(Q35871793)

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A push-pull vaccine strategy using Toll-like receptor ligands, IL-15, and blockade of negative regulation to improve the quality and quantity of T cell immune responses

scientific article published on 21 November 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A push-pull vaccine strategy using Toll-like receptor ligands, IL-15, and blockade of negative regulation to improve the quality and quantity of T cell immune responses (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

toll-like receptor

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Jay A Berzofsky

1

object named as

Jay A Berzofsky

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

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publication date

21 November 2011

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

30

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

29

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

4323-4327

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

IL-15 ex vivo overcomes CD4+ T cell deficiency for the induction of human antigen-specific CD8+ T cell responses

1 reference

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Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques

1 reference

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Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

1 reference

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Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells

1 reference

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The role of NKT cells in tumor immunity

1 reference

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Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

27 July 2018

TGF-beta: a master of all T cell trades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

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NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis

1 reference

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CD1-restricted T cells and tumor immunity

1 reference

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The biology of NKT cells

1 reference

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Epitope enhancement of a CD4 HIV epitope toward the development of the next generation HIV vaccine

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Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

1 reference

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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

1 reference

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Modulating vaccine responses with dendritic cells and Toll-like receptors

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Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.

1 reference

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Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

27 July 2018

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

27 July 2018

A push-pull approach to maximize vaccine efficacy: abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

27 July 2018

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

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Innate immune recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

27 July 2018

High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319860

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Approaches to improve engineered vaccines for human immunodeficiency virus and other viruses that cause chronic infections

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Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

1 reference

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High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

1 reference

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Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions

1 reference

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Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides

1 reference

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Dendritic cells and the control of immunity

1 reference

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Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence

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Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

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Immunization with antigen and interleukin 2 in vivo overcomes Ir gene low responsiveness

1 reference

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The dendritic cell system and its role in immunogenicity

1 reference

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Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody

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Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma.

1 reference

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IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

1 reference

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Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid

1 reference

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Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis

1 reference

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A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

1 reference

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1 reference

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IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

1 reference

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Selective induction of high avidity CTL by altering the balance of signals from APC.

1 reference

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1 reference

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1 reference

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Designing peptide vaccines to broaden recognition and enhance potency

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.11.034

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1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.11.034

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Signals delivered through TCR instruct IL-12 receptor (IL-12R) expression: IL-12 and tumor necrosis factor-alpha synergize for IL-12R expression at low antigen dose

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.11.034

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Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.11.034

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NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2011.11.034

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22115635

12 December 2020

based on heuristic

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Identifiers

10.1016/J.VACCINE.2011.11.034

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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