(Q36434963)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

4 references

20 July 2020

20 December 2020

3 October 2022

Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

20 December 2020

chronic obstructive pulmonary disease

4 references

20 July 2020

20 December 2020

3 October 2022

2 references

20 July 2020

3 October 2022

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Ingel K Demedts

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Tine Demoor

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Guy F Joos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Guy G Brusselle

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

30 March 2006

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

20 July 2020

20 December 2020

3 October 2022

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

20 July 2020

20 December 2020

3 October 2022

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

18 January 2020

copyright license

3 references

20 July 2020

20 December 2020

https://scigraph.springernature.com/pub.10.1186/1465-9921-7-53

3 October 2022

0 references

0 references

cites work

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Local and systemic inflammation in chronic obstructive pulmonary disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Matrix metalloproteinases in asthma and COPD.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Apoptosis as a therapeutic target for the treatment of lung disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Burden and clinical features of chronic obstructive pulmonary disease (COPD).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Caspase-12 and ER-stress-mediated apoptosis: the story so far.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Alveolar wall apoptosis causes lung destruction and emphysematous changes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Chronic obstructive pulmonary disease. 5: systemic effects of COPD

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Cytotoxic T lymphocytes: all roads lead to death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Matrix metalloproteinases: they're not just for matrix anymore!

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Growth factors can influence cell growth and survival through effects on glucose metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Granulocyte apoptosis and its role in the resolution and control of lung inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Perforin-independent CD8(+) T-cell-mediated cytotoxicity of alveolar epithelial cells is preferentially mediated by tumor necrosis factor-alpha: relative insensitivity to Fas ligand

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Two CD95 (APO-1/Fas) signaling pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

An induced proximity model for caspase-8 activation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Survival factors, intracellular signal transduction, and the activation of endonucleases in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

An increase of soluble Fas, an inhibitor of apoptosis, associated with progression of COPD.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Peripheral muscle weakness in patients with chronic obstructive pulmonary disease.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Elevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of COPD.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

The development of emphysema in cigarette smoke-exposed mice is strain dependent.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Vascular endothelial growth factor and the risk of smoking-related COPD.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

Programmed cell death and apoptosis: origins of the theory.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1501017

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

21 September 2018

1 reference

12 December 2020

Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD

1 reference

12 December 2020

CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease

1 reference

12 December 2020

Circulating levels of soluble Fas ligand and soluble Fas in patients with chronic obstructive pulmonary disease

1 reference

12 December 2020

Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema

1 reference

12 December 2020

Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema

1 reference

12 December 2020

Increased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPD

1 reference

12 December 2020

Osteoporosis in chronic obstructive pulmonary disease

1 reference

12 December 2020

Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease

1 reference

12 December 2020

Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma

1 reference

12 December 2020

Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells

1 reference

12 December 2020

Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants

1 reference

12 December 2020

Correlation of lung surface area to apoptosis and proliferation in human emphysema

1 reference

12 December 2020

Identifiers

DOI

10.1186/1465-9921-7-53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16571143%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference