(Q35681634)

9 August 2017

1 reference

title

Rho-regulatory proteins in breast cancer cell motility and invasion (English)

1 reference

9 August 2017

1 reference

Min Lin

1

1 reference

9 August 2017

Kenneth L van Golen

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

1 March 2004

1 reference

Breast Cancer Research and Treatment

9 August 2017

1 reference

9 August 2017

84

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9 August 2017

49-60

1 reference

9 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1023/b:brea.0000018424.43445.f3

9 August 2017

0 references

cites work

Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho.

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21 January 2018

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Characterization and expression of the human rhoH12 gene product

21 January 2018

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Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability

21 January 2018

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https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

21 January 2018

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https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones. Involvement of chromosomes 4 and 14

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Signaling to Rho GTPases

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho proteins induce metastatic properties in vivo

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Function of the Rho family GTPases in Ras-stimulated Raf activation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho family proteins: coordinating cell responses

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

A novel ras-related gene family

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Genomic structure and assignment of the RhoH/TTF small GTPase gene (ARHH) to 4p13 by in situ hybridization

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho proteins: targets for bacterial toxins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Botulinum ADP-ribosyltransferase C3: a new tool to study low molecular weight GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Microinjection of recombinant p21rho induces rapid changes in cell morphology

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The cellular functions of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Membrane ruffling and signal transduction

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho-like GTPases in tumor cell invasion

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho GTPase signalling pathways in the morphological changes associated with apoptosis.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho GTPases are over-expressed in human tumors.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Involvement of small GTPases Rho and Rac in the invasion of rat ascites hepatoma cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Genomic analysis of metastasis reveals an essential role for RhoC

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

rho gene amplification and malignant transformation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Mutation status of genes encoding RhoA, Rac1, and Cdc42 GTPases in a panel of invasive human colorectal and breast tumors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Inflammatory breast cancer: a review

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Breast cancer in women under 30 years of age.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

In vitro binding assay for interactions of Rho and Rac with GTPase-activating proteins and effectors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Guanine nucleotide exchange factors for the Rho GTPases: a role in human disease?

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Untying the Gordian knot of cytokinesis. Role of small G proteins and their regulators

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The specific binding of small molecule isoprenoids to rhoGDP dissociation inhibitor (rhoGDI)

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Guanine nucleotide exchange factors: activators of Ras superfamily proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

GTPase-activating proteins: helping hands to complement an active site.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

GTPase-activating proteins and their complexes.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

In vivo prenylation analysis of Ras and Rho proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Rho GTPases as modulators of the estrogen receptor transcriptional response

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

ER beta inhibits proliferation and invasion of breast cancer cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of Akt kinase activity by farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Autoinhibition mechanism of proto-Dbl.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Signaling to the Rho GTPases: networking with the DH domain

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Pleckstrin homology domains: a common fold with diverse functions.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Phosphorylation of the p190 RhoGAP N-terminal domain by c-Src results in a loss of GTP binding activity

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Vav family proteins couple to diverse cell surface receptors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Vav proteins, adaptors and cell signaling.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Role of p120 Ras-GAP in directed cell movement

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

E-cadherin engagement stimulates tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

Evidence for a novel RasGAP-associated protein of 105 kDa in both mature trophoblasts and differentiating choriocarcinoma cells.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018424.43445.F3

7 January 2021

10.1023/B:BREA.0000018424.43445.F3

Identifiers

DOI

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference