(Q35879624)

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Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation

scientific article published on 13 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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Anna M Blom

4

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author name string

Jonatan Sjölander

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Gunilla T Westermark

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Erik Renström

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

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publication date

13 February 2012

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

10 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

10824-10833

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Complement: a key system for immune surveillance and homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Complement activation and inhibition: a delicate balance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Structural classification of toxic amyloid oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Association Between Low-Grade Systemic Inflammation and Type 2 Diabetes Mellitus Among Men and Women from the ATTICA Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Drug evaluation: the C5a receptor antagonist PMX-53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

T1DBase: integration and presentation of complex data for type 1 diabetes research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Complement. First of two parts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Concentration of the complement activation product, acylation-stimulating protein, is related to C-reactive protein in patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Inflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Charge-based binding of complement component C1q to the Alzheimer amyloid beta-peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Serum Amyloid P Component Binding to C4b-binding Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

The dissociation properties of native C1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein: sequence homology with the alpha chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Isolation of the Globular Region of the Subcomponent q of the C1 Component of Complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Isolation, by partial pepsin digestion, of the three collagen-like regions present in subcomponent Clq of the first component of human complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

11 July 2018

Unwinding fibril formation of medin, the peptide of the most common form of human amyloid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Complement activation by islet amyloid polypeptide (IAPP) and alpha-synuclein 112.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Complement activation in chromosome 13 dementias. Similarities with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Structural requirements for the complement regulatory activities of C4BP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322885

24 September 2018

Complement in inflammatory tissue damage and disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.244285

21 January 2018

Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relation of islet amyloid to the clinical type of diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C4b-binding protein in Alzheimer's disease: Binding to Aβ1–42 and to dead cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and radiolabeling of human C1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.244285

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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