Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35561587)
Watch
English
The CD95 type I/type II model
scientific article published on June 2003
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The CD95 type I/type II model
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
author
Marcus E. Peter
object named as
Marcus E Peter
series ordinal
3
0 references
author name string
Bryan C Barnhart
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
Elizabeth C Alappat
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
published in
Seminars in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
volume
15
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
page(s)
185-193
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
cites work
The biochemistry of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosome: the seven-spoked death machine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two CD95 (APO-1/Fas) signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences between CD95 type I and II cells detected with the CD95 ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 does not inhibit cell death induced by the physiological Fas ligand: implications for the existence of type I and type II cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirement for caspase 9 in apoptotic pathways in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of mitochondrial apoptosis-inducing factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endonuclease G is an apoptotic DNase when released from mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular ordering of the initial signaling events of CD95.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Downregulation of Fas ligand by shedding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3'-kinase blocks CD95 aggregation and caspase-8 cleavage at the death-inducing signaling complex by modulating lateral diffusion of CD95
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation and characterization of Smac/DIABLO-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of protein kinase C attenuates early signals in Fas-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the protein kinase C pathway promotes anti-CD95-induced apoptosis in Jurkat T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the functional soluble form of human fas ligand in activated lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas ligand in human serum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 oncoprotein protects the human prostatic carcinoma cell line PC3 from TRAIL-mediated apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor receptor and Fas signaling mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1044-5323(03)00031-9
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
PubMed ID
14563117
1 reference
stated in
Europe PubMed Central
PubMed ID
14563117
retrieved
8 August 2017
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit