(Q35746645)

10 August 2017

title

Allelic analysis of serous ovarian carcinoma reveals two putative tumor suppressor loci at 18q22-q23 distal to SMAD4, SMAD2, and DCC. (English)

1 reference

10 August 2017

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3

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10 August 2017

H Lassus

1

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10 August 2017

R Salovaara

series ordinal

2

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10 August 2017

R Butzow

series ordinal

4

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10 August 2017

language of work or name

English

0 references

publication date

1 July 2001

1 reference

The American Journal of Pathology

10 August 2017

published in

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10 August 2017

volume

159

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10 August 2017

issue

1

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10 August 2017

page(s)

35-42

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Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Loss of DCC gene expression during ovarian tumorigenesis: relation to tumour differentiation and progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Identification of expressed genes by laser-mediated manipulation of single cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Tissue microarrays for high-throughput molecular profiling of tumor specimens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

The DCC protein and prognosis in colorectal cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Mutations of the E-cadherin gene in human gynecologic cancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Loss of expression and loss of heterozygosity in the DCC gene in neoplasms of the human female reproductive tract

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Identification of a chromosome 18q gene that is altered in colorectal cancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary

27 July 2018

1 reference

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Human epithelial ovarian cancer allelotype.

27 July 2018

1 reference

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p53 mutation is a common genetic event in ovarian carcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Frequent loss of heterozygosity on chromosome 18 in ovarian adenocarcinoma which does not always include the DCC locus

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850432

Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer

15 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Allelic imbalance in chromosome band 18q21 and SMAD4 mutations in ovarian cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Genetic alterations distinguish different types of ovarian tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Transforming growth factor beta signal transducer Smad2 is expressed in mouse meiotic germ cells, Sertoli cells, and Leydig cells during spermatogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Comparison of serous and mucinous ovarian carcinomas: distinct pattern of allelic loss at distal 8p and expression of transcription factor GATA-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Allelic loss of chromosome 18q and prognosis in colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Somatic genetic alterations (LOH) in benign, borderline and invasive ovarian tumours: intratumoral molecular heterogeneity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961670-7

Analysis of specific gene mutations in the transforming growth factor-beta signal transduction pathway in human ovarian cancer

7 January 2021

1 reference

12 December 2020

An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer

1 reference

12 December 2020

Allelotype of human ovarian cancer

1 reference

12 December 2020

DPC4 gene in various tumor types

1 reference

12 December 2020

Semiautomated assessment of loss of heterozygosity and replication error in tumors

1 reference

12 December 2020

Interphase cytogenetic analysis of mucinous ovarian neoplasms

1 reference

12 December 2020

Loss of heterozygosity on chromosome 18q in cohesive-type gastric cancer is associated with tumor progression and poor prognosis

1 reference

12 December 2020

Genomic alterations in fallopian tube carcinoma: comparison to serous uterine and ovarian carcinomas reveals similarity suggesting likeness in molecular pathogenesis

1 reference

12 December 2020

10.1016/S0002-9440(10)61670-7

Identifiers

DOI

1 reference

10 August 2017

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10 August 2017

1 reference