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A unifying model for mTORC1-mediated regulation of mRNA translation.
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Europe PubMed Central
PMCID
3347774
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
title
A unifying model for mTORC1-mediated regulation of mRNA translation
(English)
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3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
author
Timothy C Wang
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4
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3347774
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
David M. Sabatini
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6
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3347774
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Nathanael Gray
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5
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Nathanael S Gray
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Europe PubMed Central
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3347774
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31 January 2020
author name string
Carson C Thoreen
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1
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3347774
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31 January 2020
Lynne Chantranupong
series ordinal
2
1 reference
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Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Heather R Keys
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3
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Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
language of work or name
English
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publication date
2 May 2012
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Europe PubMed Central
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3347774
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31 January 2020
published in
Nature
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3347774
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31 January 2020
volume
485
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Europe PubMed Central
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3347774
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retrieved
31 January 2020
page(s)
109-113
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3347774
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31 January 2020
issue
7396
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Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nature11083
0 references
cites work
mTOR: from growth signal integration to cancer, diabetes and ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Aligning short sequencing reads with Bowtie
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Mammalian microRNAs predominantly act to decrease target mRNA levels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Epithelial-mesenchymal transitions in development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
DBTSS provides a tissue specific dynamic view of Transcription Start Sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Mapping and quantifying mammalian transcriptomes by RNA-Seq
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
A second look at cellular mRNA sequences said to function as internal ribosome entry sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
DINAMelt web server for nucleic acid melting prediction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Upstream and downstream of mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
eIF-4E expression and its role in malignancies and metastases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
CONTACT INHIBITION, MACROMOLECULAR SYNTHESIS, AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Synthesis of the translational apparatus is regulated at the translational level
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
Identification of the long ubiquitin extension as ribosomal protein S27a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
2 October 2017
All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347774
retrieved
11 July 2018
Cap-assisted internal initiation of translation of histone H4
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22552098
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE11083
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NATURE11083
1 reference
stated in
Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Dimensions Publication ID
1053542503
0 references
PMCID
3347774
1 reference
stated in
Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PubMed ID
22552098
1 reference
stated in
Europe PubMed Central
PMCID
3347774
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22552098%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
ResearchGate publication ID
224887892
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