(Q35626332)

20 December 2017

review article

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title

Efflux-mediated drug resistance in bacteria (English)

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20 December 2017

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Xian-Zhi Li

1

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20 December 2017

Hiroshi Nikaido

series ordinal

2

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20 December 2017

publication date

1 January 2004

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20 December 2017

published in

Drugs

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20 December 2017

volume

64

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20 December 2017

page(s)

159-204

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20 December 2017

issue

2

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20 December 2017

Disorders of gastrointestinal motility associated with diabetes mellitus

cites work

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Gastric electrical stimulation with short pulses reduces vomiting but not dysrhythmias in dogs.

21 January 2018

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Intracerebroventricular injection of streptozotocin causes neurotoxicity to myelin that contributes to spatial memory deficits in rats

21 January 2018

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Hyperglycemia induces abnormalities of gastric myoelectrical activity in patients with type I diabetes mellitus.

21 January 2018

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Gastric neuropeptides and gastric motor abnormality in streptozotocin-induced diabetic rats: observation for four weeks after streptozotocin

21 January 2018

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Antiseptic susceptibility and distribution of antiseptic-resistance genes in methicillin-resistant Staphylococcus aureus.

21 January 2018

1 reference

12 December 2020

The multidrug efflux transporter of Bacillus subtilis is a structural and functional homolog of the Staphylococcus NorA protein

1 reference

12 December 2020

Neisseria gonorrhoeae cell envelope: permeability to hydrophobic molecules.

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12 December 2020

Emr, an Escherichia coli locus for multidrug resistance

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12 December 2020

Beta-lactamase inhibitors are substrates for the multidrug efflux pumps of Pseudomonas aeruginosa

1 reference

12 December 2020

Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa.

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12 December 2020

The role of efflux in macrolide resistance

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12 December 2020

Multidrug resistance in enteric and other gram-negative bacteria

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12 December 2020

A two-component multidrug efflux pump, EbrAB, in Bacillus subtilis

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12 December 2020

The ostensible paradox of multidrug recognition.

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12 December 2020

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

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12 December 2020

Altered crystal violet permeability and lytic behavior in antibiotic-resistant and -sensitive mutants of Neisseria gonorrhoeae

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12 December 2020

SMR-type multidrug resistance pumps.

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12 December 2020

Characterization of a Pseudomonas aeruginosa efflux pump contributing to aminoglycoside impermeability

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12 December 2020

New antimicrobials in the management of cystic fibrosis

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12 December 2020

Analysis of a complete library of putative drug transporter genes in Escherichia coli

1 reference

12 December 2020

The major facilitator superfamily

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12 December 2020

Multidrug resistance in Klebsiella pneumoniae: a novel gene, ramA, confers a multidrug resistance phenotype in Escherichia coli.

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12 December 2020

Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli

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12 December 2020

Active efflux mechanisms for antimicrobial resistance

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12 December 2020

Functions of tetracycline efflux proteins that do not involve tetracycline

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12 December 2020

Complete nucleotide sequence of a 43-kilobase genomic island associated with the multidrug resistance region of Salmonella enterica serovar Typhimurium DT104 and its identification in phage type DT120 and serovar Agona

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12 December 2020

The Envelope of Mycobacteria

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12 December 2020

Efflux pumps and drug resistance in gram-negative bacteria.

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12 December 2020

A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

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12 December 2020

Accumulation of rifampicin by Mycobacterium aurum, Mycobacterium smegmatis and Mycobacterium tuberculosis

1 reference

12 December 2020

Cloning and characterization of the Burkholderia vietnamiensis norM gene encoding a multi-drug efflux protein

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12 December 2020

A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter

1 reference

12 December 2020

Precious things come in little packages.

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12 December 2020

Peptidomimetics of efflux pump inhibitors potentiate the activity of levofloxacin in Pseudomonas aeruginosa

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12 December 2020

The role of outer membrane and efflux pumps in the resistance of gram-negative bacteria. Can we improve drug access?

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12 December 2020

CmeABC functions as a multidrug efflux system in Campylobacter jejuni

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12 December 2020

Antibiotic resistance: an ecological imbalance

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12 December 2020

The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals

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12 December 2020

Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system

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12 December 2020

Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein

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12 December 2020

Outer membranes of gram-negative bacteria are permeable to steroid probes.

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12 December 2020

Crystal structure of the transcription activator BmrR bound to DNA and a drug

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12 December 2020

Isolation of cmr, a novel Escherichia coli chloramphenicol resistance gene encoding a putative efflux pump

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12 December 2020

Amino acid residues essential for function of the MexF efflux pump protein of Pseudomonas aeruginosa

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12 December 2020

Escherichia coli genes involved in resistance to pyrazinoic acid, the active component of the tuberculosis drug pyrazinamide

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12 December 2020

SmeC, an outer membrane multidrug efflux protein of Stenotrophomonas maltophilia

1 reference

12 December 2020

Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role of acrR mutations

1 reference

12 December 2020

Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications

1 reference

12 December 2020

Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454

1 reference

12 December 2020

Efflux pumps involved in toluene tolerance in Pseudomonas putida DOT-T1E.

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12 December 2020

Antibody analysis of the localisation, expression and stability of HlyD, the MFP component of the E. coli haemolysin translocator

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12 December 2020

The effect of reserpine, an inhibitor of multi-drug efflux pumps, on the in-vitro susceptibilities of fluoroquinolone-resistant strains of Streptococcus pneumoniae to norfloxacin

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12 December 2020

Inactivation of antibiotics and the dissemination of resistance genes

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12 December 2020

Outer membrane protein D2 catalyzes facilitated diffusion of carbapenems and penems through the outer membrane of Pseudomonas aeruginosa

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12 December 2020

Structural mechanisms of QacR induction and multidrug recognition

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12 December 2020

Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins

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12 December 2020

Non-PmrA-mediated multidrug resistance in Streptococcus pneumoniae.

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12 December 2020

Resistance to antibiotics and biocides among non-fermenting Gram-negative bacteria

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12 December 2020

Influence of the TonB energy-coupling protein on efflux-mediated multidrug resistance in Pseudomonas aeruginosa

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12 December 2020

EmrE, an Escherichia coli 12-kDa multidrug transporter, exchanges toxic cations and H+ and is soluble in organic solvents

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12 December 2020

Multidrug transporters and antibiotic resistance in Lactococcus lactis

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12 December 2020

Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa

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12 December 2020

Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

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12 December 2020

Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus.

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12 December 2020

Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium

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12 December 2020

Insertion mutagenesis and membrane topology model of the Pseudomonas aeruginosa outer membrane protein OprM.

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12 December 2020

Accumulation of tetracyclines by Escherichia coli K-12

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12 December 2020

Chunnel vision. Export and efflux through bacterial channel-tunnels

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12 December 2020

Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors

1 reference

12 December 2020

Overexpression of marA, soxS, or acrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli.

1 reference

12 December 2020

ABC transporters: physiology, structure and mechanism--an overview

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12 December 2020

[Alteration of permeability of bacterial envelope barrier in rifamdin-resistant Mycobacterium tuberculosis].

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12 December 2020

Role of outer membrane barrier in efflux-mediated tetracycline resistance of Escherichia coli

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12 December 2020

Nucleotide sequence analysis of a gene from Burkholderia (Pseudomonas) cepacia encoding an outer membrane lipoprotein involved in multiple antibiotic resistance.

1 reference

12 December 2020

Contributions of the AmpC beta-lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to beta-lactams

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12 December 2020

Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa

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12 December 2020

Novel ciprofloxacin-resistant, nalidixic acid-susceptible mutant of Staphylococcus aureus

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12 December 2020

Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli

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12 December 2020

Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa

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12 December 2020

Involvement of outer membrane protein TolC, a possible member of the mar-sox regulon, in maintenance and improvement of organic solvent tolerance of Escherichia coli K-12

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12 December 2020

Agents that increase the permeability of the outer membrane.

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12 December 2020

A novel compound, 1,1-dimethyl-5(1-hydroxypropyl)-4,6,7-trimethylindan, is an effective inhibitor of the tet(K) gene-encoded metal-tetracycline/H+ antiporter of Staphylococcus aureus

1 reference

12 December 2020

Extrusion of penem antibiotics by multicomponent efflux systems MexAB-OprM, MexCD-OprJ, and MexXY-OprM of Pseudomonas aeruginosa

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12 December 2020

Transient carbapenem resistance induced by salicylate in Pseudomonas aeruginosa associated with suppression of outer membrane protein D2 synthesis

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12 December 2020

An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli

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12 December 2020

Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update

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12 December 2020

The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC

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12 December 2020

Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity

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12 December 2020

The mexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: characterization of mutations compromising activity

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12 December 2020

Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

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12 December 2020

Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa

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12 December 2020

Positive selection for loss of tetracycline resistance.

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12 December 2020

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

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12 December 2020

Enterococci and vancomycin resistance

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12 December 2020

Role of active efflux in association with target gene mutations in fluoroquinolone resistance in clinical isolates of Vibrio cholerae

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12 December 2020

Regulation of ompF porin expression by salicylate in Escherichia coli

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12 December 2020

Silver-resistant mutants of Escherichia coli display active efflux of Ag+ and are deficient in porins

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12 December 2020

Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa

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12 December 2020

Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

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12 December 2020

The outer membrane component of the multidrug efflux pump from Pseudomonas aeruginosa may be a gated channel

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12 December 2020

Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in an experimental model of Pseudomonas aeruginosa acute pneumonia in rats

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12 December 2020

Involvement of an efflux system in high-level fluoroquinolone resistance of Shigella dysenteriae.

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12 December 2020

Amplifiable resistance to tetracycline, chloramphenicol, and other antibiotics in Escherichia coli: involvement of a non-plasmid-determined efflux of tetracycline

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12 December 2020

Molecular requirements for the inhibition of the tetracycline antiport protein and the effect of potent inhibitors on the growth of tetracycline-resistant bacteria.

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12 December 2020

Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1E

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12 December 2020

Construction of a series of mutants lacking all of the four major mex operons for multidrug efflux pumps or possessing each one of the operons from Pseudomonas aeruginosa PAO1: MexCD-OprJ is an inducible pump

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12 December 2020

Lipid-layer crystallization and preliminary three-dimensional structural analysis of AcrA, the periplasmic component of a bacterial multidrug efflux pump.

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12 December 2020

Lipoproteins in bacteria

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12 December 2020

Antibiotic resistance: era of the multidrug pump.

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12 December 2020

Novel macrolide-specific ABC-type efflux transporter in Escherichia coli

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12 December 2020

Isolation of chlorhexidine-resistant Pseudomonas aeruginosa from clinical lesions.

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12 December 2020

Development of multiple-antibiotic-resistant (Mar) mutants of Pseudomonas aeruginosa after serial exposure to fluoroquinolones

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12 December 2020

Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes.

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12 December 2020

Molecular surveillance of macrolide, tetracycline and quinolone resistance mechanisms in 1191 clinical European Streptococcus pneumoniae isolates

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12 December 2020

Multiresistant Staphylococcus aureus: genetics and evolution of epidemic Australian strains

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12 December 2020

Mutational analysis of the OprM outer membrane component of the MexA-MexB-OprM multidrug efflux system of Pseudomonas aeruginosa

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12 December 2020

Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication

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12 December 2020

Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220

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12 December 2020

A mutation in the 5' untranslated region increases stability of norA mRNA, encoding a multidrug resistance transporter of Staphylococcus aureus

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12 December 2020

High-level fluoroquinolone-resistant clinical isolates of Escherichia coli overproduce multidrug efflux protein AcrA.

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12 December 2020

An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin

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12 December 2020

Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria

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12 December 2020

Influence of mutations in the mexR repressor gene on expression of the MexA-MexB-oprM multidrug efflux system of Pseudomonas aeruginosa

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12 December 2020

Accumulation of 10 fluoroquinolones by wild-type or efflux mutant Streptococcus pneumoniae.

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12 December 2020

Permeability barrier to rifampin in mycobacteria

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12 December 2020

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.

1 reference

12 December 2020

The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system.

1 reference

12 December 2020

Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae: contributions of type II topoisomerase mutations and efflux to levels of resistance

1 reference

12 December 2020

Evidence that phosphate specific transporter is amplified in a fluoroquinolone resistant Mycobacterium smegmatis.

1 reference

12 December 2020

Crystal structure of bacterial multidrug efflux transporter AcrB

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12 December 2020

Gene in the major cotransduction gap of the Escherichia coli K-12 linkage map required for the expression of chromosomal resistance to tetracycline and other antibiotics

1 reference

12 December 2020

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

1 reference

12 December 2020

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin

1 reference

12 December 2020

Evolution and spread of antibiotic resistance

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12 December 2020

Molecular biology of the LysR family of transcriptional regulators

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12 December 2020

Pseudomonas aeruginosa reveals high intrinsic resistance to penem antibiotics: penem resistance mechanisms and their interplay

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12 December 2020

Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus

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12 December 2020

The AcrAB-TolC efflux pump contributes to multidrug resistance in the nosocomial pathogen Enterobacter aerogenes

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12 December 2020

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

1 reference

12 December 2020

Differential regulation of the mcb and emr operons of Escherichia coli: role of mcb in multidrug resistance.

1 reference

12 December 2020

EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli

1 reference

12 December 2020

Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide

1 reference

12 December 2020

The XylS/AraC family of regulators.

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12 December 2020

Mycobacterial cell wall: structure and role in natural resistance to antibiotics

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12 December 2020

Benzethonium chloride resistance in Pseudomonas aeruginosa isolated from clinical lesions.

1 reference

12 December 2020

Membrane topology of a multidrug efflux transporter, AcrB, in Escherichia coli

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12 December 2020

Mechanisms of action and resistance of older and newer fluoroquinolones

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12 December 2020

The multidrug efflux protein NorM is a prototype of a new family of transporters

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12 December 2020

mmr, a Mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors.

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12 December 2020

EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB.

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12 December 2020

Active efflux of organic solvents by Pseudomonas putida S12 is induced by solvents.

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12 December 2020

Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa.

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12 December 2020

Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes

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12 December 2020

Mycobacterium tuberculosis efpA encodes an efflux protein of the QacA transporter family

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12 December 2020

The methyl viologen-resistance-encoding gene smvA of Salmonella typhimurium.

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12 December 2020

Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA.

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12 December 2020

Function of the membrane fusion protein, MexA, of the MexA, B-OprM efflux pump in Pseudomonas aeruginosa without an anchoring membrane.

1 reference

12 December 2020

A novel assembly process of the multicomponent xenobiotic efflux pump in Pseudomonas aeruginosa

1 reference

12 December 2020

Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia

1 reference

12 December 2020

Mutational analysis of CvaA in the highly conserved domain of the membrane fusion protein family

1 reference

12 December 2020

Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

1 reference

12 December 2020

Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae.

1 reference

12 December 2020

Emergence of Enterococcus as a Significant Pathogen

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12 December 2020

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

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12 December 2020

Another look at antibiotic resistance. 1991 Fred Griffith Review Lecture

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12 December 2020

Efflux in bacteria: what do we really know about it?

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12 December 2020

Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene product.

1 reference

12 December 2020

Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters

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12 December 2020

Role of the multidrug efflux systems of Pseudomonas aeruginosa in organic solvent tolerance.

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12 December 2020

Subunit swapping in the Mex-extrusion pumps in Pseudomonas aeruginosa

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12 December 2020

Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa

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12 December 2020

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

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12 December 2020

A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin

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12 December 2020

Involvement of a natural transport system in the process of efflux-mediated drug resistance in Mycobacterium smegmatis

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12 December 2020

Cloning and characterization of a novel macrolide efflux gene, mreA, from Streptococcus agalactiae

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12 December 2020

When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams

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12 December 2020

Additive effect of tolC and rfa mutations on the hydrophobic barrier of the outer membrane of Escherichia coli K-12.

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12 December 2020

Efflux of the natural polyamine spermidine facilitated by the Bacillus subtilis multidrug transporter Blt

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12 December 2020

Chimeric analysis of the multicomponent multidrug efflux transporters from gram-negative bacteria.

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12 December 2020

Two types of Bacillus subtilis tetA(L) deletion strains reveal the physiological importance of TetA(L) in K(+) acquisition as well as in Na(+), alkali, and tetracycline resistance

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12 December 2020

Active efflux, a common mechanism for biocide and antibiotic resistance

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12 December 2020

The Lactococcal lmrP gene encodes a proton motive force-dependent drug transporter

1 reference

12 December 2020

Resistance of Pseudomonas aeruginosa PAO to nalidixic acid and low levels of beta-lactam antibiotics: mapping of chromosomal genes

1 reference

12 December 2020

Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa

1 reference

12 December 2020

Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae

1 reference

12 December 2020

Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae.

1 reference

12 December 2020

Importance of lipooligosaccharide structure in determining gonococcal resistance to hydrophobic antimicrobial agents resulting from the mtr efflux system.

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12 December 2020

The outer membrane as the penetration barrier against mupirocin in gram-negative enteric bacteria

1 reference

12 December 2020

Inheritance of low-level resistance to penicillin, tetracycline, and chloramphenicol in Neisseria gonorrhoeae

1 reference

12 December 2020

QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA.

1 reference

12 December 2020

Inducible NorA-mediated multidrug resistance in Staphylococcus aureus

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12 December 2020

Antimicrobial susceptibility patterns of enterococci in intensive care units in Sweden evaluated by different MIC breakpoint systems.

1 reference

12 December 2020

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

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12 December 2020

Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa

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12 December 2020

Organic solvent-tolerant mutants of Pseudomonas aeruginosa display multiple antibiotic resistance

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12 December 2020

Molecular pharmacological characterization of two multidrug transporters in Lactococcus lactis.

1 reference

12 December 2020

Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae

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12 December 2020

Involvement of waaY, waaQ, and waaP in the modification of Escherichia coli lipopolysaccharide and their role in the formation of a stable outer membrane.

1 reference

12 December 2020

The Escherichia coli ATP-binding cassette (ABC) proteins.

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12 December 2020

Expanding multiple antibiotic resistance among clinical strains of Vibrio cholerae isolated from 1992-7 in Calcutta, India

1 reference

12 December 2020

Contribution of the MexAB-OprM multidrug efflux system to the beta-lactam resistance of penicillin-binding protein and beta-lactamase-derepressed mutants of Pseudomonas aeruginosa.

1 reference

12 December 2020

Conformational changes of the Tet repressor induced by tetracycline trapping

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12 December 2020

Plasmid-determined tetracycline resistance involves new transport systems for tetracycline

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12 December 2020

Crystal structure of MtaN, a global multidrug transporter gene activator

1 reference

12 December 2020

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA.

1 reference

12 December 2020

Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria

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12 December 2020

Transcriptional organization of the czc heavy-metal homeostasis determinant from Alcaligenes eutrophus

1 reference

12 December 2020

Active efflux of antimicrobial agents in wild-type strains of enterococci.

1 reference

12 December 2020

The effect of reserpine, a modulator of multidrug efflux pumps, on the in vitro activity of tetracycline against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) possessing the tet(K) determinant.

1 reference

12 December 2020

Two-component signal transduction

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12 December 2020

Identification of a chromosomally encoded ABC-transport system with which the staphylococcal erythromycin exporter MsrA may interact

1 reference

12 December 2020

Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides

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12 December 2020

A family of bacterial regulators homologous to Gal and Lac repressors.

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12 December 2020

MRSA and MRSE: is there an answer?

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12 December 2020

Global and cognate regulators control the expression of the organic solvent efflux pumps TtgABC and TtgDEF of Pseudomonas putida

1 reference

12 December 2020

Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication

1 reference

12 December 2020

Toxic waste disposal in Escherichia coli

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12 December 2020

Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family

1 reference

12 December 2020

Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus

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12 December 2020

Enterococcus faecalis multi-drug resistance transporters: application for antibiotic discovery

1 reference

12 December 2020

Clinical isolate of a porinless Salmonella typhi resistant to high levels of chloramphenicol

1 reference

12 December 2020

Inhibition of the multidrug resistance efflux pump

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12 December 2020

Efflux pump-mediated quinolone resistance in Staphylococcus aureus strains wild type for gyrA, gyrB, grlA, and norA.

1 reference

12 December 2020

Do biocides select for antibiotic resistance?

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12 December 2020

Isolation and characterization of toluene-sensitive mutants from the toluene-resistant bacterium Pseudomonas putida GM73.

1 reference

12 December 2020

Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa

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12 December 2020

Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli

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12 December 2020

Recent progress in novel macrolides, quinolones, and 2-pyridones to overcome bacterial resistance

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12 December 2020

Two genes encoding a putative multidrug efflux pump of the RND/MFP family are cotranscribed with an rpoH gene in Bradyrhizobium japonicum.

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12 December 2020

NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus and its homolog in Escherichia coli

1 reference

12 December 2020

Antibacterial activity of 4,5-dihydroxy-2-cyclopentan-1-one (DHCP) and cloning of a gene conferring DHCP resistance in Escherichia coli.

1 reference

12 December 2020

Characterization of the MexC-MexD-OprJ multidrug efflux system in DeltamexA-mexB-oprM mutants of Pseudomonas aeruginosa

1 reference

12 December 2020

The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen

1 reference

12 December 2020

Expression of efflux pump gene pmrA in fluoroquinolone-resistant and -susceptible clinical isolates of Streptococcus pneumoniae

1 reference

12 December 2020

Contribution of outer membrane efflux protein OprM to antibiotic resistance in Pseudomonas aeruginosa independent of MexAB.

1 reference

12 December 2020

Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa

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12 December 2020

Screening of an inhibitor of the tetracycline efflux pump in a tetracycline-resistant clinical-isolate of Staphylococcus aureus 743.

1 reference

12 December 2020

Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.

1 reference

12 December 2020

Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps

1 reference

12 December 2020

Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli

1 reference

12 December 2020

A resistance-nodulation-cell division family xenobiotic efflux pump in an obligate anaerobe, Porphyromonas gingivalis

1 reference

12 December 2020

The relationships and susceptibilities of some industrial, laboratory and clinical isolates of Pseudomonas aeruginosa to some antibiotics and biocides

1 reference

12 December 2020

Expression of Pseudomonas aeruginosa multidrug efflux pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrug-sensitive Escherichia coli strain.

1 reference

12 December 2020

Expression of Escherichia coli TehA gives resistance to antiseptics and disinfectants similar to that conferred by multidrug resistance efflux pumps

1 reference

12 December 2020

Detection of multidrug-resistant Salmonella enterica serotype typhimurium DT104 based on a gene which confers cross-resistance to florfenicol and chloramphenicol.

1 reference

12 December 2020

nalB-type mutations causing the overexpression of the MexAB-OprM efflux pump are located in the mexR gene of the Pseudomonas aeruginosa chromosome

1 reference

12 December 2020

Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein

1 reference

12 December 2020

The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs.

