(Q36281480)

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Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation

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Europe PubMed Central

PMC publication ID

13 August 2017

Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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Sandhoff disease

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

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author name string

Stephanos Kyrkanides

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Sabine M Brouxhon

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ross H Tallents

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jen-nie H Miller

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

John A Olschowka

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

M Kerry O'Banion

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

4 August 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Neuroinflammation

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Europe PubMed Central

PMC publication ID

13 August 2017

9

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Europe PubMed Central

PMC publication ID

13 August 2017

186

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB-/- mouse model of neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Storage solutions: treating lysosomal disorders of the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

beta-hexosaminidase lentiviral vectors: transfer into the CNS via systemic administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

30 September 2017

Molecular pathophysiology in Tay-Sachs and Sandhoff diseases as revealed by gene expression profiling

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-186

21 January 2018

TNF alpha and IL-1beta mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-9-186

21 January 2018

Intraperitoneal inoculation of Sandhoff mouse neonates with an HIV-1 based lentiviral vector exacerbates the attendant neuroinflammation and disease phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458890

22 September 2018

The transport of lysosomal enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22863301

12 December 2020

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10.1186/1742-2094-9-186

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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release_5htrsxlzqbarta6loyb6l2eeha

1 reference

https://api.fatcat.wiki/v0/release/5htrsxlzqbarta6loyb6l2eeha

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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