(Q36210257)

12 August 2017

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title

Aurora kinases: shining lights on the therapeutic horizon? (English)

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12 August 2017

1

Paul D Andrews

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PubMed ID

16049526

12 August 2017

language of work or name

English

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publication date

1 July 2005

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12 August 2017

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12 August 2017

24

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12 August 2017

5005-5015

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12 August 2017

32

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208752

12 August 2017

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cites work

Mitotic mechanics: the auroras come into view

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

The cellular geography of aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Survivin is required for stable checkpoint activation in taxol-treated HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Requirements for the destruction of human Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Issues and progress with protein kinase inhibitors for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Chromosome segregation and genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Cdc20 associates with the kinase aurora2/Aik

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

The mechanism of spindle assembly: functions of Ran and its target TPX2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Chromatin-associated Protein Phosphatase 1 Regulates Aurora-B and Histone H3 Phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

The spindle checkpoint: structural insights into dynamic signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

The role of chromosomal instability in tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Pathways of apoptotic and non-apoptotic death in tumour cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

21 January 2018

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Emerging classes of protein-protein interaction inhibitors and new tools for their development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Architecture of the budding yeast kinetochore reveals a conserved molecular core

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Cell death by mitotic catastrophe: a molecular definition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

TACC1-chTOG-Aurora A protein complex in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Regulation ofXenopusAurora A Activation by TPX2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Molecular analysis of kinetochore-microtubule attachment in budding yeast.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Microtubules, microtubule-interfering agents and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Unconventional Motoring: An Overview of the Kin C and Kin I Kinesins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Aneuploidy and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Chromosomal passengers: the four-dimensional regulation of mitotic events

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Cell division and cell survival in the absence of survivin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Aurora-A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208752

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208752

1 reference

12 August 2017

1 reference

PubMed ID

16049526