(Q35603393)

9 August 2017

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title

Antisense oligonucleotide-based therapeutics for cancer (English)

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9 August 2017

Nicholas M Dean

1

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9 August 2017

C Frank Bennett

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

1 December 2003

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9 August 2017

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9 August 2017

22

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9 August 2017

9087-9096

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9 August 2017

56

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207231

9 August 2017

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cites work

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Hammerhead nailed down

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

In vivo suppression of Bcl-XL expression facilitates chemotherapy-induced leukaemia cell death in a SCID/NOD-Hu model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

A cytosine analog that confers enhanced potency to antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Inhibition of coagulation by a phosphorothioate oligonucleotide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Antisense oligonucleotides: promise and reality.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Gene silencing in mammals by small interfering RNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Phosphorothioate oligonucleotides inhibit the intrinsic tenase complex by an allosteric mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Antisense therapy in oncology: new hope for an old idea?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Inhibition of Bcl-xL expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Targeting RNA for degradation with a (2'-5')oligoadenylate-antisense chimera

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Identification of an estrogen-inducible phosphatase (PP5) that converts MCF-7 human breast carcinoma cells into an estrogen-independent phenotype when expressed constitutively

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Angiozyme: a novel angiogenesis inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Properties of cloned and expressed human RNase H1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Identification and partial purification of human double strand RNase activity. A novel terminating mechanism for oligoribonucleotide antisense drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Ancient pathways programmed by small RNAs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Caspase 8 small interfering RNA prevents acute liver failure in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Antisense oligonucleotide inhibition of Bcl-xL and Bid expression in liver regulates responses in a mouse model of Fas-induced fulminant hepatitis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207231

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207231

1 reference

Dimensions Publication ID

9 August 2017

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1 reference