(Q35976901)

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Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion

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scholarly article

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Europe PubMed Central

11 August 2017

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Europe PubMed Central

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion (English)

1 reference

Europe PubMed Central

11 August 2017

1 reference

based on heuristic

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author name string

Michael J MacDonald

1

1 reference

Europe PubMed Central

11 August 2017

Leonard A Fahien

2

1 reference

Europe PubMed Central

11 August 2017

Laura J Brown

3

1 reference

Europe PubMed Central

11 August 2017

Noaman M Hasan

4

1 reference

Europe PubMed Central

11 August 2017

Julian D Buss

5

1 reference

Europe PubMed Central

11 August 2017

Mindy A Kendrick

6

1 reference

Europe PubMed Central

11 August 2017

publication date

1 January 2005

1 reference

Europe PubMed Central

11 August 2017

American Journal of Physiology - Endocrinology and Metabolism

1 reference

Europe PubMed Central

11 August 2017

288

1 reference

Europe PubMed Central

11 August 2017

E1-15

1 reference

Europe PubMed Central

11 August 2017

1

1 reference

Europe PubMed Central

11 August 2017

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Inhibition of glucose- and calcium-induced insulin secretion from betaTC3 cells by novel inhibitors of protein isoprenylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The stimulus-secretion coupling of glucose-induced insulin release. Thiol: disulfide balance in pancreatic islets

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Ca2+ channels and excitation-contraction coupling

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Coupling of voltage-dependent potassium channel inactivation and oxidoreductase active site of Kvbeta subunits.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Normal thyroid thermogenesis but reduced viability and adiposity in mice lacking the mitochondrial glycerol phosphate dehydrogenase

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Lethal hypoglycemic ketosis and glyceroluria in mice lacking both the mitochondrial and the cytosolic glycerol phosphate dehydrogenases

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Hexose metabolism in pancreatic islets: pyruvate carboxylase activity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Metabolic control of beta-cell function

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Activation of glutamate dehydrogenase by leucine and its nonmetabolizable analogue in rat brain synaptosomes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The succinate mechanism of insulin release

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Critical role for cataplerosis via citrate in glucose-regulated insulin release

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Distinguishing Features of Leucine and α-Ketoisocaproate Sensing in Pancreatic β-Cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Decreased pancreatic islet response to L-leucine in the spontaneously diabetic GK rat: enzymatic, metabolic and secretory data

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Multiple abnormalities in insulin responses to nonglucose nutrients in neonatally streptozotocin diabetic rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Structure of a voltage-dependent K+ channel beta subunit

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Hierarchy of the beta-cell signals controlling insulin secretion.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Novel roles for the rho subfamily of GTP-binding proteins in succinate-induced insulin secretion from betaTC3 cells: further evidence in support of the succinate mechanism of insulin release

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for a plasma membrane aldehyde reductase

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Activation of the KATPchannel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The export of metabolites from mitochondria and anaplerosis in insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Oscillations in activities of enzymes in pancreatic islet subcellular fractions induced by physiological concentrations of effectors

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Citrate Oscillates in Liver and Pancreatic Beta Cell Mitochondria and in INS-1 Insulinoma Cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Temperature and redox state dependence of native Kv2.1 currents in rat pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Respiratory, ionic, and functional effects of succinate esters in pancreatic islets.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Constitutive nitric oxide synthases in rat pancreatic islets: direct imaging of glucose-induced nitric oxide production in beta-cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Metabolic coupling factors in pancreatic beta-cell signal transduction

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

New insights into pancreatic beta-cell metabolic signaling in insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Pancreatic islet beta-cells transiently metabolize pyruvate

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Glucose-stimulated signaling pathways in biphasic insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Superoxide as a messenger of endothelial function.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Uptake of NADPH by Islet Secretion Granule Membranes1

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Regulation of the citric acid cycle in mammalian systems

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Nutrient modulation of palmitoylated 24-kilodalton protein in rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Phosphofructokinase isozymes in pancreatic islets and clonal beta-cells (INS-1).

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Comparative effects of monomethylsuccinate and glucose on insulin secretion from perifused rat islets.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00218.2004

21 January 2018

Identifiers

10.1152/AJPENDO.00218.2004

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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