(Q36118391)

12 August 2017

Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. (English)

1 reference

12 August 2017

Katrin Deinhardt

1

0 references

Giampietro Schiavo

stated as

Giampietro Schiavo

5

0 references

author name string

Otto Berninghausen

2

1 reference

12 August 2017

Hugh J Willison

3

1 reference

12 August 2017

Colin R Hopkins

4

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 July 2006

1 reference

12 August 2017

Journal of Cell Biology

1 reference

12 August 2017

174

1 reference

12 August 2017

459-471

1 reference

12 August 2017

3

1 reference

Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Clathrin-independent endocytosis of ubiquitinated cargos

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Endocytosis and retrograde axonal traffic in motor neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Adaptors for clathrin coats: structure and function.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Presynaptic receptor arrays for clostridial neurotoxins.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Endocytosis by random initiation and stabilization of clathrin-coated pits.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Cell biology of the presynaptic terminal.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

The journey of tetanus and botulinum neurotoxins in neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Clathrin-mediated endocytosis in AP-2-depleted cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Differential requirements for AP-2 in clathrin-mediated endocytosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Regulated portals of entry into the cell

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Curvature of clathrin-coated pits driven by epsin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Membrane traffic exploited by protein toxins.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Neuronal activity-dependent membrane traffic at the neuromuscular junction.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

On Trk for retrograde signaling.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Internalization of cholera toxin by different endocytic mechanisms.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Cholera toxin is found in detergent-insoluble rafts/domains at the cell surface of hippocampal neurons but is internalized via a raft-independent mechanism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Chimeric molecules employing horseradish peroxidase as reporter enzyme for protein localization in the electron microscope.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

How botulinum and tetanus neurotoxins block neurotransmitter release.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Clostridial neurotoxins: handling and action at the cellular and molecular level.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Stage-specific assays for coated pit formation and coated vesicle budding in vitro.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Calcium triggers calcineurin-dependent synaptic vesicle recycling in mammalian nerve terminals.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Anterograde and retrograde traffic between the rough endoplasmic reticulum and the Golgi complex.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Retrograde axonal transport of gangliosides and glycoproteins in the motoneurons of rat sciatic nerve.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064241

Dynamics and regulation of clathrin coats at specialized endocytic zones of dendrites and spines.

2 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Starting a new genetic system: lessons from bacteroides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

GM1-containing lipid rafts are depleted within clathrin-coated pits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Endocytosis and retrograde axonal traffic in motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200508170

21 January 2018

Identifiers

DOI

10.1083/JCB.200508170

1 reference

12 August 2017

1 reference

12 August 2017

1 reference