(Q35865833)

English

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

scholarly article

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

H Ruffner

1

1 reference

Europe PubMed Central

10 August 2017

C A Joazeiro

2

1 reference

Europe PubMed Central

10 August 2017

D Hemmati

3

1 reference

Europe PubMed Central

10 August 2017

T Hunter

4

1 reference

Europe PubMed Central

10 August 2017

I M Verma

5

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 April 2001

1 reference

Europe PubMed Central

10 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

10 August 2017

98

1 reference

Europe PubMed Central

10 August 2017

5134-5139

1 reference

Europe PubMed Central

10 August 2017

9

1 reference

Europe PubMed Central

10 August 2017

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

RING for destruction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Genetic analysis of BRCA1 function in a defined tumor cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BRCA1 required for transcription-coupled repair of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BRCA1 protein products ... Functional motifs...

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Identification of the breast cancer susceptibility gene BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

Genetic analysis of breast cancer in the cancer and steroid hormone study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

11 July 2018

BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33176

24 September 2018

THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081068398

21 January 2018

Transcriptional activation by BRCA1

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081068398

21 January 2018

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11320250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/11320250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/11320250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.081068398

1 reference

Europe PubMed Central

10 August 2017

2001PNAS...98.5134R

0 references

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

ResearchGate publication ID

0 references

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