(Q36430140)

14 August 2017

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title

ITAM-mediated tonic signalling through pre-BCR and BCR complexes (English)

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14 August 2017

John G Monroe

1

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14 August 2017

1 April 2006

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Nature Reviews Immunology

14 August 2017

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14 August 2017

6

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14 August 2017

283-294

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14 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/nri1808

14 August 2017

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cites work

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains

21 January 2018

1 reference

Evidence for a preformed transducer complex organized by the B cell antigen receptor

21 January 2018

1 reference

The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion

21 January 2018

1 reference

The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice

21 January 2018

1 reference

Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases

21 January 2018

1 reference

Regulation of B-cell fate by antigen-receptor signals

21 January 2018

1 reference

Catalytic specificity of phosphotyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display

21 January 2018

1 reference

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide

21 January 2018

1 reference

Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI

21 January 2018

1 reference

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

21 January 2018

1 reference

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

21 January 2018

1 reference

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

21 January 2018

1 reference

CD45: a critical regulator of signaling thresholds in immune cells

21 January 2018

1 reference

Positive and negative regulation of Src-family membrane kinases by CD45.

21 January 2018

1 reference

CD19, CD21, and CD22: multifaceted response regulators of B lymphocyte signal transduction

21 January 2018

1 reference

The role of CD22 and other inhibitory co-receptors in B-cell activation

21 January 2018

1 reference

Immunoreceptor tyrosine-based inhibition motif-bearing receptors regulate the immunoreceptor tyrosine-based activation motif-induced activation of immune competent cells

21 January 2018

1 reference

A role for lipid rafts in B cell antigen receptor signaling and antigen targeting

21 January 2018

1 reference

Floating the raft hypothesis: lipid rafts play a role in immune cell activation

21 January 2018

1 reference

The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling

21 January 2018

1 reference

Independent trafficking of Ig-alpha/Ig-beta and mu-heavy chain is facilitated by dissociation of the B cell antigen receptor complex

21 January 2018

1 reference

Ig-independent Ig beta expression on the surface of B lymphocytes after B cell receptor aggregation.

21 January 2018

1 reference

TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.

21 January 2018

1 reference

The surrogate light chain in mouse B-cell development

21 January 2018

1 reference

B cell development: signal transduction by antigen receptors and their surrogates.

21 January 2018

1 reference

Antibody regulation of B cell development

21 January 2018

1 reference

Signal transduction by the B cell antigen receptor and its coreceptors

21 January 2018

1 reference

CD19 function in early and late B cell development. II. CD19 facilitates the pro-B/pre-B transition

21 January 2018

1 reference

Basal Igalpha/Igbeta signals trigger the coordinated initiation of pre-B cell antigen receptor-dependent processes

21 January 2018

1 reference

Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

21 January 2018

1 reference

Surrogate light chain-mediated interaction of a soluble pre-B cell receptor with adherent cell lines

21 January 2018

1 reference

The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling

21 January 2018

1 reference

Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition

21 January 2018

1 reference

The variable, C(H)1, C(H)2 and C(H)3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice.

21 January 2018

1 reference

Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein

21 January 2018

1 reference

Development of B cells expressing surface immunoglobulin molecules that lack V(D)J-encoded determinants in the avian embryo bursa of fabricius

21 January 2018

1 reference

Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis

21 January 2018

1 reference

Ig alpha/Ig beta complexes generate signals for B cell development independent of selective plasma membrane compartmentalization.

21 January 2018

1 reference

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer.

21 January 2018

1 reference

Deletion of immunoglobulin beta in developing B cells leads to cell death

21 January 2018

1 reference

Latent membrane protein 2A, a viral B cell receptor homologue, induces CD5+ B-1 cell development

21 January 2018

1 reference

B cell receptor signal strength determines B cell fate.

21 January 2018

1 reference

BAFF mediates survival of peripheral immature B lymphocytes

21 January 2018

1 reference

Modification of ligand-independent B cell receptor tonic signals activates receptor editing in immature B lymphocytes

21 January 2018

1 reference

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

21 January 2018

1 reference

Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival

21 January 2018

1 reference

Monomeric and oligomeric complexes of the B cell antigen receptor

21 January 2018

1 reference

The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer

21 January 2018

1 reference

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

21 January 2018

1 reference

Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization

21 January 2018

1 reference

Negative regulation of immunoreceptor signaling

21 January 2018

1 reference

Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction.

21 January 2018

1 reference

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

21 January 2018

1 reference

Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase

21 January 2018

1 reference

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

21 January 2018

1 reference

Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling

21 January 2018

1 reference

A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP

21 January 2018

1 reference

B cells acquire antigen from target cells after synapse formation

21 January 2018

1 reference

The strength of receptor signaling is centrally controlled through a cooperative loop between Ca2+ and an oxidant signal.

21 January 2018

1 reference

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

21 January 2018

1 reference

Hydrogen peroxide as second messenger in lymphocyte activation

21 January 2018

1 reference

Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils

21 January 2018

1 reference

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop

21 January 2018

1 reference

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

21 January 2018

1 reference

Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130

21 January 2018

1 reference

SHPS-1, a multifunctional transmembrane glycoprotein

21 January 2018

1 reference

Signal regulation by family conspiracy

21 January 2018

1 reference

Systematic identification of immunoreceptor tyrosine-based inhibitory motifs in the human proteome

21 January 2018

1 reference

The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction

21 January 2018

1 reference

Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway

21 January 2018

1 reference

Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

The K1 protein of Kaposi's sarcoma-associated herpesvirus activates the Akt signaling pathway

21 January 2018

1 reference

Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene

21 January 2018

1 reference

Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

Epstein-Barr virus: 40 years on

21 January 2018

1 reference

Mouse mammary tumor virus and the immune system

21 January 2018

1 reference

Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis

21 January 2018

1 reference

Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt.

21 January 2018

1 reference

Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signaling

21 January 2018

1 reference

The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors.

21 January 2018

1 reference

MMTV Env encodes an ITAM responsible for transformation of mammary epithelial cells in three-dimensional culture

21 January 2018

1 reference

Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.

21 January 2018

1 reference

T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression

21 January 2018

1 reference

Fidelity in planar cell polarity signalling.

21 January 2018

1 reference

The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye.

21 January 2018

1 reference

Ligand-independent tonic signaling in B-cell receptor function

21 January 2018

1 reference

The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo

21 January 2018

1 reference

Bovine leukemia virus gp30 transmembrane (TM) protein is not tyrosine phosphorylated: examining potential interactions with host tyrosine-mediated signaling

21 January 2018

1 reference

Thermodynamic Study of the Binding of the Tandem-SH2 Domain of the Syk Kinase to a Dually Phosphorylated ITAM Peptide: Evidence for Two Conformers†

21 January 2018

1 reference

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors

21 January 2018

1 reference

Positive selection of natural autoreactive B cells

31 March 2020

1 reference

Cutting edge: B cell receptor signals regulate BLyS receptor levels in mature B cells and their immediate progenitors

31 March 2020

1 reference

Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop

31 March 2020

1 reference

CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing

31 March 2020

1 reference

Point mutation of a tyrosine in the linker region of Syk results in a gain of function

31 March 2020

1 reference

Signal transduction by reactive oxygen species in non-phagocytic cells.

31 March 2020

1 reference

Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor

31 March 2020

1 reference

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1808

1 reference

PubMed ID

16557260

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16557260