(Q36293973)

13 August 2017

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title

Genetic epidemiology and public health: hope, hype, and future prospects (English)

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13 August 2017

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1

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13 August 2017

5

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13 August 2017

Sarah Lewis

3

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Anna Hansell

object named as

Anna L Hansell

series ordinal

4

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Shah Ebrahim

series ordinal

2

object named as

Shah Ebrahim

1 reference

13 August 2017

Paul R Burton

6

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PubMed ID

16243094

13 August 2017

language of work or name

English

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publication date

1 October 2005

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13 August 2017

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13 August 2017

366

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13 August 2017

1484-1498

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13 August 2017

9495

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Pharmacogenetics: potential for individualized drug therapy through genetics

13 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Using pharmacogenetics to improve drug safety and efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Moving towards individualized medicine with pharmacogenomics

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Fibrinogen, C-reactive protein and coronary heart disease: does Mendelian randomization suggest the associations are non-causal?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: Mendelian randomization and gene-environment interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: development of Mendelian randomization: from hypothesis test to 'Mendelian deconfounding'

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: Katan's remarkable foresight: genes and causality 18 years on.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Mendelian randomization: prospects, potentials, and limitations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Epidemiological methods for studying genes and environmental factors in complex diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Homocysteine and coronary heart disease in the Caerphilly cohort: a 10 year follow up

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The new genetics in clinical practice

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Shattuck lecture--medical and societal consequences of the Human Genome Project.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Problems of reporting genetic associations with complex outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetic associations in large versus small studies: an empirical assessment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The International HapMap Project

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The complex interplay among factors that influence allelic association.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Neurodevelopment, neuroplasticity, and new genes for schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetics of Inflammatory Bowel Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Molecular genetic risk screening

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Key concepts in genetic epidemiology

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Laboratory standards and guidelines for population-based cystic fibrosis carrier screening.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Cystic fibrosis gene testing a challenge: experts say widespread use is creating unnecessary risks

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Prenatal screening for cystic fibrosis: an early report card

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Prenatal screening for cystic fibrosis: past, present and future

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Population screening for cystic fibrosis: knowledge and emotional consequences 18 months later

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Long-term cognitive and emotional impact of genetic testing for carriers of cystic fibrosis: the effects of test result and gender.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Incorrect recall of residual risk three years after carrier screening for cystic fibrosis: a comparison of two-step and couple screening.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Population screening for cystic fibrosis in Western Australia: community response

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Psychological and social impact of carrier screening for cystic fibrosis among pregnant woman--a pilot study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Experiences in molecular-based prenatal screening for Ashkenazi Jewish genetic diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Finnish Disease Heritage I: characteristics, causes, background

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Dissecting a population genome for targeted screening of disease mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Population genetic screening programmes: principles, techniques, practices, and policies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetic hemochromatosis, a Celtic disease: is it now time for population screening?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Strategies for early diagnosis of haemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Practice guideline development task force of the College of American Pathologists. Hereditary hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

1998 ASHG presidential address. Making genomic medicine a reality

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetic testing for cardiovascular disease susceptibility: a useful clinical management tool or possible misinformation?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Familial risk and genetic susceptibility for breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Estimating the survival benefits gained from providing national cancer genetic services to women with a family history of breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Ryanodine receptor mutations in malignant hyperthermia and central core disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Scientific and ethical aspects of genetic screening of workers for cancer risk: The case of the n-acetyltransferase phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genomic profiling to promote a healthy lifestyle: not ready for prime time

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetic evaluation for coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Clustering of risk factors and social class in childhood and adulthood in British women's heart and health study: cross sectional analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Can family history be used as a tool for public health and preventive medicine?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The family history--more important than ever

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetics and personalised medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetics of Drug Metabolising Enzymes: Importance for Personalised Medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetics goes genomic

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetics of HMG-CoA reductase inhibitors: exploring the potential for genotype-based individualization of coronary heart disease management

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Pharmacogenetic study of statin therapy and cholesterol reduction

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Epidemiology faces its limits.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Reflections on the limitations to epidemiology

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: hormone replacement therapy and coronary heart disease: four lessons

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: The rough world of nutritional epidemiology: Does dietary fibre prevent large bowel cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Vitamin E consumption and the risk of coronary heart disease in men.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Effect of supplemental vitamin E for the prevention and treatment of cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: Mendelian randomization--an update on its use to evaluate allogeneic stem cell transplantation in leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Osteoporosis, Intestinal Lactase Deficiency and Low Dietary Calcium Intake

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Lactase deficiency: prevalence in osteoporosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

N-Acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Hypothesis: is low prenatal vitamin D a risk-modifying factor for schizophrenia?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Cancer prevention and diet: help from single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The role of genetic polymorphisms in environmental health

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Apolipoprotein E isoforms, serum cholesterol, and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Commentary: the concept of 'Mendelian Randomization'.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Shaking the tree: mapping complex disease genes with linkage disequilibrium

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Association of C-Reactive Protein With Blood Pressure and Hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Validity of self-report in alcoholism research: results of a Veterans Administration Cooperative Study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Mendelian randomisation: a new spin or real progress?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Canalization: a molecular genetic perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Principles for the buffering of genetic variation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genetically reduced antioxidative protection and increased ischemic heart disease risk: The Copenhagen City Heart Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Case-control association studies for the genetics of complex respiratory diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Association study designs for complex diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Parameters for reliable results in genetic association studies in common disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

How many diseases does it take to map a gene with SNPs?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Replication validity of genetic association studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Candidate-gene approaches for studying complex genetic traits: practical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Searching for genetic determinants in the new millennium

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Large upward bias in estimation of locus-specific effects from genomewide scans

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The case for a US prospective cohort study of genes and environment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Design, objectives, and lessons from a pilot 25 year follow up re-survey of survivors in the Whitehall study of London Civil Servants

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

1 reference

7 January 2021

Amount of DNA in plasma and cancer risk: A prospective study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The emergence of epidemiology in the genomics age.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genomics as a probe for disease biology

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Population screening in the age of genomic medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Genomic Priorities and Public Health

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Locating gene–environment interaction: at the intersections of genetics and public health

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

Translating biomedical research to the bedside: a national crisis and a call to action

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

The future of genetic studies of complex human diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2967601-5

7 January 2021

10.1016/S0140-6736(05)67601-5

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16243094