1 reference

12 December 2020

AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants

1 reference

12 December 2020

Energetics and mechanism of drug transport mediated by the lactococcal multidrug transporter LmrP.

1 reference

12 December 2020

Permeability of the cell wall of Mycobacterium smegmatis.

1 reference

12 December 2020

Characterization of chloramphenicol and florfenicol resistance in Escherichia coli associated with bovine diarrhea

1 reference

12 December 2020

Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein.

1 reference

12 December 2020

Physical and biochemical characterization of the qacA gene encoding antiseptic and disinfectant resistance in Staphylococcus aureus.

1 reference

12 December 2020

Cloning of multidrug resistance gene pqrA from Proteus vulgaris

1 reference

12 December 2020

Increase in MICs of ciprofloxacin in vivo in two closely related clinical isolates of Enterobacter cloacae

1 reference

12 December 2020

Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals.

1 reference

12 December 2020

Salicylate-inducible antibiotic resistance in Pseudomonas cepacia associated with absence of a pore-forming outer membrane protein

1 reference

12 December 2020

Inducible, but not constitutive, resistance of gonococci to hydrophobic agents due to the MtrC-MtrD-MtrE efflux pump requires TonB-ExbB-ExbD proteins

1 reference

12 December 2020

Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis

1 reference

12 December 2020

Multidrug efflux pumps of gram-negative bacteria

1 reference

12 December 2020

Overexpression of the robA gene increases organic solvent tolerance and multiple antibiotic and heavy metal ion resistance in Escherichia coli.

1 reference

12 December 2020

Active efflux of fluoroquinolones in Mycobacterium smegmatis mediated by LfrA, a multidrug efflux pump

1 reference

12 December 2020

Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?

1 reference

12 December 2020

Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase

1 reference

12 December 2020

1 reference

12 December 2020

Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria

1 reference

12 December 2020

Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor

1 reference

12 December 2020

NorA functions as a multidrug efflux protein in both cytoplasmic membrane vesicles and reconstituted proteoliposomes

1 reference

12 December 2020

Interplay between chromosomal beta-lactamase and the MexAB-OprM efflux system in intrinsic resistance to beta-lactams in Pseudomonas aeruginosa

1 reference

12 December 2020

Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium.

1 reference

12 December 2020

The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump

1 reference

12 December 2020

EnvC, a new lipoprotein of the cytoplasmic membrane of Escherichia coli.

1 reference

12 December 2020

AcrA is a highly asymmetric protein capable of spanning the periplasm

1 reference

12 December 2020

AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity

1 reference

12 December 2020

Plasmid-mediated tetracycline resistance in Escherichia coli involves increased efflux of the antibiotic

1 reference

12 December 2020

Fluoroquinolone resistance among Gram-positive cocci

1 reference

12 December 2020

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

1 reference

12 December 2020

Involvement of the TonB system in tolerance to solvents and drugs in Pseudomonas putida DOT-T1E.

1 reference

12 December 2020

Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA

1 reference

12 December 2020

Redox signal transduction via iron-sulfur clusters in the SoxR transcription activator.

1 reference

12 December 2020

A set of genes encoding a second toluene efflux system in Pseudomonas putida DOT-T1E is linked to the tod genes for toluene metabolism

1 reference

12 December 2020

The transmembrane domains of the ABC multidrug transporter LmrA form a cytoplasmic exposed, aqueous chamber within the membrane

1 reference

12 December 2020

AcrD of Escherichia coli is an aminoglycoside efflux pump

1 reference

12 December 2020

Use of steroids to monitor alterations in the outer membrane of Pseudomonas aeruginosa

1 reference

12 December 2020

Porin channels in Escherichia coli: studies with beta-lactams in intact cells

1 reference

12 December 2020

TonB protein and energy transduction between membranes

1 reference

12 December 2020

In search of natural substrates and inhibitors of MDR pumps.

1 reference

12 December 2020

Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome

1 reference

12 December 2020

Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance

1 reference

12 December 2020

Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis

1 reference

12 December 2020

The baeSR two-component regulatory system activates transcription of the yegMNOB (mdtABCD) transporter gene cluster in Escherichia coli and increases its resistance to novobiocin and deoxycholate

1 reference

12 December 2020

Localization of the outer membrane subunit OprM of resistance-nodulation-cell division family multicomponent efflux pump in Pseudomonas aeruginosa.

1 reference

12 December 2020

Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia

1 reference

12 December 2020

Multiple antibiotic resistance in Stenotrophomonas maltophilia

1 reference

12 December 2020

Functional replacement of OprJ by OprM in the MexCD-OprJ multidrug efflux system of Pseudomonas aeruginosa

1 reference

12 December 2020

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

1 reference

12 December 2020

ABC transporters: bacterial exporters

1 reference

12 December 2020

Gonococcal sensitivity to fecal lipids can be mediated by an Mtr-independent mechanism.

1 reference

12 December 2020

Expression of the multidrug resistance transporter NorA from Staphylococcus aureus is modified by a two-component regulatory system

1 reference

12 December 2020

In vivo selection of Klebsiella pneumoniae strains with enhanced quinolone resistance during fluoroquinolone treatment of urinary tract infections

1 reference

12 December 2020

Mechanism of ligand recognition by BmrR, the multidrug-responding transcriptional regulator: mutational analysis of the ligand-binding site

1 reference

12 December 2020

Regulation of the permeability of the gonococcal cell envelope by the mtr system

1 reference

12 December 2020

Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa.

1 reference

12 December 2020

Hypersusceptibility of the Pseudomonas aeruginosa nfxB mutant to beta-lactams due to reduced expression of the ampC beta-lactamase

1 reference

12 December 2020

Multidrug resistance mechanisms: drug efflux across two membranes

1 reference

12 December 2020

A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron

1 reference

12 December 2020

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export

1 reference

12 December 2020

Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon.

1 reference

12 December 2020

The Escherichia coli cmlA gene encodes the multidrug efflux pump Cmr/MdfA and is responsible for isopropyl-beta-D-thiogalactopyranoside exclusion and spectinomycin sensitivity

1 reference

12 December 2020

Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia

1 reference

12 December 2020

In vivo selection of a target/efflux double mutant of Pseudomonas aeruginosa by ciprofloxacin therapy

1 reference

12 December 2020

Different erythromycin resistance mechanisms in group C and group G streptococci

1 reference

12 December 2020

Evidence for the existence of a multidrug efflux transporter distinct from NorA in Staphylococcus aureus

1 reference

12 December 2020

ABC Transporters: From Microorganisms to Man

1 reference

12 December 2020

A common binding site for substrates and protons in EmrE, an ion-coupled multidrug transporter.

1 reference

12 December 2020

Two novel families of bacterial membrane proteins concerned with nodulation, cell division and transport

1 reference

12 December 2020

Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa

1 reference

12 December 2020

Interplay between the efflux pump and the outer membrane permeability barrier in fluorescent dye accumulation in Pseudomonas aeruginosa

1 reference

12 December 2020

Quorum sensing: the explanation of a curious phenomenon reveals a common characteristic of bacteria

1 reference

12 December 2020

Evidence for chloramphenicol/H+ antiport in Cmr (MdfA) system of Escherichia coli and properties of the antiporter.

1 reference

12 December 2020

Mechanisms of beta-lactam resistance in British isolates of Pseudomonas aeruginosa.

1 reference

12 December 2020

Beta-lactamase inhibitors: agents to overcome bacterial resistance

1 reference

12 December 2020

Introduction of a norA promoter region mutation into the chromosome of a fluoroquinolone-susceptible strain of Staphylococcus aureus using plasmid integration

1 reference

12 December 2020

Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those beta-lactam antibiotics containing lipophilic side chains.

1 reference

12 December 2020

Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa

1 reference

12 December 2020

Chloramphenicol resistance in Pseudomonas cepacia because of decreased permeability

1 reference

12 December 2020

nfxC-type quinolone resistance in a clinical isolate of Pseudomonas aeruginosa

1 reference

12 December 2020

Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes

1 reference

12 December 2020

Active efflux of ofloxacin by a highly quinolone-resistant strain of Proteus vulgaris

1 reference

12 December 2020

Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.

1 reference

12 December 2020

Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivo

1 reference

12 December 2020

How to distinguish between the vacuum cleaner and flippase mechanisms of the lmrA multi-drug transporter in Lactococcus lactis

1 reference

12 December 2020

Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa

1 reference

12 December 2020

Cloning and sequence analysis of an EnvCD homologue in Pseudomonas aeruginosa: regulation by iron and possible involvement in the secretion of the siderophore pyoverdine.

1 reference

12 December 2020

Cloning and organization of the abc and mdl genes of Escherichia coli: relationship to eukaryotic multidrug resistance

1 reference

12 December 2020

Activity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays

1 reference

12 December 2020

Inner membrane efflux components are responsible for beta-lactam specificity of multidrug efflux pumps in Pseudomonas aeruginosa

1 reference

12 December 2020

Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

1 reference

12 December 2020

Mystery of multidrug transporters: the answer can be simple

1 reference

12 December 2020

Na+-driven multidrug efflux pump VcmA from Vibrio cholerae non-O1, a non-halophilic bacterium

1 reference

12 December 2020

A multidrug efflux transporter in Listeria monocytogenes.

1 reference

12 December 2020

In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system MexA-MexB-OprM.

1 reference

12 December 2020

Fluoroquinolone susceptibilities of efflux-mediated multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Burkholderia cepacia

1 reference

12 December 2020

Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis

1 reference

12 December 2020

Salicylate reduces susceptibility of Mycobacterium tuberculosis to multiple antituberculosis drugs

1 reference

12 December 2020

The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae

1 reference

12 December 2020

Antibiotic resistance caused by gram-negative multidrug efflux pumps

1 reference

12 December 2020

Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms.

1 reference

12 December 2020

Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli

1 reference

12 December 2020

The periplasmic murein peptide-binding protein MppA is a negative regulator of multiple antibiotic resistance in Escherichia coli

1 reference

12 December 2020

Functional analysis of novel multidrug transporters from human pathogens

1 reference

12 December 2020

Multiple novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.

1 reference

12 December 2020

The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis

1 reference

12 December 2020

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

1 reference

12 December 2020

Characterization of In40 of Enterobacter aerogenes BM2688, a class 1 integron with two new gene cassettes, cmlA2 and qacF.

1 reference

12 December 2020

Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae.

1 reference

12 December 2020

Isolation and characterization of a putative multidrug resistance pump from Vibrio cholerae

1 reference

12 December 2020

Effects of salicylate and related compounds on fusidic acid MICs in Staphylococcus aureus.

1 reference

12 December 2020

Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa

1 reference

12 December 2020

Reversal of tetracycline resistance mediated by different bacterial tetracycline resistance determinants by an inhibitor of the Tet(B) antiport protein.

1 reference

12 December 2020

The lactococcal secondary multidrug transporter LmrP confers resistance to lincosamides, macrolides, streptogramins and tetracyclines.

1 reference

12 December 2020

Influence of the MexA-MexB-oprM multidrug efflux system on expression of the MexC-MexD-oprJ and MexE-MexF-oprN multidrug efflux systems in Pseudomonas aeruginosa.

1 reference

12 December 2020

The multidrug efflux pump NorA is not required for salicylate-induced reduction in drug accumulation by Staphylococcus aureus

1 reference

12 December 2020

The effect of sodium salicylate on antibiotic susceptibility and synergy in Klebsiella pneumoniae

1 reference

12 December 2020

Energetics and topology of CzcA, a cation/proton antiporter of the resistance-nodulation-cell division protein family

1 reference

12 December 2020

The MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosan

1 reference

12 December 2020

Thiolactomycin resistance in Escherichia coli is associated with the multidrug resistance efflux pump encoded by emrAB

1 reference

12 December 2020

Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa

1 reference

12 December 2020

Antimicrobial susceptibilities of 1,684 Streptococcus pneumoniae and 2,039 Streptococcus pyogenes isolates and their ecological relationships: results of a 1-year (1998-1999) multicenter surveillance study in Spain

1 reference

12 December 2020

Evaluation of a structural model of Pseudomonas aeruginosa outer membrane protein OprM, an efflux component involved in intrinsic antibiotic resistance

1 reference

12 December 2020

Biocide abuse and antimicrobial resistance--a cause for concern?

1 reference

12 December 2020

Characterization of emeA, a NorA homolog and multidrug resistance efflux pump, in Enterococcus faecalis

1 reference

12 December 2020

Outer membranes and efflux: the path to multidrug resistance in Gram-negative bacteria

1 reference

12 December 2020

Fluoroquinolone resistance of Serratia marcescens: involvement of a proton gradient-dependent efflux pump

1 reference

12 December 2020

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

1 reference

12 December 2020

Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes

1 reference

12 December 2020

Regulation of bacterial drug export systems

1 reference

12 December 2020

Topological analysis of an RND family transporter, MexD of Pseudomonas aeruginosa.

1 reference

12 December 2020

Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa.

1 reference

12 December 2020

Decreased permeability and enhanced proton-dependent active efflux in the development of resistance to quinolones in Morganella morganii.

1 reference

12 December 2020

marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli

1 reference

12 December 2020

MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region

1 reference

12 December 2020

Porin channels in Escherichia coli: studies with liposomes reconstituted from purified proteins

1 reference

12 December 2020

Intrinsic resistance to inhibitors of fatty acid biosynthesis in Pseudomonas aeruginosa is due to efflux: application of a novel technique for generation of unmarked chromosomal mutations for the study of efflux systems

1 reference

12 December 2020

Biochemical coupling between the DrrA and DrrB proteins of the doxorubicin efflux pump of Streptomyces peucetius

1 reference

12 December 2020

Characterization of a putative RND-type efflux system in Agrobacterium tumefaciens

1 reference

12 December 2020

Negative regulation of the Pseudomonas aeruginosa outer membrane porin OprD selective for imipenem and basic amino acids

1 reference

12 December 2020

An E. coli gene emrD is involved in adaptation to low energy shock.

1 reference

12 December 2020

Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei

1 reference

12 December 2020

Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

12 December 2020

Detection of tetracyclines and efflux pump inhibitors

1 reference

12 December 2020

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

1 reference

12 December 2020

Gram-positive resistance: challenge for the development of new antibiotics

1 reference

12 December 2020

Characterization of MarR, the repressor of the multiple antibiotic resistance (mar) operon in Escherichia coli

1 reference

12 December 2020

Sequence analysis of the florfenicol resistance gene encoded in the transferable R-plasmid of a fish pathogen, Pasteurella piscicida.

1 reference

12 December 2020

Gene-Controlled Resistance to Acriflavine and Other Basic Dyes in Escherichia coli

1 reference

12 December 2020

Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli

1 reference

12 December 2020

Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA,B-OprM extrusion pump in Pseudomonas aeruginosa.

1 reference

12 December 2020

Antibacterial activity of gatifloxacin (AM-1155, CG5501, BMS-206584), a newly developed fluoroquinolone, against sequentially acquired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus

1 reference

12 December 2020

Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway

1 reference

12 December 2020

Purification and characterization of the Pseudomonas aeruginosa NfxB protein, the negative regulator of the nfxB gene

1 reference

12 December 2020

Sensitivity of Escherichia coli to various beta-lactams is determined by the interplay of outer membrane permeability and degradation by periplasmic beta-lactamases: a quantitative predictive treatment

1 reference

12 December 2020

Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences

1 reference

12 December 2020

Overexpression of the Escherichia coli sugE gene confers resistance to a narrow range of quaternary ammonium compounds

1 reference

12 December 2020

Salmonella typhimurium acrB-like gene: identification and role in resistance to biliary salts and detergents and in murine infection.

1 reference

12 December 2020

An isoflavonoid-inducible efflux pump in Agrobacterium tumefaciens is involved in competitive colonization of roots

1 reference

12 December 2020

Proton-dependent multidrug efflux systems

1 reference

12 December 2020

Outer membrane barrier as a mechanism of antimicrobial resistance

1 reference

12 December 2020

Interplay between the MexA-MexB-OprM multidrug efflux system and the outer membrane barrier in the multiple antibiotic resistance of Pseudomonas aeruginosa

1 reference

12 December 2020

Mechanisms of fluoroquinolone resistance: an update 1994-1998.

1 reference

12 December 2020

A tetrameric porin limits the cell wall permeability of Mycobacterium smegmatis

1 reference

12 December 2020

A model for coupling of H(+) and substrate fluxes based on "time-sharing" of a common binding site

1 reference

12 December 2020

EmrE, the smallest ion-coupled transporter, provides a unique paradigm for structure-function studies

1 reference

12 December 2020

A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria

1 reference

12 December 2020

On the mechanism of substrate specificity by resistance nodulation division (RND)-type multidrug resistance pumps: the large periplasmic loops of MexD from Pseudomonas aeruginosa are involved in substrate recognition

1 reference

12 December 2020

Efflux-mediated resistance to fluoroquinolones in gram-positive bacteria and the mycobacteria

1 reference

12 December 2020

Apparent involvement of a multidrug transporter in the fluoroquinolone resistance of Streptococcus pneumoniae

1 reference

12 December 2020

MC-207110 Daiichi Seiyaku/Microcide Pharmaceuticals.

1 reference

12 December 2020

Susceptibility of antibiotic-resistant Gram-negative bacteria to biocides: a perspective from the study of catheter biofilms

1 reference

12 December 2020

Phenotypic and molecular characterization of conjugative antibiotic resistance plasmids isolated from bacterial communities of activated sludge.

1 reference

12 December 2020

Identification and molecular characterization of an efflux pump involved in Pseudomonas putida S12 solvent tolerance.

1 reference

12 December 2020

Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents.

1 reference

12 December 2020

Control of the AcrAB multidrug efflux pump by quorum-sensing regulator SdiA.

1 reference

12 December 2020

Growth in the presence of salicylate increases fluoroquinolone resistance in Staphylococcus aureus

1 reference

12 December 2020

Induction of the mtrCDE-encoded efflux pump system of Neisseria gonorrhoeae requires MtrA, an AraC-like protein

1 reference

12 December 2020

Induction of SOS genes in Escherichia coli and mutagenesis in Salmonella typhimurium by fluoroquinolones

1 reference

12 December 2020

Molecular cloning and characterization of acrA and acrE genes of Escherichia coli

1 reference

12 December 2020

Mechanisms and frequency of resistance to premafloxacin in Staphylococcus aureus: novel mutations suggest novel drug-target interactions

1 reference

12 December 2020

mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.

1 reference

12 December 2020

Multiple antibiotic resistance in Stenotrophomonas maltophilia: involvement of a multidrug efflux system

1 reference

12 December 2020

Identification of an immunodominant drug efflux pump in Burkholderia cepacia

1 reference

12 December 2020

Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals

1 reference

12 December 2020

Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression

1 reference

12 December 2020

Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli

1 reference

12 December 2020

Frequency and genetic characterization of multidrug-resistant mutants of Staphylococcus aureus after selection with individual antiseptics and fluoroquinolones.

1 reference

12 December 2020

Contribution of multidrug efflux pumps to multiple antibiotic resistance in veterinary clinical isolates of Pseudomonas aeruginosa.

1 reference

12 December 2020

The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids.

1 reference

12 December 2020

Isoniazid accumulation in Mycobacterium smegmatis is modulated by proton motive force-driven and ATP-dependent extrusion systems

1 reference

12 December 2020

Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms

1 reference

12 December 2020

SmeDEF multidrug efflux pump contributes to intrinsic multidrug resistance in Stenotrophomonas maltophilia

1 reference

12 December 2020

High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation

1 reference

12 December 2020

Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance

1 reference

12 December 2020

A staphylococcal multidrug resistance gene product is a member of a new protein family

1 reference

12 December 2020

Characterization of P55, a multidrug efflux pump in Mycobacterium bovis and Mycobacterium tuberculosis

1 reference

12 December 2020

Prevention of drug access to bacterial targets: permeability barriers and active efflux

1 reference

12 December 2020

Preventing drug access to targets: cell surface permeability barriers and active efflux in bacteria

1 reference

12 December 2020

Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops

1 reference

12 December 2020

The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution

1 reference

12 December 2020

Interactions of dedicated export membrane proteins of the colicin V secretion system: CvaA, a member of the membrane fusion protein family, interacts with CvaB and TolC.

1 reference

12 December 2020

A convenient assay for estimating the possible involvement of efflux of fluoroquinolones by Streptococcus pneumoniae and Staphylococcus aureus: evidence for diminished moxifloxacin, sparfloxacin, and trovafloxacin efflux.

1 reference

12 December 2020

Non-gyrA-mediated ciprofloxacin resistance in laboratory mutants of Streptococcus pneumoniae

1 reference

12 December 2020

Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis

1 reference

12 December 2020

Antibacterial efflux systems.

1 reference

12 December 2020

Evidence for an efflux pump in multidrug-resistant Campylobacter jejuni

1 reference

12 December 2020

Gonococcal strains from homosexual men have outer membranes with reduced permeability to hydrophobic molecules

1 reference

12 December 2020

Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance

1 reference

12 December 2020

Comparative distribution of resistance patterns and serotypes in Pseudomonas aeruginosa isolates from intensive care units and other wards

1 reference

12 December 2020

New developments in tetracycline antibiotics: glycylcyclines and tetracycline efflux pump inhibitors

1 reference

12 December 2020

Antimicrobial resistance of Staphylococcus aureus: genetic basis.

1 reference

12 December 2020

Isolation and transposon mutagenesis of a Pseudomonas putida KT2442 toluene-resistant variant: involvement of an efflux system in solvent resistance

1 reference

12 December 2020

Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae

1 reference

12 December 2020

Verapamil-tobramycin synergy in Pseudomonas cepacia but not Pseudomonas aeruginosa in vitro.

1 reference

12 December 2020

TolC of Escherichia coli functions as an outer membrane channel.

1 reference

12 December 2020

Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin

1 reference

12 December 2020

Major facilitator superfamily

1 reference

12 December 2020

Cross-resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps: exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ.

1 reference

12 December 2020

Association between intensity of chlorhexidine use and micro-organisms of reduced susceptibility in a hospital environment

1 reference

12 December 2020

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance

1 reference

12 December 2020

Identification of essential charged residues in transmembrane segments of the multidrug transporter MexB of Pseudomonas aeruginosa

1 reference

12 December 2020

A new subfamily of bacterial ABC-type transport systems catalyzing export of drugs and carbohydrates

1 reference

12 December 2020

A family of gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from gram-negative bacteria

1 reference

12 December 2020

Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters

1 reference

12 December 2020

The secondary multidrug transporter LmrP contains multiple drug interaction sites.

1 reference

12 December 2020

Genetic organization and regulation of antimicrobial efflux systems possessed by Neisseria gonorrhoeae and Neisseria meningitidis.

1 reference

12 December 2020

Identifiers

DOI

10.1159/000081516

1 reference

20 December 2017

PubMed ID

14717618

1 reference

20 December 2017