(Q35557641)

English

The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.

scientific article published on October 2003

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scholarly article

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20 December 2019

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The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis (English)

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20 December 2019

apoptotic process

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inferred from title

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20 December 2019

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Susan K Gillespie

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20 December 2019

Jodie M Borrow

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20 December 2019

Peter Hersey

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1 October 2003

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20 December 2019

Biochemical Pharmacology

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20 December 2019

66

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20 December 2019

1537-1545

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20 December 2019

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20 December 2019

On the biological role of histone acetylation

1 reference

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7 January 2021

Translating the Histone Code

1 reference

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7 January 2021

Histone acetylation in chromatin structure and transcription

1 reference

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7 January 2021

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

1 reference

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7 January 2021

Histone acetylases and deacetylases in cell proliferation

1 reference

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7 January 2021

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

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The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth

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7 January 2021

Mutations truncating the EP300 acetylase in human cancers

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

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A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

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7 January 2021

p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

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7 January 2021

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

1 reference

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7 January 2021

Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis

1 reference

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7 January 2021

Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells

1 reference

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7 January 2021

Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts.

1 reference

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7 January 2021

bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis

1 reference

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7 January 2021

Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma

1 reference

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7 January 2021

Phenylbutyrate attenuates the expression of Bcl-X(L), DNA-PK, caveolin-1, and VEGF in prostate cancer cells

1 reference

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7 January 2021

Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts

1 reference

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7 January 2021

Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate

1 reference

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7 January 2021

Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

1 reference

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7 January 2021

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

1 reference

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7 January 2021

Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

1 reference

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7 January 2021

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

1 reference

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7 January 2021

IGF-II enhances trichostatin A-induced TGFbeta1 and p21(Waf1,Cip1, sdi1) expression in Hep3B cells.

1 reference

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7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

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7 January 2021

TRAIL: a molecule with multiple receptors and control mechanisms

1 reference

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7 January 2021

How melanoma cells evade trail-induced apoptosis.

1 reference

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7 January 2021

The CARD domain: a new apoptotic signalling motif

1 reference

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7 January 2021

TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900509-4

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

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7 January 2021

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

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7 January 2021

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

1 reference

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7 January 2021

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

1 reference

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7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

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7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

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7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

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7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

1 reference

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

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7 January 2021

c-MYC: more than just a matter of life and death

1 reference

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7 January 2021

Myc potentiates apoptosis by stimulating Bax activity at the mitochondria

1 reference

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7 January 2021

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

1 reference

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

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7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

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7 January 2021

Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules

1 reference

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7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

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7 January 2021

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

1 reference

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7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

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7 January 2021

A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function

1 reference

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7 January 2021

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

1 reference

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7 January 2021

Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells

1 reference

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7 January 2021

Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis

1 reference

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7 January 2021

The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation.

1 reference

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7 January 2021

Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria

1 reference

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7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

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7 January 2021

Methylation-induced repression--belts, braces, and chromatin

1 reference

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7 January 2021

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

1 reference

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7 January 2021

Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling

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7 January 2021

Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis

1 reference

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7 January 2021

Identifiers

10.1016/S0006-2952(03)00509-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14555232%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14555232%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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