(Q36371743)

13 August 2017

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells (English)

1 reference

13 August 2017

0 references

1

1 reference

13 August 2017

Hamsa Puthalakath

3

0 references

Philippe Bouillet

object named as

Philippe Bouillet

2

0 references

David M Tarlinton

object named as

David M Tarlinton

5

0 references

Andreas Strasser

object named as

Andreas Strasser

6

0 references

author name string

Yuekang Xu

4

1 reference

PMCID

2194219

13 August 2017

language of work or name

English

0 references

publication date

29 September 2003

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

198

1 reference

13 August 2017

1119-1126

1 reference

13 August 2017

7

1 reference

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

BH3-Only proteins-essential initiators of apoptotic cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1 or CrmA-sensitive caspases but is defective in both MRL-+/+ and MRL-lpr/lpr mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Fas ligand-induced apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

BCL-2 family members and the mitochondria in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Dissection of pathways leading to antigen receptor-induced and Fas/CD95-induced apoptosis in human B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Bim: a novel member of the Bcl-2 family that promotes apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Receptor editing: an approach by autoreactive B cells to escape tolerance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Receptor editing in self-reactive bone marrow B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Negative selection of lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Peripheral deletion of self-reactive B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Reduced life span of anergic self-reactive B cells in a double-transgenic model

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2194219

Induction of self-tolerance in mature peripheral B lymphocytes

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20030411

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20030411

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20030411

B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14517273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of the lpr mutation on elimination and inactivation of self-reactive B cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14517273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14517273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20030411

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

2194219