(Q35802063)

10 August 2017

Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism (English)

1 reference

10 August 2017

Leishmania donovani

1 reference

Jan M Boitz

1

1 reference

10 August 2017

Rona Strasser

2

1 reference

10 August 2017

Charles U Hartman

3

1 reference

10 August 2017

Armando Jardim

4

1 reference

10 August 2017

Buddy Ullman

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

11 January 2012

1 reference

10 August 2017

14

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

10 August 2017

287

1 reference

10 August 2017

10

1 reference

10 August 2017

7626-7639

1 reference

The Role of Zn2+on the Structure and Stability of Murine Adenosine Deaminase

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Amplification of adenine phosphoribosyltransferase suppresses the conditionally lethal growth and virulence phenotype of Leishmania donovani mutants lacking both hypoxanthine-guanine and xanthine phosphoribosyltransferases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Structural and Metabolic Specificity of Methylthiocoformycin for Malarial Adenosine Deaminases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Structures of Substrate- and Inhibitor-Bound Adenosine Deaminase from a Human Malaria Parasite Show a Dramatic Conformational Change and Shed Light on Drug Selectivity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Conformational change of adenosine deaminase during ligand-exchange in a crystal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Aminohydrolases acting on adenine, adenosine and their derivatives

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Animal models for vaccine studies for visceral leishmaniasis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Studies on plant amylases: The effect of starch concentration upon the velocity of hydrolysis by the amylase of germinated barley

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Drug resistance in leishmaniasis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

The genome of the kinetoplastid parasite, Leishmania major

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

The Genome of the African Trypanosome Trypanosoma brucei

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Comparative genomics of trypanosomatid parasitic protozoa

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Immunopathogenesis of infection with the visceralizing Leishmania species

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Glycosomes: parasites and the divergence of peroxisomal purpose

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Chemotherapy of leishmaniasis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Biogenesis and function of peroxisomes and glycosomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Metabolic aspects of glycosomes in trypanosomatidae - new data and views

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Purine pathway enzymes in a cyst forming strain of Toxoplasma gondii

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Glycosylphosphatidylinositol biosynthetic enzymes are localized to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Visceral leishmaniasis in the BALB/c mouse: a comparison of the efficacy of a nonionic surfactant formulation of sodium stibogluconate with those of three proprietary formulations of amphotericin B.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase from Leishmania donovani

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Role of adenine deaminase in purine salvage and nitrogen metabolism and characterization of the ade gene in Bacillus subtilis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Purine and pyrimidine salvage pathways in Leishmania donovani

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

2'-deoxycoformycin. A new anticancer agent

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Nucleotide Biosynthesis from Preformed Purines in Mammalian Cells: Regulatory Mechanisms and Biological Significance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Genetic and physiological characterization of the purine salvage pathway in the archaebacterium Methanobacterium thermoautotrophicum Marburg

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Double targeted gene replacement for creating null mutants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Adenine deaminase and adenine utilization in Saccharomyces cerevisiae

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Stable propagation of cosmid sized human DNA inserts in an F factor based vector

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Degradation of purines and pyrimidines by microorganisms

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Adenine aminohydrolase: occurrence and possible significance in trypanosomid flagellates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Comparison of two Geographic Strains of Leishmania Donovani by Resistance of Mice to Superinfection *

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Adenine deaminase of a eukaryotic animal cell, Crithidia fasciculata

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Cloning and expression of the adenine phosphoribosyltransferase gene from Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Subcellular localization of adenine and xanthine phosphoribosyltransferases in Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Adenine deaminase activity of the yicP gene product of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

The nadA gene of Aspergillus nidulans, encoding adenine deaminase, is subject to a unique regulatory pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Adenosine kinase from Cryptosporidium parvum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Identification and overexpression of the A2 amastigote-specific protein in Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Virulent or avirulent (dhfr-ts-) Leishmania major elicit predominantly a type-1 cytokine response by human cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Characterization and purification of adenosine deaminase 1 from human and chicken liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Interaction of Leishmania PTS2 receptor peroxin 7 with the glycosomal protein import machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

IL-12 is required to maintain a Th1 response during Leishmania major infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

Single cell cloning of Leishmania parasites in purine-defined medium: isolation of drug-resistant variants.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

Human malaria parasite adenosine deaminase. Characterization in host enzyme-deficient erythrocyte culture

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293595

In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes

25 September 2018

2 references

https://api.crossref.org/works/10.1074%2FJBC.M111.307884

21 January 2018

12 December 2020

A Monophasic Medium for Cultivating Leishmania donovani in Large Numbers

1 reference

12 December 2020

Refined 2.5 A structure of murine adenosine deaminase at pH 6.0

1 reference

12 December 2020

Adenosine deaminase from human erythrocytes

1 reference

12 December 2020

Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages

1 reference

12 December 2020

Blasticidin resistance: a new independent marker for stable transfection of Leishmania

1 reference

12 December 2020

Purine phosphoribosyltransferases from Leishmania donovani

1 reference

12 December 2020

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1 reference

12 December 2020

Localization and Targeting of theLeishmania donovaniHypoxanthine-Guanine Phosphoribosyltransferase to the Glycosome

1 reference

12 December 2020

Catabolism of adenine nucleotides in suspension-cultured plant cells

1 reference

12 December 2020

Purine metabolism in Leishmania donovani amastigotes and promastigotes

1 reference

12 December 2020

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

12 December 2020

The properties of adenosine deaminase and adenosine nucleoside phosphorylase in extracts of Escherichia coli

1 reference

12 December 2020

Creation of homozygous mutants of Leishmania donovani with single targeting constructs

1 reference

12 December 2020

Genetic analysis of adenine metabolism in Leishmania donovani promastigotes. Evidence for diploidy at the adenine phosphoribosyltransferase locus

1 reference

12 December 2020

Adenine aminohydrolase. An investigation of specificity

1 reference

12 December 2020

Characterization of a mutant Leishmania donovani deficient in adenosine kinase activity

1 reference

12 December 2020

Purification and characterization of intestinal adenosine deaminase from mice

1 reference

12 December 2020

Two more independent selectable markers for stable transfection of Leishmania

1 reference

12 December 2020

A new spectrophotometric assay method of xanthine oxidase in crude tissue homogenate

1 reference

12 December 2020

High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.307884

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22238346

1 reference