(Q35911288)

English

Ranolazine stabilizes cardiac ryanodine receptors: a novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2.

scientific article published on 11 January 2012

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Ranolazine stabilizes cardiac ryanodine receptors: a novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2. (English)

1 reference

Europe PubMed Central

11 August 2017

torsades de pointes

1 reference

based on heuristic

inferred from title

Afterdepolarization

1 reference

based on heuristic

inferred from title

author name string

Ashish Parikh

1

1 reference

Europe PubMed Central

11 August 2017

Rajkumar Mantravadi

2

1 reference

Europe PubMed Central

11 August 2017

Dmitry Kozhevnikov

3

1 reference

Europe PubMed Central

11 August 2017

Michael A Roche

4

1 reference

Europe PubMed Central

11 August 2017

Yanping Ye

5

1 reference

Europe PubMed Central

11 August 2017

Laura J Owen

6

1 reference

Europe PubMed Central

11 August 2017

Jose Luis Puglisi

7

1 reference

Europe PubMed Central

11 August 2017

Jonathan J Abramson

8

1 reference

Europe PubMed Central

11 August 2017

Guy Salama

9

1 reference

Europe PubMed Central

11 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

11 January 2012

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

9

1 reference

Europe PubMed Central

11 August 2017

953-960

1 reference

Europe PubMed Central

11 August 2017

6

1 reference

Europe PubMed Central

11 August 2017

Designing calcium release channel inhibitors with enhanced electron donor properties: stabilizing the closed state of ryanodine receptor type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Electrophysiologic basis for the antiarrhythmic actions of ranolazine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Calcium oscillations and T-wave lability precede ventricular arrhythmias in acquired long QT type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Ranolazine antagonizes the effects of increased late sodium current on intracellular calcium cycling in rat isolated intact heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

The effect of ranolazine on maintaining sinus rhythm in patients with resistant atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Rapid kinetic interactions of ranolazine with HERG K+ current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Evaluation of a novel anti-ischemic agent in acute coronary syndromes: design and rationale for the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-elevation acute coronary syndromes (MERLIN)-TIMI 36 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Electrophysiologic properties and antiarrhythmic actions of a novel antianginal agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Delayed afterdepolarizations in heart muscle: mechanisms and relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Cellular mechanisms of early afterdepolarizations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Direct measurement of L-type Ca2+ window current in heart cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

11 July 2018

Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

24 September 2018

Simultaneous optical mapping of intracellular free calcium and action potentials from Langendorff perfused hearts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

24 September 2018

Antitorsadogenic effects of ({+/-})-N-(2,6-dimethyl-phenyl)-(4[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine (ranolazine) in anesthetized rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

24 September 2018

Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

24 September 2018

Ca2+-activated ryanodine binding: mechanisms of sensitivity and intensity modulation by Mg2+, caffeine, and adenine nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335957

24 September 2018

Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous maps of optical action potentials and calcium transients in guinea-pig hearts: mechanisms underlying concordant alternans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid calcium release from cardiac sarcoplasmic reticulum vesicles is dependent on Ca2+ and is modulated by Mg2+, adenine nucleotide, and calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: evidence for an indirect mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/22245792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.HRTHM.2012.01.010

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

ResearchGate publication ID

0 references

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