(Q36493258)

14 August 2017

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title

Canalization of development by microRNAs (English)

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14 August 2017

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2

Noam Shomron

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14 August 2017

Eran Hornstein

1

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PubMed ID

16736020

14 August 2017

language of work or name

English

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publication date

1 June 2006

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14 August 2017

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14 August 2017

38 Suppl

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14 August 2017

S20-4

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https://scigraph.springernature.com/pub.10.1038/ng1803

14 August 2017

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Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

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Principles of microRNA-target recognition

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The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.

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A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

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The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.

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Dicer is essential for mouse development

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T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer

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MicroRNAs regulate brain morphogenesis in zebrafish

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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

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Aberrant T cell differentiation in the absence of Dicer.

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Dicer function is essential for lung epithelium morphogenesis

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Combinatorial microRNA target predictions

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MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

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Structure and function of the feed-forward loop network motif

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MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision

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The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development

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The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings

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A pancreatic islet-specific microRNA regulates insulin secretion

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Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

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A brain-specific microRNA regulates dendritic spine development

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Cell-type-specific signatures of microRNAs on target mRNA expression

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CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

21 January 2018

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7 January 2021

A model relating gene replicas and gene repression to phenotypic expression and variability

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7 January 2021

The evolutionary genetics of canalization

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7 January 2021

microRNA target predictions across seven Drosophila species and comparison to mammalian targets

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7 January 2021

Cryptic genetic variation is enriched for potential adaptations

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7 January 2021

Effect of polymorphism in the Drosophila regulatory gene Ultrabithorax on homeotic stability.

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7 January 2021

Developmental robustness.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG1803

1 reference

PubMed ID

16736020

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16736020