(Q36227971)

12 August 2017

12 references

23 March 2019

8 September 2019

12 October 2019

19 October 2019

18 October 2019

3 November 2019

20 November 2019

15 December 2019

26 August 2020

20 October 2022

23 October 2022

25 October 2022

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade (English)

1 reference

human immunodeficiency virus infectious disease

12 August 2017

10 references

23 March 2019

8 September 2019

12 October 2019

19 October 2019

18 October 2019

3 November 2019

20 November 2019

15 December 2019

1 July 2020

26 August 2020

regulation of gene expression

1 reference

8 September 2019

1 reference

12 October 2019

Retroviridae infectious disease

1 reference

19 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

3 November 2019

1 reference

20 November 2019

1 reference

15 December 2019

1 reference

1 July 2020

1 reference

26 August 2020

3

Rafi Ahmed

1 reference

12 August 2017

1

Gordon J Freeman

1 reference

12 August 2017

4

Arlene H Sharpe

1 reference

12 August 2017

E John Wherry

2

1 reference

PMCID

2118103

12 August 2017

language of work or name

English

0 references

publication date

25 September 2006

1 reference

PMCID

2118103

Journal of Experimental Medicine

12 August 2017

2 October 2006

13 references

23 March 2019

8 September 2019

12 October 2019

19 October 2019

18 October 2019

3 November 2019

20 November 2019

15 December 2019

1 July 2020

26 August 2020

20 October 2022

23 October 2022

25 October 2022

14 references

12 August 2017

23 March 2019

8 September 2019

12 October 2019

19 October 2019

18 October 2019

3 November 2019

20 November 2019

15 December 2019

1 July 2020

26 August 2020

20 October 2022

23 October 2022

25 October 2022

203

1 reference

12 August 2017

2223-2227

1 reference

12 August 2017

10

1 reference

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

The PD-1-PD-L pathway in immunological tolerance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Restoring function in exhausted CD8 T cells during chronic viral infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

T cells and viral persistence: lessons from diverse infections

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

1 October 2017

The B7 family revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Memory CD8 T-cell differentiation during viral infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Viral immune evasion due to persistence of activated T cells without effector function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118103

PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20061800

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20061800

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20061800

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17000870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17000870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Blockade of the interaction between PD-1 and PD-L1 accelerates graft arterial disease in cardiac allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17000870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20061800

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

2118103