(Q35589761)

9 August 2017

1 reference

title

Separation and detection methods for covalent drug-protein adducts (English)

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9 August 2017

Shufeng Zhou

1

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9 August 2017

1 November 2003

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Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences

9 August 2017

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9 August 2017

797

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9 August 2017

63-90

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9 August 2017

1-2

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The relevance of chemico-biological interactions for the toxic and carcinogenic effects of aromatic amines. V. The pharmacokinetics of related aromatic amines in blood

9 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The immunologic and metabolic basis of drug hypersensitivities

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Evaluation of genetic risks of alkylating agents. II. Haemoglobin as a dose monitor

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Protein targets of xenobiotic reactive intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Protein adducts: quantitative and qualitative aspects of their formation, analysis and applications

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

On the diversity of oxidative bioactivation reactions on nitrogen-containing xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Enzymatic activation of chemicals to toxic metabolites.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolic activation of toxins: tissue-specific expression and metabolism in target organs

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human CYPs: in vivo and clinical aspects

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Summary of information on human CYP enzymes: human P450 metabolism data

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

N-oxidative transformation of free and N-substituted amine functions by cytochrome P450 as means of bioactivation and detoxication

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug metabolism by leukocytes and its role in drug-induced lupus and other idiosyncratic drug reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

1 reference

7 January 2021

N-chlorination of phenytoin by myeloperoxidase to a reactive metabolite

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolism of phenytoin and covalent binding of reactive intermediates in activated human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The effects of nitric oxide on the oxidations of l-dopa and dopamine mediated by tyrosinase and peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Structural features associated with reactive metabolite formation in clozapine analogues

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

N-Chlorination and oxidation of procainamide by myeloperoxidase: toxicological implications

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Oxidation of diclofenac to reactive intermediates by neutrophils, myeloperoxidase, and hypochlorous acid

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Hepatic disposition of electrophilic acyl glucuronide conjugates.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Sulfotransferases in the bioactivation of xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification and reactivity of the major metabolite (beta-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Acyl glucuronide drug metabolites: toxicological and analytical implications

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Sulfotransferases: genetics and role in toxicology

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanisms of hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drugs and the liver: advances in metabolism, toxicity, and therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

1 reference

7 January 2021

Drug-induced liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug-induced liver disorders: implications for drug development and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Extrahepatic metabolism of drugs in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The structure and function of the UDP-glucuronosyltransferase gene family

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Reactive intermediates in biological systems: what have we learned and where are we going?

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Resolution of human mercapt- and nonmercaptalbumin by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Detection and identification of protein variants and adducts in blood and tissues: an application of soft ionization mass spectrometry to clinical diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Monitoring of environmental cancer initiators through hemoglobin adducts by a modified Edman degradation method

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Influence of tertiary structure on nucleophilic substitution reactions of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent binding of xenobiotics to specific proteins in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification and quantification of in vitro adduct formation between protein reactive xenobiotics and a lysine-containing model peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Observation of covalent intermediates in an enzyme mechanism at atomic resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Hepatotoxicity of commonly used drugs: nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Selective protein covalent binding and target organ toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanism of idiosyncratic drug reactions: reactive metabolite formation, protein binding and the regulation of the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug-induced immunotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Use of covalent binding in risk assessment.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Carcinogen macromolecular adducts and their measurement

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mercapturic acids, protein adducts, and DNA adducts as biomarkers of electrophilic chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Proteomic approaches to characterize protein modifications: new tools to study the effects of environmental exposures

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Monitoring 2-D gel-induced modifications of proteins by MALDI-TOF mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immunochemical detection of acetaminophen-bound liver proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phosphatidylinositol-specific phospholipase C-alpha but has no activity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

cDNA cloning and baculovirus expression of the human liver endoplasmic reticulum P58: characterization as a protein disulfide isomerase isoform, but not as a protease or a carnitine acyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Serum antibodies from halothane hepatitis patients react with the rat endoplasmic reticulum protein ERp72.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Autoantibodies to hepatic microsomal carboxylesterase in halothane hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Glutathione-S-transferase is a target for covalent modification by a halothane reactive intermediate in the guinea pig liver.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Characterisation of proteins from two-dimensional electrophoresis gels by matrix-assisted laser desorption mass spectrometry and amino acid compositional analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Improvement of in-gel digestion protocol for peptide mass fingerprinting by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Sequence mapping of epoxide adducts in human hemoglobin with LC-tandem MS and the SALSA algorithm

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of mouse liver proteins on two-dimensional electrophoresis gels by matrix-assisted laser desorption/ionization mass spectrometry of in situ enzymatic digests

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

High-performance affinity chromatography and immobilized serum albumin as probes for drug- and hormone-protein binding

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Post-translational non-enzymatic modification of proteins. II. Separation of selected protein species after glycation and other carbonyl-mediated modifications

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

High-performance cation-exchange chromatography of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mobile phase selection for the high-performance ion-exchange chromatography of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Kinetic analysis of the covalent binding of captopril to human serum albumin

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Inhibition of tubulin assembly and covalent binding to microtubular protein by valproic acid glucuronide in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Synthesis and characterization of a penicillin-poly(L-lysine) which recognizes human IgE anti-penicillin antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Toward an in Vitro Test for the Diagnosis of Allergy to Penicillins. Synthesis, Characterization, and Use of β-Lactam and β-Lactam Metabolite Poly-l-lysines Which Recognize Human IgE Antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Electrospray low energy CID and MALDI PSD fragmentations of protonated sulfinamide cross-linked peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Gemfibrozil and its oxidative metabolites: quantification of aglycones, acyl glucuronides, and covalent adducts in samples from preclinical and clinical kinetic studies

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

In vitro regioselective stability of beta-1-O- and 2-O-acyl glucuronides of naproxen and their covalent binding to human serum albumin

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Determination of the covalent adducts of the novel anti-cancer agent 5,6-dimethylxanthenone-4-acetic acid in biological samples by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent binding of suprofen acyl glucuronide to albumin in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Glycation of human serum albumin by acylglucuronides of nonsteroidal anti-inflammatory drugs of the series of phenylpropionates

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Structural characterization of the major covalent adduct formed in vitro between acetaminophen and bovine serum albumin

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immunochemical detection of drug-protein adducts in acetaminophen hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Evidence suggesting the 58-kDa acetaminophen binding protein is a preferential target for acetaminophen electrophile

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immunochemical detection and identification of protein adducts of diclofenac in the small intestine of rats: possible role in allergic reactions.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2)

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The current state of two-dimensional electrophoresis with immobilized pH gradients

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Two-dimensional gel electrophoresis: recent advances in sample preparation, detection and quantitation

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

An evaluation of the use of two-dimensional gel electrophoresis in proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent protein modifications and gene expression changes in rodent liver following administration of methapyrilene: a study using two-dimensional electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The hepatocarcinogen methapyrilene but not the analog pyrilamine induces sustained hepatocellular replication and protein alterations in F344 rats in a 13-week feed study

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Comparisons of protein changes in human and rodent hepatocytes induced by the rat-specific carcinogen, methapyrilene.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Stationary phases for capillary electrophoresis and capillary electrochromatography

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Protein analysis by capillary zone electrophoresis utilizing a trifunctional diamine for silica coating.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Microchip-based capillary electrophoresis of human serum proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of DNA adducts by capillary methods coupled to mass spectrometry: a perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

DNA adduct research with capillary electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of peptides and proteins by capillary electrophoresis/mass spectrometry using acidic buffers and coated capillaries

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of peptides, proteins, protein digests, and whole human blood by capillary electrophoresis/electrospray ionization-mass spectrometry using an in-capillary electrode sheathless interface

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Sheathless capillary electrophoresis-electrospray ionization mass spectrometry using 10 μm I.D. capillaries: Analyses of tryptic digests of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Capillary electrophoresis of peptides and proteins in isoelectric buffers: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Collection of alpha1-acid glycoprotein molecular species by capillary electrophoresis and the analysis of their molecular masses and carbohydrate chains. Basic studies on the analysis of glycoprotein glycoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of hemoglobin and globin chain variants by a commonly used capillary isoelectric focusing method

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of recombinant and modified proteins by capillary zone electrophoresis coupled with electrospray ionization tandem mass spectrometry

1 reference

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7 January 2021

Albumin adducts in plasma from workers exposed to toluene diisocyanate

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7 January 2021

Mass spectrometry of peptides and proteins

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7 January 2021

Early discovery drug screening using mass spectrometry

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7 January 2021

Identification and characterization of posttranslational modifications of proteins by MALDI ion trap mass spectrometry

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7 January 2021

The coming of age of mass spectrometry in peptide and protein chemistry

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7 January 2021

On the evaporation of small ions from charged droplets

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7 January 2021

A brief overview of the present status of the mechanisms involved in electrospray mass spectrometry

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7 January 2021

Characterization of covalent adducts to intact cytochrome P450s by mass spectrometry

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7 January 2021

Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs.

1 reference

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7 January 2021

A novel approach for identification and measurement of hemoglobin adducts with 1,2,3,4-diepoxybutane by liquid chromatography/electrospray ionisation mass spectrometry and matrix-assisted laser desorption/ionisation tandem mass spectrometry

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7 January 2021

A new approach for measuring protein adducts from benzo[a]pyrene diolepoxide by high performance liquid chromatography/tandem mass spectrometry

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7 January 2021

Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac

1 reference

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7 January 2021

Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin

1 reference

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7 January 2021

Four decades of structure determination by mass spectrometry: from alkaloids to heparin

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7 January 2021

Protein sequencing by tandem mass spectrometry

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7 January 2021

Tandem mass spectrometric characterization of modified peptides and proteins

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7 January 2021

Synthesis and mass-spectrometric characterization of human serum albumins modified by covalent binding of two non-steroidal anti-inflammatory drugs: tolmetin and zomepirac

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7 January 2021

Epoxide adducts to N-terminal valine of hemoglobin

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7 January 2021

Tobacco-specific nitrosamine-hemoglobin adducts

1 reference

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7 January 2021

Gas chromatography-mass spectrometry determination of ethylenethiourea hemoglobin adducts: a possible indicator of exposure to ethylene bis dithiocarbamate pesticides.

1 reference

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7 January 2021

Dose-dependent protein adduct formation in kidney, liver, and blood of rats and in human blood after perchloroethene inhalation

1 reference

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7 January 2021

Analysis of DNA and protein adducts of benzo[a]pyrene in human tissues using structure-specific methods

1 reference

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7 January 2021

Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats

1 reference

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7 January 2021

Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins

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7 January 2021

Quantitative analysis of alachlor protein adducts by gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

2,6-Dimethylaniline--hemoglobin adducts from lidocaine in humans.

1 reference

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7 January 2021

Coupling capillary zone electrophoresis and continuous-flow fast atom bombardment mass spectrometry for the analysis of peptide mixtures

1 reference

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7 January 2021

Structural characterization of chondroitin/dermatan sulfate oligosaccharides from bovine aorta by capillary electrophoresis and electrospray ionization quadrupole time-of-flight tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Detection of modified peptides in enzymatic digests by capillary liquid chromatography/electrospray mass spectrometry and a programmable skimmer CID acquisition routine

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Analysis of DNA adducts using high-performance separation techniques coupled to electrospray ionization mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Capillary electrochromatography-mass spectrometry for the separation and identification of isomeric polyaromatic hydrocarbon DNA adducts derived from in vitro reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Detection and identification of benzo[a]pyrene diol epoxide adducts to DNA utilizing capillary electrophoresis-electrospray mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

NMR in drug discovery

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Theoretical and computational advances in biomolecular NMR spectroscopy

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7 January 2021

Covalent enzyme-substrate compounds: detection and catalytic competence

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7 January 2021

Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Multiple hyphenation of liquid chromatography with nuclear magnetic resonance spectroscopy, mass spectrometry and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography–mass spectrometry–nuclear magnetic resonance spectroscopy

1 reference

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7 January 2021

High-performance liquid chromatography/NMR spectrometry/mass spectrometry: further advances in hyphenated technology

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

p-Nitrosophenetole: a reactive intermediate of phenacetin that binds to protein

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Rapid internal acyl migration and protein binding of synthetic probenecid glucuronides

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug-specific antibodies in patients receiving captopril

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

An immunological method for the detection of captopril-protein conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Opposite Behaviors of Reactive Metabolites of Tienilic Acid and Its Isomer toward Liver Proteins: Use of Specific Anti-Tienilic Acid−Protein Adduct Antibodies and the Possible Relationship with Different Hepatotoxic Effects of the Two Compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Inhibition and possible induction of rat CYP2D after short- and long-term treatment with antidepressants

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Inhibition of microsomal cytochromes P450 in rat liver by the tricyclic antidepressant drug desipramine and its primary oxidized metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Characterization of drug-protein interactions by classic methods

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Drug-protein binding sites. New trends in analytical and experimental methodology

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Non-invasive radiotracer imaging as a tool for drug development

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolite analysis, isolation and purity assessment using various liquid chromatographic techniques combined with radioactivity detection

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The covalent binding of [14C]acetaminophen to mouse hepatic microsomal proteins: the specific binding to calreticulin and the two forms of the thiol:protein disulfide oxidoreductases

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent binding of acetaminophen to mouse hemoglobin. Identification of major and minor adducts formed in vivo and implications for the nature of the arylating metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolic activation of the antidepressant tianeptine. I. Cytochrome P-450-mediated in vitro covalent binding

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Occurrence of autoantibody to protein disulfide isomerase in rats with xenobiotic-induced hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Quantitative analysis of aflatoxin-albumin adducts

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanism of action of acetaminophen: is there a cyclooxygenase 3?

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanisms of acetaminophen toxicity: immunochemical detection of drug-protein adducts.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Acetaminophen-induced hepatotoxicity

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Over-the-counter analgesics: a toxicology perspective

1 reference

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7 January 2021

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Selective protein arylation and acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of the mouse liver 44-kDa acetaminophen-binding protein as a subunit of glutamine synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Glutamate dehydrogenase covalently binds to a reactive metabolite of acetaminophen

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Two-dimensional electrophoresis of membrane proteins: a current challenge for immobilized pH gradients

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver

1 reference

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7 January 2021

Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Pharmacology of systemic analgesics

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The second generation of COX-2 inhibitors: what advantages do the newest offer?

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Sensitivity to nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Studies on the reactivity of acyl glucuronides--VI. Modulation of reversible and covalent interaction of diflunisal acyl glucuronide and its isomers with human plasma protein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Studies on the reactivity of acyl glucuronides--VIII. Generation of an antiserum for the detection of diflunisal-modified proteins in diflunisal-dosed rats

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Idiosyncratic liver toxicity of nonsteroidal antiinflammatory drugs: molecular mechanisms and pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Multiple mechanisms in indomethacin-induced impairment of hepatic cytochrome P450 enzymes in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Enflurane metabolism produces covalently bound liver adducts recognized by antibodies from patients with halothane hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Halogenated anesthetics form liver adducts and antigens that cross-react with halothane-induced antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolic activation of the tricyclic antidepressant amineptine--I. Cytochrome P-450-mediated in vitro covalent binding

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Cytochrome P-4502E1-dependent formation of trifluoroacetyl adducts from halothane by transduced HepG2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Hapten carrier conjugates associated with halothane hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

UDP-glucose:glycoprotein glucosyltransferase associates with endoplasmic reticulum chaperones and its activity is decreased in vivo by the inhalation anesthetic halothane.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Detection of autoantibodies directed against human hepatic endoplasmic reticulum in sera from patients with halothane-associated hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Target proteins in human autoimmunity: cytochromes P450 and UDP- glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The pharmacology and clinical uses of tamoxifen

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Update on clinical role of tamoxifen

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The metabolic activation of tamoxifen and alpha-hydroxytamoxifen to DNA- binding species in rat hepatocytes proceeds via sulphation

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Bioactivation of tamoxifen by recombinant human cytochrome p450 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA.

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https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Effect of tamoxifen on the enzymatic activity of human cytochrome CYP2B6.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

4-Hydroxytamoxifen sulfation metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immune mechanisms in tienilic acid associated hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Measurement of acetaminophen-protein adducts in children and adolescents with acetaminophen overdoses. .

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

1 reference

7 January 2021

Practical aspects of the ligand-binding and enzymatic properties of human serum albumin.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Applicability of a modified Edman procedure for measurement of protein adducts: mechanisms of formation and degradation of phenylthiohydantoins

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanisms of the formation and disposition of reactive metabolites that can cause acute liver injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The danger hypothesis--potential role in idiosyncratic drug reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Immunopharmacology of hypersensitivity reactions to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Mechanism-based inactivation of cytochrome P450s 1A2 and 3A4 by dihydralazine in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Systemic lupus erythematosus induced by isoniazid

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

1 reference

7 January 2021

Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Neutrophil functions of patients with vasculitis related to myeloperoxidase-specific anti-neutrophil antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Thyroid autoantibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Outcome of acetaminophen overdose in pediatric patients and factors contributing to hepatotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Brief history of chemical carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Carcinogenesis: basic principles

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The role of covalent binding to microsomal proteins in the hepatotoxicity of acetaminophen.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Prediction of potential toxicity and side effect protein targets of a small molecule by a ligand-protein inverse docking approach

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

A review of the common properties of drugs with idiosyncratic hepatotoxicity and the "multiple determinant hypothesis" for the manifestation of idiosyncratic drug toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Prediction of toxicity from chemical structure

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Computer prediction of possible toxic action from chemical structure: an update on the DEREK system.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The computational prediction of toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Volatile N-nitrosamine formation after intake of nitrate at the ADI level in combination with an amine-rich diet

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Inhibition of carbamyl phosphate synthetase-I and glutamine synthetase by hepatotoxic doses of acetaminophen in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Identification of 10-formyltetrahydrofolate dehydrogenase-hydrolase as a major folate binding protein in liver cytosol.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Role of CYP2E1 in the hepatotoxicity of acetaminophen

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

The effect of carbamazepine and its reactive metabolite, 9-acridine carboxaldehyde, on immune cell function in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Kupffer cells from halothane-exposed guinea pigs carry trifluoroacetylated protein adducts.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Molecular structure and hepatotoxicity: compared data about two closely related thiophene compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Oxidation of Tienilic Acid by Human Yeast-Expressed Cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this Drug is A Mechanism-Based Inhibitor Specific for Cytochrome P-450 2C9

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450IA2. A specific marker of dihydralazine-induced hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2803%2900399-4

7 January 2021

10.1016/S1570-0232(03)00399-4

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14630144