(Q35763305)

10 August 2017

title

Evolutionarily conserved residues at glucagon-like peptide-1 (GLP-1) receptor core confer ligand-induced receptor activation (English)

1 reference

10 August 2017

Mi Jin Moon

1

1 reference

10 August 2017

Hee Young Kim

2

1 reference

10 August 2017

Sumi Park

3

1 reference

10 August 2017

Dong-Kyu Kim

4

1 reference

10 August 2017

Eun Bee Cho

5

1 reference

10 August 2017

Cho Rong Park

6

1 reference

10 August 2017

Dong-Joo You

7

1 reference

10 August 2017

Jong-Ik Hwang

8

1 reference

10 August 2017

Kyungjin Kim

9

1 reference

10 August 2017

Han Choe

10

1 reference

10 August 2017

Jae Young Seong

11

1 reference

10 August 2017

language of work or name

English

0 references

publication date

21 November 2011

1 reference

Journal of Biological Chemistry

10 August 2017

published in

1 reference

10 August 2017

volume

287

1 reference

10 August 2017

issue

6

1 reference

10 August 2017

page(s)

3873-3884

1 reference

Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Tyr1 and Ile7 of Glucose-Dependent Insulinotropic Polypeptide (GIP) Confer Differential Ligand Selectivity toward GIP and Glucagon-like Peptide-1 Receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor: a region critical for biological activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Biology of incretins: GLP-1 and GIP

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Small-molecule agonists for the glucagon-like peptide 1 receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Characterization of glucagon-like peptide-1 receptor-binding determinants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Five out of six tryptophan residues in the N-terminal extracellular domain of the rat GLP-1 receptor are essential for its ability to bind GLP-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Glucagon and GLP-1 receptors: lessons from chimeric ligands and receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

GLP-1/GIP chimeric peptides define the structural requirements for specific ligand-receptor interaction of GLP-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

The amino terminal domain of the glucagon-like peptide-1 receptor is a critical determinant of subtype specificity.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Multiple extracellular loop domains contribute critical determinants for agonist binding and activation of the secretin receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Comparative protein modelling by satisfaction of spatial restraints

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors. Studies of chimeric receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

Glucagon.glucagon-like peptide I receptor chimeras reveal domains that determine specificity of glucagon binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

A Gastric Inhibitory Polypeptide II: The Complete Amino Acid Sequence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281735

The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro

12 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

Identification of a bioactive domain in the amino-terminus of glucose-dependent insulinotropic polypeptide (GIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

Structure-activity relationships of glucose-dependent insulinotropic polypeptide (GIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

chimeric peptides define the structural requirements for specific ligand-receptor interaction of GLP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276808

The C-terminus ends of secretin and VIP interact with the N-terminal domains of their receptors

21 January 2018

1 reference

12 December 2020

Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction

1 reference

12 December 2020

The isolated N-terminal extracellular domain of the glucagon-like peptide-1 (GLP)-1 receptor has intrinsic binding activity

1 reference

12 December 2020

Contribution of the second transmembrane helix of the secretin receptor to the positioning of secretin

1 reference

12 December 2020

1 reference

12 December 2020

Exchange of W39 by A within the N-terminal extracellular domain of the GLP-1 receptor results in a loss of receptor function

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.276808

1 reference

release_bg4jyye6crfq7m3r5z47imb5wi

10 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bg4jyye6crfq7m3r5z47imb5wi

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3281735

1 reference

10 August 2017

1 reference