(Q36380617)

English

Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice

scientific article published in September 1997

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

13 August 2017

Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice (English)

1 reference

Europe PubMed Central

13 August 2017

author name string

K Salojin

1

1 reference

Europe PubMed Central

13 August 2017

J Zhang

2

1 reference

Europe PubMed Central

13 August 2017

M Cameron

3

1 reference

Europe PubMed Central

13 August 2017

B Gill

4

1 reference

Europe PubMed Central

13 August 2017

G Arreaza

5

1 reference

Europe PubMed Central

13 August 2017

A Ochi

6

1 reference

Europe PubMed Central

13 August 2017

T L Delovitch

7

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 September 1997

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

13 August 2017

186

1 reference

Europe PubMed Central

13 August 2017

887-897

1 reference

Europe PubMed Central

13 August 2017

6

1 reference

Europe PubMed Central

13 August 2017

Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

T cell antigen receptor signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Models of T cell anergy: is there a common molecular mechanism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Insulin dependent diabetes mellitus in the non-obese diabetic mouse: a disease mediated by T cell anergy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Ligation of the T-cell antigen receptor (TCR) induces association of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Signal transduction in T lymphocytes using a conditional allele of Sos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Stimulation of phospholipase C-gamma 1 membrane association by epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

The Son of sevenless Gene Product: a Putative Activator of Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

30 September 2017

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

28 June 2018

Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

28 June 2018

Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

28 June 2018

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199053

21 September 2018

Ligation of the T-cell Antigen Receptor (TCR) Induces Association of hSos1, ZAP-70, Phospolipase C- 1, and Other Phosphoproteins with Grb2 and the -Chain of the TCR

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.6.887

21 January 2018

Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon Activation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.6.887

21 January 2018

Epidermal Growth Factor Receptor Targeting Prevents Uncoupling of the Grb2-SOS Complex

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.6.887

21 January 2018

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.6.887

21 January 2018

Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocked Ras activation in anergic CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered Thymic and Peripheral T-Lymphocyte Repertoire Preceding Onset of Diabetes in NOD Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of clonal anergy by oral administration of staphylococcal enterotoxin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.186.6.887

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

ResearchGate publication ID

0 references

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