(Q35707246)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Henry Duff

22

1 reference

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7 February 2020

Long-Sheng Song

25

1 reference

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7 February 2020

17

Weizhong Zhu

1 reference

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7 February 2020

9

Wenqian Chen

1 reference

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7 February 2020

4

Ruiwu Wang

1 reference

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7 February 2020

13

Xiaowei Zhong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

8

Cuihong Xie

1 reference

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7 February 2020

10

Jingqun Zhang

1 reference

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7 February 2020

11

Xixi Tian

1 reference

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7 February 2020

28

S R Wayne Chen

1 reference

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7 February 2020

23

Heping Cheng

1 reference

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7 February 2020

author name string

Qiang Zhou

1

1 reference

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7 February 2020

Jianmin Xiao

2

1 reference

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7 February 2020

Dawei Jiang

3

1 reference

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7 February 2020

Kannan Vembaiyan

5

1 reference

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7 February 2020

Aixia Wang

6

1 reference

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7 February 2020

Chris D Smith

7

1 reference

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7 February 2020

Peter P Jones

12

1 reference

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7 February 2020

Haiyan Chen

15

1 reference

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7 February 2020

Lin Zhang

16

1 reference

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7 February 2020

Dongmei Yang

18

1 reference

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7 February 2020

Xiaodong Li

19

1 reference

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7 February 2020

Ju Chen

20

1 reference

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7 February 2020

Anne M Gillis

21

1 reference

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7 February 2020

Arthur M Feldman

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Michael Fill

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Thomas G Back

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

10 July 2011

1 reference

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7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

1003-1009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.2406

7 February 2020

exact match

0 references

cites work

Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

1 reference

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Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.

12 July 2018

1 reference

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Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

12 July 2018

1 reference

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Arrhythmogenic consequences of intracellular calcium waves

12 July 2018

1 reference

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Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardia

12 July 2018

1 reference

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Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

12 July 2018

1 reference

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The role of antiarrhythmic drug therapy for the prevention of sudden cardiac death

12 July 2018

1 reference

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Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia

12 July 2018

1 reference

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Atherosclerosis and oxidant stress: the end of the road for antioxidant vitamin treatment?

12 July 2018

1 reference

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K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association

12 July 2018

1 reference

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Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.

12 July 2018

1 reference

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Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.

12 July 2018

1 reference

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RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Carvedilol: beta-blockade and beyond.

12 July 2018

1 reference

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Nonselective versus selective beta-blockers in the management of chronic heart failure: clinical implications of the carvedilol or Metoprolol European Trial.

12 July 2018

1 reference

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Cellular basis of triggered arrhythmias in heart failure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure

12 July 2018

1 reference

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Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial

12 July 2018

1 reference

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Limitations of current medical therapies for the treatment of heart failure

12 July 2018

1 reference

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Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.

12 July 2018

1 reference

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beta-Blocker therapy in heart failure: scientific review

12 July 2018

1 reference

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Calcium and cardiac rhythms: physiological and pathophysiological

12 July 2018

1 reference

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Cardioprotection with beta-adrenoceptor blockers. Does lipophilicity matter?

12 July 2018

1 reference

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Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol.

12 July 2018

1 reference

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Carvedilol, a cardiovascular drug, prevents vascular smooth muscle cell proliferation, migration, and neointimal formation following vascular injury

12 July 2018

1 reference

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Oscillations of intracellular Ca2+ in mammalian cardiac muscle.

12 July 2018

1 reference

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Scattered-light intensity fluctuations in diastolic rat cardiac muscle caused by spontaneous Ca++-dependent cellular mechanical oscillations

12 July 2018

1 reference

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Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers

12 July 2018

1 reference

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Cellular calcium fluctuations in mammalian heart: direct evidence from noise analysis of aequorin signals in Purkinje fibers

12 July 2018

1 reference

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Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle

12 July 2018

1 reference

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Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial

12 July 2018

1 reference

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Stereoselective disposition and tissue distribution of carvedilol enantiomers in rats

12 July 2018

1 reference

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Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Which beta-blocker is most effective in heart failure?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Scavenging free radicals by low-dose carvedilol prevents redox-dependent Ca2+ leak via stabilization of ryanodine receptor in heart failure.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Antiarrhythmic effect of carvedilol after acute myocardial infarction: results of the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN) trial

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Adverse effects of beta-blocker therapy for patients with heart failure: a quantitative overview of randomized trials

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Characteristic effects of alpha1-beta1,2-adrenergic blocking agent, carvedilol, on [Ca2+]i in ventricular myocytes compared with those of timolol and atenolol

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268079

Sarcoplasmic Reticulum Ca2+ Release Causes Myocyte Depolarization : Underlying Mechanism and Threshold for Triggered Action Potentials

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2406

Pharmacokinetics and disposition of carvedilol in humans

21 January 2018

1 reference

12 December 2020

Carvedilol stereopharmacokinetics in rats: affinities to blood constituents and tissues

1 reference

12 December 2020

Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts

1 reference

12 December 2020

Combined alpha-beta blockade (doxazosin plus metoprolol) compared with beta blockade alone in chronic congestive heart failure

1 reference

12 December 2020

Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model

1 reference

12 December 2020

Steady-state pharmacokinetics of carvedilol and its enantiomers in patients with congestive heart failure

1 reference

12 December 2020

Mutant ryanodine receptors in catecholaminergic polymorphic ventricular tachycardia generate delayed afterdepolarizations due to increased propensity to Ca2+ waves

1 reference

12 December 2020

Structure-Lipophilicity Relationships of Neutral and Protonatedβ-Blockers, Part I, Intra- and Intermolecular Effects in Isotropic Solvent Systems

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2406

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21743453%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference