Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36481817)
Watch
English
Reduced PDZ interactions of rescued ΔF508CFTR increases its cell surface mobility.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
title
Reduced PDZ interactions of rescued ΔF508CFTR increases its cell surface mobility
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author
Gergely L Lukacs
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
Alan S Verkman
series ordinal
3
object named as
Alan S Verkman
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author name string
Cathleen D Valentine
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
Peter M Haggie
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
language of work or name
English
0 references
publication date
31 October 2012
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
volume
287
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
page(s)
43630-43638
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
issue
52
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
cites work
CFTR: folding, misfolding and correcting the ΔF508 conformational defect.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Confinement of β(1)- and β(2)-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Protein quality control at the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Peripheral protein quality control removes unfolded CFTR from the plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Mechanisms for rescue of correctable folding defects in CFTRDelta F508.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Quantitative microscopy: protein dynamics and membrane organisation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
One step at a time: endoplasmic reticulum-associated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
New concepts in synaptic biology derived from single-molecule imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
CFTR function and prospects for therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Single-particle tracking of membrane protein diffusion in a potential: simulation, detection, and application to confined diffusion of CFTR Cl- channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Cargo regulates clathrin-coated pit dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Cystic fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
COOH-terminal truncations promote proteasome-dependent degradation of mature cystic fibrosis transmembrane conductance regulator from post-Golgi compartments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
A PDZ-interacting domain in CFTR is an apical membrane polarization signal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
30 September 2017
A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
28 June 2018
Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
28 June 2018
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
28 June 2018
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527949
retrieved
21 September 2018
New insights into cystic fibrosis: molecular switches that regulate CFTR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M112.421172
retrieved
21 January 2018
Identifiers
DOI
10.1074/JBC.M112.421172
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PMCID
3527949
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PubMed ID
23115232
1 reference
stated in
Europe PubMed Central
PMCID
3527949
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit