(Q35577920)

9 August 2017

1 reference

title

The immune response of Drosophila (English)

1 reference

9 August 2017

0 references

innate immune response

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14603309

29 March 2024

author name string

Jules A. Hoffmann

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14603309

29 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

9 August 2017

6 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14603309

full work available at URL

29 March 2024

http://www.nature.com/articles/nature02021.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NATURE02021

http://www.nature.com/articles/nature02021

29 March 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE02021

29 March 2024

1 reference

9 August 2017

426

1 reference

9 August 2017

33-38

1 reference

9 August 2017

6962

1 reference

https://scigraph.springernature.com/pub.10.1038/nature02021

9 August 2017

0 references

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Innate immune recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Selective destruction of a host blood cell type by a parasitoid wasp

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Drosophila innate immunity: an evolutionary perspective

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Antimicrobial peptides in insects; structure and function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

kappa B-like motifs regulate the induction of immune genes in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The origin of pattern and polarity in the Drosophila embryo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A conserved signaling pathway: the Drosophila toll-dorsal pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A family of human receptors structurally related to Drosophila Toll

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Getting knotted: a model for the structure and activation of Spätzle.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Proteolytic processing of the Drosophila Spätzle protein by easter generates a dimeric NGF-like molecule with ventralising activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Drosophila MyD88 is an adapter in the Toll signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A heterotrimeric death domain complex in Toll signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Dif, a dorsal-related gene that mediates an immune response in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A genome-wide analysis of immune responses in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Tissue and stage-specific expression of the Tolls in Drosophila embryos.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A family of proteins related to Spätzle, the toll receptor ligand, are encoded in the Drosophila genome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila membrane receptor Toll can function to promote cellular adhesion.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Relish, a central factor in the control of humoral but not cellular immunity in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Role of Drosophila IKK gamma in a toll-independent antibacterial immune response.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Interactions between the cellular and humoral immune responses in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Caspase-mediated processing of the Drosophila NF-kappaB factor Relish

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Sequential activation of signaling pathways during innate immune responses in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Toll and Imd pathways are the major regulators of the immune response in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A peptidoglycan recognition protein in innate immunity conserved from insects to humans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A pattern recognition protein for peptidoglycan. Cloning the cDNA and the gene of the silkworm, Bombyx mori

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A pattern-recognition protein for beta-1,3-glucan. The binding domain and the cDNA cloning of beta-1,3-glucan recognition protein from the silkworm, Bombyx mori

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Activation of Drosophila Toll during fungal infection by a blood serine protease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

A scavenger function for a Drosophila peptidoglycan recognition protein.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

The Drosophila immune system detects bacteria through specific peptidoglycan recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02021

7 January 2021

Identifiers

DOI

10.1038/NATURE02021

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference