(Q36201677)

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Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia

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scholarly article

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Europe PubMed Central

12 August 2017

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia (English)

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Europe PubMed Central

12 August 2017

lymphoblastic leukemia

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based on heuristic

inferred from title

Markus Müschen

38

object named as

Markus Müschen

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Europe PubMed Central

12 August 2017

object named as

Janetta J Bijl

24

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Natalya Goloviznina

object named as

Natalya A Goloviznina

7

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Dirk Baumjohann

object named as

Dirk Baumjohann

5

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object named as

Bill H Chang

37

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object named as

Thomas A Milne

36

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object named as

Brian J Druker

34

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Elisabeth Paietta

27

object named as

Elisabeth Paietta

1 reference

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12 August 2017

Stephen P Hunger

29

object named as

Stephen P Hunger

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12 August 2017

author name string

Huimin Geng

1

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12 August 2017

Christian Hurtz

2

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Kyle B Lenz

3

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Zhengshan Chen

4

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Sarah Thompson

6

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Wei-Yi Chen

8

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Jianya Huan

9

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Dorian LaTocha

10

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Erica Ballabio

11

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Gang Xiao

12

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Jae-Woong Lee

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Anne Deucher

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Zhongxia Qi

15

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Eugene Park

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Chuanxin Huang

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Rahul Nahar

18

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Soo-Mi Kweon

19

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Seyedmehdi Shojaee

20

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Lai N Chan

21

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Jingwei Yu

22

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Steven M Kornblau

23

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B Hilda Ye

25

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K Mark Ansel

26

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Ari Melnick

28

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Peter Kurre

30

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Jeffrey W Tyner

31

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Mignon L Loh

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Robert G Roeder

33

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Jan A Burger

35

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12 August 2017

language of work or name

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publication date

1 March 2015

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12 August 2017

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27

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409-425

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3

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12 August 2017

PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma

1 reference

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1 October 2017

New insights into pre-BCR and BCR signalling with relevance to B cell malignancies

1 reference

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BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint

1 reference

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Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia

1 reference

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Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma

1 reference

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SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas

1 reference

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1 October 2017

Targeting pathological B cell receptor signalling in lymphoid malignancies

1 reference

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Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

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Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

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A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

1 reference

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1 October 2017

SYK inhibition and response prediction in diffuse large B-cell lymphoma

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Structure of Human SMYD2 Protein Reveals the Basis of p53 Tumor Suppressor Methylation

1 reference

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1 October 2017

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition

1 reference

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1 October 2017

The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.

1 reference

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1 October 2017

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

1 reference

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1 October 2017

BCL6 is critical for the development of a diverse primary B cell repertoire

1 reference

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1 October 2017

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Tyrosine kinase inhibition in diffuse large B-cell lymphoma: molecular basis for antitumor activity and drug resistance of dasatinib.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

B-cell development fails in the absence of the Pbx1 proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

1 reference

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1 October 2017

Isotype-switched immunoglobulin genes with a high load of somatic hypermutation and lack of ongoing mutational activity are prevalent in mediastinal B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1 reference

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Clonal selection and learning in the antibody system

1 reference

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1 October 2017

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

1 October 2017

Lambda 5, a new light-chain-related locus selectively expressed in pre-B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4618684

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Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Ibrutinib in relapsed chronic lymphocytic leukemia

1 reference

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12 December 2020

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Identifiers

10.1016/J.CCELL.2015.02.003

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Europe PubMed Central

12 August 2017

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Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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