(Q36374960)

13 August 2017

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title

Notch signalling in vertebrate neural development (English)

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Spiros Artavanis-Tsakonas

13 August 2017

series ordinal

2

object named as

Spyros Artavanis-Tsakonas

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13 August 2017

Angeliki Louvi

1

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PubMed ID

16429119

13 August 2017

language of work or name

English

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publication date

1 February 2006

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Nature Reviews Neuroscience

13 August 2017

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13 August 2017

7

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13 August 2017

93-102

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13 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/nrn1847

13 August 2017

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cites work

The Analysis of a Case of Continuous Variation in Drosophila by a Study of Its Linkage Relations

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Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster

21 January 2018

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Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

21 January 2018

1 reference

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

21 January 2018

1 reference

Early events in insect neurogenesis. II. The role of cell interactions and cell lineage in the determination of neuronal precursor cells

21 January 2018

1 reference

Glycosylation regulates Notch signalling.

21 January 2018

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Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

21 January 2018

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Nuclear access and action of notch in vivo

21 January 2018

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

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The suppressor of hairless protein participates in notch receptor signaling.

21 January 2018

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The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers

21 January 2018

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The ins and outs of notch signaling

21 January 2018

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The LIN-12/Notch signaling pathway and its regulation

21 January 2018

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Notch signaling and inherited disease syndromes

21 January 2018

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Notch signaling in development and disease.

21 January 2018

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Arabidopsis genome: life without notch.

21 January 2018

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Notch signalling controls pancreatic cell differentiation

21 January 2018

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Notch1 and notch2 have opposite effects on embryonal brain tumor growth

21 January 2018

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F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

21 January 2018

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DNER acts as a neuron-specific Notch ligand during Bergmann glial development

21 January 2018

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CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

21 January 2018

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SCORE: a computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data. Site clustering over random expectation.

21 January 2018

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Mice lacking both presenilin genes exhibit early embryonic patterning defects

21 January 2018

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

21 January 2018

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Dosage-sensitive requirement for mouse Dll4 in artery development

21 January 2018

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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

21 January 2018

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The roles of receptor and ligand endocytosis in regulating Notch signaling

21 January 2018

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LIN-12/Notch signaling: lessons from worms and flies

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

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Notch signaling: control of cell communication and cell fate

21 January 2018

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Regulation of Notch signalling by non-visual beta-arrestin

21 January 2018

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Genetic control of cell fate specification in Drosophila peripheral nervous system

21 January 2018

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Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos.

21 January 2018

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Xotch inhibits cell differentiation in the Xenopus retina

21 January 2018

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An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye.

21 January 2018

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Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis

21 January 2018

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Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain

21 January 2018

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The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain

21 January 2018

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Radial glial identity is promoted by Notch1 signaling in the murine forebrain

21 January 2018

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

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The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates

21 January 2018

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Regulation of neuronal diversity in the Xenopus retina by Delta signalling

21 January 2018

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rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells

21 January 2018

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Neuronal potential and lineage determination by neural stem cells

21 January 2018

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Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity.

21 January 2018

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Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

21 January 2018

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Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells.

21 January 2018

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Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate

21 January 2018

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

21 January 2018

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Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process

21 January 2018

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Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease.

21 January 2018

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Nuclear Notch1 signaling and the regulation of dendritic development

21 January 2018

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Notch1 inhibits neurite outgrowth in postmitotic primary neurons.

21 January 2018

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Processing of the notch ligand delta by the metalloprotease Kuzbanian

21 January 2018

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Down-regulation of Delta by proteolytic processing

21 January 2018

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Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

21 January 2018

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kuzbanian-mediated cleavage of Drosophila Notch

21 January 2018

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Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia

21 January 2018

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A role for Abl in Notch signaling.

21 January 2018

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Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing.

21 January 2018

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Involvement of Notch signaling in hippocampal synaptic plasticity

21 January 2018

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Notch signaling in the mammalian central nervous system: insights from mouse mutants

21 January 2018

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Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

21 January 2018

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CADASIL: a critical look at a Notch disease

21 January 2018

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Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

21 January 2018

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The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

21 January 2018

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Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization.

21 January 2018

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Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

21 January 2018

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Meningioma transcript profiles reveal deregulated Notch signaling pathway

21 January 2018

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Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

21 January 2018

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

21 January 2018

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Fringe, Notch, and making developmental boundaries.

21 January 2018

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Modulation of Notch Signaling During Somitogenesis

21 January 2018

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A new developmental compartment in the forebrain regulated by Lunatic fringe

21 January 2018

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Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain.

21 January 2018

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Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

21 January 2018

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Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

21 January 2018

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Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

21 January 2018

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Molecular pathways needed for regeneration of spinal cord and muscle in a vertebrate.

21 January 2018

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LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

21 January 2018

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Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

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EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output.

21 January 2018

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Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

21 January 2018

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Signalling downstream of activated mammalian Notch

21 January 2018

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Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

21 January 2018

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Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells

21 January 2018

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Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

21 January 2018

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Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

21 January 2018

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Notch receptor activation inhibits oligodendrocyte differentiation.

21 January 2018

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Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

21 January 2018

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Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling

21 January 2018

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Identification and expression of a novel family of bHLH cDNAs related to Drosophila hairy and enhancer of split

21 January 2018

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HERP, a new primary target of Notch regulated by ligand binding

21 January 2018

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The expression of the neurogenic locus Notch during the postembryonic development of Drosophila melanogaster and its relationship to mitotic activity.

21 January 2018

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Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth.

21 January 2018

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Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila.

21 January 2018

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Control of cell proliferation in the Drosophila eye by Notch signaling.

21 January 2018

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Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing.

21 January 2018

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Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

21 January 2018

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The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

21 January 2018

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Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

21 January 2018

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Presenilin 1 in migration and morphogenesis in the central nervous system

21 January 2018

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Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons

21 January 2018

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Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation.

21 January 2018

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The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2.

21 January 2018

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Delta-Notch signaling regulates oligodendrocyte specification.

21 January 2018

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Central nervous system myelination in mice with deficient expression of Notch1 receptor

21 January 2018

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Notch1 control of oligodendrocyte differentiation in the spinal cord

21 January 2018

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

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Mutations in NOTCH1 cause aortic valve disease

21 January 2018

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Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

21 January 2018

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Mutations in the human Jagged1 gene are responsible for Alagille syndrome

21 January 2018

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Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

21 January 2018

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Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype

21 January 2018

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Mutated MESP2 causes spondylocostal dysostosis in humans

21 January 2018

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Analysis of a Gene in Drosophila

21 January 2018

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Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

31 March 2020

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Progenitors resume generating neurons after temporary inhibition of neurogenesis by Notch activation in the mammalian cerebral cortex

31 March 2020

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Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 activity with both immature and terminally differentiated cells

31 March 2020

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The expression and function of Notch pathway genes in the developing rat eye

31 March 2020

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Maintenance of neuroepithelial progenitor cells by Delta–Notch signalling in the embryonic chick retina

31 March 2020

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The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina.

31 March 2020

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Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation

31 March 2020

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Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord

31 March 2020

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Contact-dependent inhibition of cortical neurite growth mediated by notch signaling

31 March 2020

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Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

31 March 2020

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Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

31 March 2020

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Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis

31 March 2020

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p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRN1847

1 reference

13 August 2017

1 reference

PubMed ID

16429119