwu5yjifgjvciwmpu2ydzvtu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4391384

1 reference

7 August 2017

1 reference