(Q36199753)

12 August 2017

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title

Silence of the transcripts: RNA interference in medicine (English)

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12 August 2017

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1

Sailen Barik

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12 August 2017

19 July 2005

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Journal of Molecular Medicine

12 August 2017

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12 August 2017

83

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12 August 2017

764-773

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12 August 2017

10

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https://scigraph.springernature.com/pub.10.1007/s00109-005-0690-0

12 August 2017

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cites work

Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0690-0

Strategies for retargeted gene delivery using vectors derived from lentiviruses.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-005-0690-0

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

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12 December 2020

RNA interference in mammalian cells by chemically-modified RNA.

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12 December 2020

Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference.

1 reference

12 December 2020

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

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12 December 2020

Induction of an interferon response by RNAi vectors in mammalian cells

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12 December 2020

Activation of the interferon system by short-interfering RNAs

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12 December 2020

CXCR4 regulates growth of both primary and metastatic breast cancer

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12 December 2020

Inducible shRNA expression for application in a prostate cancer mouse model

1 reference

12 December 2020

Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania

1 reference

12 December 2020

Protection from HIV-1 infection of primary CD4 T cells by CCR5 silencing is effective for the full spectrum of CCR5 expression.

1 reference

12 December 2020

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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12 December 2020

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

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12 December 2020

siRNA target site secondary structure predictions using local stable substructures

1 reference

12 December 2020

Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA.

1 reference

12 December 2020

Viruses and the type I interferon antiviral system: induction and evasion

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12 December 2020

Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA.

1 reference

12 December 2020

Lack of interferon response in animals to naked siRNAs

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12 December 2020

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

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12 December 2020

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

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12 December 2020

An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.

1 reference

12 December 2020

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

1 reference

12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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12 December 2020

Assembly and function of RNA silencing complexes

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12 December 2020

Picking a winner: new mechanistic insights into the design of effective siRNAs

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12 December 2020

An algorithm for selection of functional siRNA sequences.

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12 December 2020

Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

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12 December 2020

The prospect of silencing disease using RNA interference

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12 December 2020

Retroviral vectors: new applications for an old tool

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12 December 2020

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

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12 December 2020

Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences

1 reference

12 December 2020

RNA-dependent RNA polymerases, viruses, and RNA silencing

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12 December 2020

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

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12 December 2020

Paramyxovirus strategies for evading the interferon response

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12 December 2020

Inverse interference: how viruses fight the interferon system

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12 December 2020

The microRNA Registry

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12 December 2020

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

1 reference

12 December 2020

siRNAs: applications in functional genomics and potential as therapeutics

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12 December 2020

RNA interference targeting Fas protects mice from fulminant hepatitis

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12 December 2020

Establishment of conditional vectors for hairpin siRNA knockdowns

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12 December 2020

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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12 December 2020

Suppression of beta-1,3-glucanase transgene expression in homozygous plants

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12 December 2020

RNA interference in protozoan parasites

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12 December 2020

The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides

1 reference

12 December 2020

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

1 reference

12 December 2020

The functions of animal microRNAs

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12 December 2020

Mechanisms of gene silencing by double-stranded RNA

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12 December 2020

Stable suppression of tumorigenicity by virus-mediated RNA interference

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12 December 2020

ATP requirements and small interfering RNA structure in the RNA interference pathway

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12 December 2020

RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.

1 reference

12 December 2020

Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression

1 reference

12 December 2020

Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference

1 reference

12 December 2020

siRNA as a route to new cancer therapies

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12 December 2020

Induction and suppression of RNA silencing: insights from viral infections

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12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

12 December 2020

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

1 reference

12 December 2020

Tolerance for mutations and chemical modifications in a siRNA.

1 reference

12 December 2020

Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus

1 reference

12 December 2020

Crystal structure of Argonaute and its implications for RISC slicer activity

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12 December 2020

Purified Argonaute2 and an siRNA form recombinant human RISC

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12 December 2020

An expanding universe of noncoding RNAs

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12 December 2020

In vivo activity of nuclease-resistant siRNAs

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12 December 2020

Adenoviral vectors expressing siRNAs for discovery and validation of gene function

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12 December 2020

Rational siRNA design for RNA interference

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12 December 2020

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics

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12 December 2020

Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

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12 December 2020

Small interfering RNAs and antisense oligonucleotides for treatment of neurological diseases.

1 reference

12 December 2020

RNA interference and chemically modified small interfering RNAs

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12 December 2020

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

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12 December 2020

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

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12 December 2020

Total silencing by intron-spliced hairpin RNAs

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12 December 2020

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

1 reference

12 December 2020

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

1 reference

12 December 2020

Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines

1 reference

12 December 2020

Different delivery methods-different expression profiles

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12 December 2020

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

1 reference

12 December 2020

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

1 reference

12 December 2020

Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies

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12 December 2020

RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells

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12 December 2020

Determinants of interferon-stimulated gene induction by RNAi vectors

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12 December 2020

siRNA function in RNAi: a chemical modification analysis

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12 December 2020

Hematologic side effects of interferon and ribavirin therapy

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12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

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12 December 2020

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

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12 December 2020

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

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12 December 2020

Resistance of human hepatitis delta virus RNAs to dicer activity

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12 December 2020

The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region

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12 December 2020

Control of nonsegmented negative-strand RNA virus replication by siRNA.

1 reference

12 December 2020

Functional complementation of RNA interference mutants in trypanosomes

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12 December 2020

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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12 December 2020

Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

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12 December 2020

Synthetic shRNAs as potent RNAi triggers.

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12 December 2020

Genomewide view of gene silencing by small interfering RNAs

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12 December 2020

Asymmetry in the assembly of the RNAi enzyme complex

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12 December 2020

Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs

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12 December 2020

Selection and characterization of RNA interference-deficient trypanosomes impaired in target mRNA degradation.

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12 December 2020

An enhanced U6 promoter for synthesis of short hairpin RNA.

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12 December 2020

Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain

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12 December 2020

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

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12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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12 December 2020

Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi.

1 reference

12 December 2020

Highly branched HK peptides are effective carriers of siRNA.

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12 December 2020

Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

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12 December 2020

Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis

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12 December 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

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12 December 2020

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

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12 December 2020

Targeting oncogenic fusion genes in leukemias and lymphomas by RNA interference

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12 December 2020

TROD: T7 RNAi Oligo Designer

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12 December 2020

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

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12 December 2020

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

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12 December 2020

Expression profiling reveals off-target gene regulation by RNAi

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12 December 2020

Inhibition of respiratory viruses by nasally administered siRNA.

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12 December 2020

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

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12 December 2020

Cationic lipids enhance siRNA-mediated interferon response in mice.

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12 December 2020

RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells

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12 December 2020

Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles

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12 December 2020

Sequence-specific inhibition of small RNA function

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12 December 2020

Development of gene-specific double-stranded RNA drugs

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12 December 2020

Argonaute2 is the catalytic engine of mammalian RNAi

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12 December 2020

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

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12 December 2020

Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

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12 December 2020

RNase III enzymes and the initiation of gene silencing

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12 December 2020

Exploring RNA interference as a therapeutic strategy for renal disease.

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12 December 2020

Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration

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12 December 2020

Specific inhibition of type I interferon signal transduction by respiratory syncytial virus

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12 December 2020

RNA interference and double-stranded-RNA-activated pathways

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12 December 2020

Revealing the world of RNA interference

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12 December 2020

10.1007/S00109-005-0690-0

Identifiers

DOI

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12 August 2017

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PubMed ID

16028076