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p53 mutations increase resistance to ionizing radiation
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
title
p53 mutations increase resistance to ionizing radiation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
author name string
Lee JM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
Bernstein A
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
language of work or name
English
0 references
publication date
1 June 1993
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
volume
90
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
page(s)
5742-5746
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stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
issue
12
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
cites work
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30 September 2017
Meth A fibrosarcoma cells express two transforming mutant p53 species
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30 September 2017
Checkpoints: controls that ensure the order of cell cycle events
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PubMed Central
reference URL
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30 September 2017
Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Wild-type p53 can inhibit oncogene-mediated focus formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
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30 September 2017
The p53 proto-oncogene can act as a suppressor of transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
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30 September 2017
Molecular and cellular events of T cell development
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PubMed Central
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30 September 2017
High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Functional inactivation of genes by dominant negative mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
A potential transcriptional activation element in the p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
p53 functions as a cell cycle control protein in osteosarcomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Suppression of human colorectal carcinoma cell growth by wild-type p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Tumor suppressor genes: the p53 and retinoblastoma sensitivity genes and gene products
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
p53: oncogene or anti-oncogene?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Identification of p53 as a sequence-specific DNA-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
The p53 tumour suppressor gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Participation of p53 protein in the cellular response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Cancer. p53, guardian of the genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Genealogy of Cancer in a Family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
30 September 2017
Transmission of in-vitro radioresistance in a cancer-prone family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Participation of p53 cellular tumour antigen in transformation of normal embryonic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Oncogenes in radioresistant, noncancerous skin fibroblasts from a cancer-prone family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Immortalization of rat embryo fibroblasts by the cellular p53 oncogene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Programmed death of autoreactive thymocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Presence of a potent transcription activating sequence in the p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
28 June 2018
Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
21 September 2018
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
21 September 2018
Characteristics of the immunocompetent cells in the mouse thymus: cell population changes during cortisone-induced atrophy and subsequent regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46798
retrieved
21 September 2018
High levels of p53 protein in UV-irradiated normal human skin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8516323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8516323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Wild-type p53 activates transcription in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8516323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8516323
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.90.12.5742
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
ADS bibcode
1993PNAS...90.5742L
0 references
PMCID
46798
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
PubMed ID
8516323
1 reference
stated in
Europe PubMed Central
PMCID
46798
retrieved
13 August 2017
ResearchGate publication ID
14683643
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