(Q35956348)

11 August 2017

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title

Oxidative stress in the pathogenesis of hepatic encephalopathy (English)

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11 August 2017

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ChEBI release 2020-05-28

Norenberg MD

1

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11 August 2017

Jayakumar AR

series ordinal

2

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11 August 2017

Rama Rao KV

series ordinal

3

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11 August 2017

1 December 2004

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11 August 2017

Metabolic Brain Disease

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11 August 2017

19

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11 August 2017

313-329

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11 August 2017

3-4

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https://scigraph.springernature.com/pub.10.1023/b:mebr.0000043978.91675.79

11 August 2017

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cites work

Effect of body temperature on brain edema and encephalopathy in the rat after hepatic devascularization.

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12 December 2020

Acute liver failure and hyperammonemia increase peripheral-type benzodiazepine receptor binding and pregnenolone synthesis in mouse brain

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12 December 2020

Gliotoxic action of glutamate on cultured astrocytes

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12 December 2020

Manganese neurotoxicity: a mechanistic hypothesis.

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12 December 2020

Cerebral energy metabolism in hepatic encephalopathy and hyperammonemia

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12 December 2020

THE INHIBITION IN VIVO OF CEREBRAL GLUTAMINE SYNTHETASE AND GLUTAMINE TRANSFERASE BY THE CONVULSANT METHIONINE SULFOXIMINE.

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12 December 2020

Manganese induces the mitochondrial permeability transition in cultured astrocytes

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12 December 2020

Manganese and chronic hepatic encephalopathy

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12 December 2020

Molecular and functional properties of mitochondrial benzodiazepine receptors

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12 December 2020

Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism

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12 December 2020

Protective effect of L-carnitine in ammonia-precipitated encephalopathy in the portacaval shunted rat.

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12 December 2020

EFFECT OF AN INHIBITOR OF GLUTAMINE SYNTHESIS (METHIONINE SULFOXIMINE) ON AMMONIA TOXICITY AND METABOLISM

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12 December 2020

Cerebral hyperemia and nitric oxide synthase in rats with ammonia-induced brain edema

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12 December 2020

Increased manganese concentrations in pallidum of cirrhotic patients

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12 December 2020

Excitotoxic mechanism of cell swelling in rat cerebral cortical slices treated acutely with ammonia

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12 December 2020

Morphologic effects of ammonia on primary astrocyte cultures. II. Electron microscopic studies

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12 December 2020

Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure

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12 December 2020

Pathophysiology of cerebral edema in fulminant hepatic failure.

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12 December 2020

Glutamine synthetase inhibition prevents cerebral oedema during hyperammonemia

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12 December 2020

Effect of ascorbic acid on hyperoxic rat astrocytes

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12 December 2020

Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia

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12 December 2020

Inhibition by polyunsaturated fatty acids of cell volume regulation and osmolyte fluxes in astrocytes

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12 December 2020

An in vitro model for analysis of oxidative death in primary mouse astrocytes.

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12 December 2020

Indomethacin normalizes intracranial pressure in acute liver failure: a twenty-three-year-old woman treated with indomethacin

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12 December 2020

Effect of temperature variation on toxicity and metabolism of ammonia in mice

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12 December 2020

Role of antioxidants and scavengers on argemone oil-induced toxicity in rats

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12 December 2020

Mitochondrial damage as a source of diseases and aging: a strategy of how to fight these

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12 December 2020

Ammonia-induced production of free radicals in primary cultures of rat astrocytes

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12 December 2020

Manganese uptake and efflux in cultured rat astrocytes

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12 December 2020

Taurine transport and cell volume regulation in a mammalian cell.

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12 December 2020

Mn2+ sequestration by mitochondria and inhibition of oxidative phosphorylation

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12 December 2020

Protective actions of L-carnitine and acetyl-L-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors

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12 December 2020

Ammonia-induced heme oxygenase-1 expression in cultured rat astrocytes and rat brain in vivo

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12 December 2020

Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices.

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12 December 2020

Effect of antioxidants on ammonia induced CNS-renal pathobiology in sheep.

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12 December 2020

Inhibition of postcardiac arrest brain protein oxidation by acetyl-L-carnitine

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12 December 2020

Glutamine Synthetase: Glial Localization in Brain

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12 December 2020

Regional differences in the capacity for ammonia removal by brain following portocaval anastomosis

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12 December 2020

Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

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12 December 2020

Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis.

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12 December 2020

Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

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12 December 2020

Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.

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12 December 2020

Sources of oxygen radicals in brain in acute ammonia intoxication in vivo

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12 December 2020

Alterations to glutathione and nicotinamide nucleotides during the mitochondrial permeability transition induced by peroxynitrite

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12 December 2020

Ammonia-induced alterations in the metabolism of glutamate and aspartate in neuronal perikarya and synaptosomes of rat cerebellum

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12 December 2020

The role of arachidonic acid and oxygen radical metabolites in the pathogenesis of vasogenic brain edema and astrocytic swelling

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12 December 2020

Hepatic encephalopathy

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12 December 2020

Effect of anisotonic cell-volume modulation on glutathione-S-conjugate release, t-butylhydroperoxide metabolism and the pentose-phosphate shunt in perfused rat liver

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12 December 2020

Concentrations of physiologically important metal ions in glial cells cultured from chick cerebral cortex.

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12 December 2020

The antioxidant action of taurine, hypotaurine and their metabolic precursors

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12 December 2020

Characterization of the peripheral-type benzodiazepine receptors in cultured astrocytes: evidence for multiplicity

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12 December 2020

The mitochondrial permeability transition

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12 December 2020

Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors

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12 December 2020

Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations

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12 December 2020

Metabolism of [U-13C5] glutamine in cultured astrocytes studied by NMR spectroscopy: first evidence of astrocytic pyruvate recycling.

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12 December 2020

Oxidative injury and other metabolic disorders in hepatic encephalopathy

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12 December 2020

The mitochondrial permeability transition.

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12 December 2020

Ascorbate inhibits edema in brain slices

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12 December 2020

Benzodiazepine-induced protein tyrosine nitration in rat astrocytes

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12 December 2020

Hyperammonaemia does not impair brain function in the absence of net glutamine synthesis

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12 December 2020

Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine

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12 December 2020

Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

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12 December 2020

The role of astrocytes in hepatic encephalopathy

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12 December 2020

New pathways of nitrogen excretion in inborn errors of urea synthesis

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12 December 2020

Glutamine as a pathogenic factor in hepatic encephalopathy.

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12 December 2020

On the origin of lipofuscin; the iron content of residual bodies, and the relation of these organelles to the lysosomal vacuome. A study on cultured human glial cells

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12 December 2020

Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes

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12 December 2020

Study of the hypothermia induced by methionine sulfoximine in the rat

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12 December 2020

Oxidative stress involves in astrocytic alterations induced by manganese

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12 December 2020

Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis.

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12 December 2020

Mitochondria, free radicals, and neurodegeneration

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12 December 2020

L-Carnitine in the treatment of mild or moderate hepatic encephalopathy.

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12 December 2020

Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis.

1 reference

12 December 2020

Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line

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12 December 2020

Effects of enhanced extracellular ammonia concentration on cultured mammalian retinal glial (Müller) cells

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12 December 2020

Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes

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12 December 2020

Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.

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12 December 2020

Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes

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12 December 2020

The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: relation to energy metabolism and glutamatergic neurotransmission.

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12 December 2020

Glutamine and glutamate--their central role in cell metabolism and function.

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12 December 2020

Portal-systemic encephalopathy: presence of basal ganglia lesions with high signal intensity on MR images.

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12 December 2020

A light and electron microscopic study of experimental portal-systemic (ammonia) encephalopathy. Progression and reversal of the disorder

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12 December 2020

Astrocyte swelling in liver failure: role of glutamine and benzodiazepines

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12 December 2020

Hydroxyl radical scavenging and antipsoriatic activity of benzoic acid derivatives.

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12 December 2020

Mechanism of action and value of N-acetylcysteine in the treatment of early and late acetaminophen poisoning: a critical review

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12 December 2020

Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis

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12 December 2020

Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration

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12 December 2020

Response of rat cerebral glycolytic enzymes to hyperammonemic states

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12 December 2020

Brain edema in liver failure: basic physiologic principles and management

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12 December 2020

Endotoxin-induced nitric oxide synthesis in the perfused rat liver: effects of L-arginine and ammonium chloride.

