(Q36301775)

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Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.

scientific article published on 3 November 2007

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scholarly article

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9 January 2020

Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment (English)

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9 January 2020

molecular design

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2

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9 January 2020

author name string

Mala L Radhakrishnan

1

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publication date

3 November 2007

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9 January 2020

number of pages

17

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Journal of Physical Chemistry B

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9 January 2020

111

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9 January 2020

13419-13435

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9 January 2020

47

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9 January 2020

All-atom empirical potential for molecular modeling and dynamics studies of proteins

1 reference

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The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

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Optimization of binding electrostatics: charge complementarity in the barnase-barstar protein complex.

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Structural basis of carbohydrate recognition by lectin II from Ulex europaeus, a protein with a promiscuous carbohydrate-binding site

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Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions

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Energy functions for protein design

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Cutting edge: identification of novel T cell epitopes in Lol p5a by computational prediction.

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Molecular mimicry and immune-mediated diseases

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Effects of salt bridges on protein structure and design.

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A promiscuous binding surface: crystal structure of the IIA domain of the glucose-specific permease from Mycoplasma capricolum

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VMD: visual molecular dynamics

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A priori inference of cross reactivity for drug-targeted kinases.

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Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies

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Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

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Discovery of promiscuous HLA-II-restricted T cell epitopes with TEPITOPE.

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1 reference

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1 reference

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1 reference

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Identifiers

10.1021/JP074285E

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17979267%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17979267%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17979267%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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