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The mediator complex
scientific article published on January 2004
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
The mediator complex
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
author name string
Stefan Björklund
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
Claes M Gustafsson
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
publication date
1 January 2004
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
published in
Advances in Protein Chemistry
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
volume
67
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
page(s)
43-65
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
cites work
What does 'chromatin remodeling' mean?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
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Conserved structures of mediator and RNA polymerase II holoenzyme
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7 January 2021
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inferred from DOI database lookup
The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression.
1 reference
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7 January 2021
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Functional interactions within yeast mediator and evidence of differential subunit modifications
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reference URL
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7 January 2021
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Three subunits of the RNA polymerase II mediator complex are involved in glucose repression.
1 reference
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7 January 2021
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Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein
1 reference
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Regulation of nuclear genes encoding mitochondrial proteins in Saccharomyces cerevisiae
1 reference
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7 January 2021
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A mammalian SRB protein associated with an RNA polymerase II holoenzyme
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Med8, a subunit of the mediator CTD complex of RNA polymerase II, directly binds to regulatory elements of SUC2 and HXK2 genes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF
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7 January 2021
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Structural organization of yeast and mammalian mediator complexes
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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A mediator required for activation of RNA polymerase II transcription in vitro
1 reference
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reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
1 reference
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Srb7p is essential for the activation of a subset of genes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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inferred from DOI database lookup
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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inferred from DOI database lookup
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Dissecting the regulatory circuitry of a eukaryotic genome
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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inferred from DOI database lookup
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.
1 reference
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7 January 2021
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An activator target in the RNA polymerase II holoenzyme
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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An RNA polymerase II holoenzyme responsive to activators
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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inferred from DOI database lookup
Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
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Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
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Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
An activator binding module of yeast RNA polymerase II holoenzyme
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
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Nuclear receptor cofactors as chromatin remodelers
1 reference
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A kinase-cyclin pair in the RNA polymerase II holoenzyme.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mediator-nucleosome interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of class II gene transcription by regulatory factors is potentiated by a novel activity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA polymerase II holoenzymes and subcomplexes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
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The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediator protein mutations that selectively abolish activated transcription
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediator of Transcriptional Regulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Composite co-activator ARC mediates chromatin-directed transcriptional activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo requirement of activator-specific binding targets of mediator
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association of an X-chromosome dodecamer insertional variant allele with mental retardation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex
1 reference
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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast TAF(II)145 functions as a core promoter selectivity factor, not a general coactivator
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast GAL11 protein is involved in regulation of the structure and the position effect of telomeres
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a mediator cycle at the initiation of transcription.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
General requirement for RNA polymerase II holoenzymes in vivo
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin remodeling and transcriptional activation: the cast (in order of appearance).
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of mediator complexes from HeLa cell nuclear extract
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SPT13 (GAL11) of Saccharomyces cerevisiae negatively regulates activity of the MCM1 transcription factor in Ty1 elements
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcription reinitiation intermediate that is stabilized by activator
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Schizosaccharomyces pombe sep15+ gene encodes a protein homologous to the Med8 subunit of the Saccharomyces cerevisiae transcriptional mediator complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-3233(04)67002-1
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
PubMed ID
14969723
1 reference
stated in
Europe PubMed Central
PubMed ID
14969723
retrieved
9 August 2017
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