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12 December 2020

Cerebral edema and intracranial hypertension in acute liver failure: Distinct aspects of the same problem

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12 December 2020

Role of manganese in the pathogenesis of portal-systemic encephalopathy

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12 December 2020

Current theories on the pathogenesis of hepatic encephalopathy

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12 December 2020

Vasodilatory properties of mono-L-arginine-containing compounds.

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12 December 2020

Manganese augments nitric oxide synthesis in murine astrocytes: a new pathogenetic mechanism in manganism?

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12 December 2020

Ammonia and manganese increase arginine uptake in cultured astrocytes.

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12 December 2020

Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis

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12 December 2020

Oxidative stress in Ca(2+)-induced membrane permeability transition in brain mitochondria

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12 December 2020

Moderate hypothermia prevents cerebral hyperemia and increase in intracranial pressure in patients undergoing liver transplantation for acute liver failure

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12 December 2020

Cerebral blood flow and metabolism in fulminant liver failure.

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12 December 2020

NMDA receptor antagonists prevent acute ammonia toxicity in mice

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12 December 2020

Superoxide production and antioxidant enzymes in ammonia intoxication in rats.

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12 December 2020

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12 December 2020

Characterization of cystine uptake in cultured astrocytes

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12 December 2020

Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria

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12 December 2020

The peripheral benzodiazepine receptor and neurosteroids in hepatic encephalopathy.

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12 December 2020

Indomethacin in the management of elevated intracranial pressure: a review.

1 reference

12 December 2020

GeneChip analysis shows altered mRNA expression of transcripts of neurotransmitter and signal transduction pathways in the cerebral cortex of portacaval shunted rats.

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12 December 2020

Sodium benzoate in the treatment of acute hepatic encephalopathy: a double-blind randomized trial

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12 December 2020

Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals

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12 December 2020

Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication.

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12 December 2020

Astrocyte metabolism of [15N]glutamine: implications for the glutamine-glutamate cycle

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12 December 2020

Effect of ammonium ions on synaptic transmission in the mammalian central nervous system

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12 December 2020

Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system

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12 December 2020

Beta-oxidation of [1-14C]palmitic acid by mouse astrocytes in primary culture: effects of agents implicated in the encephalopathy of Reye's syndrome

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12 December 2020

The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders

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12 December 2020

Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure

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12 December 2020

Swelling, acidosis, and irreversible damage of glial cells from exposure to arachidonic acid in vitro.

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12 December 2020

Carnitine as a free radical scavenger in aging

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12 December 2020

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

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12 December 2020

Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy.

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12 December 2020

Effects of ammonia exposition on glioma cells: changes in cell volume and organic osmolytes studied by diffusion-weighted and high-resolution NMR spectroscopy

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12 December 2020

Hepatic encephalopathy: An update of pathophysiologic mechanisms

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12 December 2020

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

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12 December 2020

Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure

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12 December 2020

Blood/brain barrier and brain oedema in ammonia intoxication

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12 December 2020

Endogenous hydroperoxide formation, cell volume and cellular K+ balance in perfused rat liver

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12 December 2020

Ammonia neurotoxicity: role of the mitochondrial permeability transition

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12 December 2020

Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function

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12 December 2020

Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress

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12 December 2020

Increased nitric oxide synthase activities and L-[3H]arginine uptake in brain following portacaval anastomosis

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12 December 2020

Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria.

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12 December 2020

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

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12 December 2020

Ammonia stimulates the release of taurine from cultured astrocytes

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12 December 2020

Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier.

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12 December 2020

Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

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12 December 2020

Pyrrolidine dithiocarbamate protects against thioacetamide-induced fulminant hepatic failure in rats

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12 December 2020

Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure

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12 December 2020

Morphologic effects of ammonia on primary astrocyte cultures. I. Light microscopic studies

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12 December 2020

Effect of portacaval anastomosis on glutamine synthetase activities in liver, brain, and skeletal muscle

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12 December 2020

Glutamine-induced free radical production in cultured astrocytes

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12 December 2020

Brain edema and hepatic encephalopathy

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12 December 2020

10.1023/B:MEBR.0000043978.91675.79

Identifiers

DOI

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Dimensions Publication ID

11 August 2017

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