(Q36342355)

13 August 2017

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title

Lymphangiogenesis in development and human disease (English)

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13 August 2017

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Kari Alitalo

1

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Tatiana V Petrova

series ordinal

3

object named as

Tatiana V Petrova

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13 August 2017

2

Tuomas Tammela

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PubMed ID

16355212

13 August 2017

language of work or name

English

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publication date

1 December 2005

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13 August 2017

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13 August 2017

438

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13 August 2017

946-953

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13 August 2017

7070

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https://scigraph.springernature.com/pub.10.1038/nature04480

13 August 2017

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cites work

New insights into the biology and pathology of the cutaneous lymphatic system

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7 January 2021

Lymphatic vasculature development

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7 January 2021

Molecular lymphangiogenesis: new players.

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7 January 2021

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

A model for gene therapy of human hereditary lymphedema

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Proteolytic processing regulates receptor specificity and activity of VEGF-C.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor C induces angiogenesis in vivo.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Hepatocyte growth factor promotes lymphatic vessel formation and function

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Prox1 function is required for the development of the murine lymphatic system

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Biology of the lymphatic marker LYVE-1 and applications in research into lymphatic trafficking and lymphangiogenesis

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Genesis and pathogenesis of lymphatic vessels

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Chylous ascites: a collective review

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Eph receptors and ephrin ligands. essential mediators of vascular development.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Research perspectives in inherited lymphatic disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Molecular characterization of lymphatic endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

https://api.crossref.org/works/10.1038%2FNATURE04480

1 reference

7 January 2021

Gene transfer as a tool to induce therapeutic vascular growth

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https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphangiogenic gene therapy with minimal blood vascular side effects

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Angiopoietin-1 protects the adult vasculature against plasma leakage.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphangiogenesis and cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Pathology: cancer cells compress intratumour vessels.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphatic metastasis in the absence of functional intratumor lymphatics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Chemokines in neoplastic progression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Visualization of lymphatic vessels through NF- B activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Mannose receptor is a novel ligand for L-selectin and mediates lymphocyte binding to lymphatic endothelium

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

FOXC2 haploinsufficient mice are a model for human autosomal dominant lymphedema-distichiasis syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Abnormal lymphatic development in trisomy 16 mouse embryos precedes nuchal edema.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphangioblasts in the avian wing bud

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04480

7 January 2021

Identifiers

DOI

10.1038/NATURE04480

1 reference

13 August 2017

1 reference

PubMed ID

16355212