(Q36504877)

14 August 2017

1 reference

title

Alternative splicing and RNA selection pressure--evolutionary consequences for eukaryotic genomes (English)

1 reference

alternative mRNA splicing, via spliceosome

14 August 2017

1 reference

Yi Xing

1

1 reference

PubMed ID

16770337

14 August 2017

Christopher Lee

series ordinal

2

1 reference

14 August 2017

13 June 2006

1 reference

14 August 2017

Nature Reviews Genetics

1 reference

14 August 2017

7

1 reference

14 August 2017

499-509

1 reference

14 August 2017

7

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg1896

14 August 2017

0 references

cites work

An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA.

1 reference

21 January 2018

1 reference

A genomic view of alternative splicing

21 January 2018

1 reference

Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform

21 January 2018

1 reference

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays

21 January 2018

1 reference

Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles

21 January 2018

1 reference

Selecting for functional alternative splices in ESTs

21 January 2018

1 reference

Computational comparative analyses of alternative splicing regulation using full-length cDNA of various eukaryotes

21 January 2018

1 reference

Low conservation of alternative splicing patterns in the human and mouse genomes.

21 January 2018

1 reference

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

21 January 2018

1 reference

Conservation of human alternative splice events in mouse

21 January 2018

1 reference

Species-specific variation of alternative splicing and transcriptional initiation in six eukaryotes.

21 January 2018

1 reference

Alternative pre-mRNA splicing: the logic of combinatorial control

21 January 2018

1 reference

Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity

21 January 2018

1 reference

The Sequence of the Human Genome

21 January 2018

1 reference

Alternative splicing: increasing diversity in the proteomic world

21 January 2018

1 reference

YIDB: the Yeast Intron DataBase.

21 January 2018

1 reference

Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast

21 January 2018

1 reference

Alternative splicing and genome complexity

21 January 2018

1 reference

The origin of new genes: glimpses from the young and old

21 January 2018

1 reference

Duplication and divergence: the evolution of new genes and old ideas

21 January 2018

1 reference

Changes in Alternative Splicing of Human and Mouse Genes Are Accompanied by Faster Evolution of Constitutive Exons

21 January 2018

1 reference

The evolving roles of alternative splicing

21 January 2018

1 reference

Alternative splicing and evolution

21 January 2018

1 reference

How did alternative splicing evolve?

21 January 2018

1 reference

Alu sequences in the coding regions of mRNA: a source of protein variability.

21 January 2018

1 reference

Transposable elements are found in a large number of human protein-coding genes

21 January 2018

1 reference

Alu-containing exons are alternatively spliced

21 January 2018

1 reference

The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons

21 January 2018

1 reference

From "junk" to gene: curriculum vitae of a primate receptor isoform gene

21 January 2018

1 reference

Alu-SINE exonization: en route to protein-coding function

21 January 2018

1 reference

Do transposable elements really contribute to proteomes?

21 January 2018

1 reference

An unappreciated role for RNA surveillance

21 January 2018

1 reference

Common exon duplication in animals and its role in alternative splicing

21 January 2018

1 reference

Origin of alternative splicing by tandem exon duplication.

21 January 2018

1 reference

Evolutionary convergence of alternative splicing in ion channels

21 January 2018

1 reference

Evolution of exon-intron structure and alternative splicing in fruit flies and malarial mosquito genomes.

21 January 2018

1 reference

Origin and evolution of new exons in rodents

21 January 2018

1 reference

Evolution of alternative splicing: deletions, insertions and origin of functional parts of proteins from intron sequences

21 January 2018

1 reference

Evolution of the exon-intron structure and alternative splicing of the MAGE-A family of cancer/testis antigens.

21 January 2018

1 reference

The complexity of alternative splicing of hagoromo mRNAs is increased in an explosively speciated lineage in East African cichlids

21 January 2018

1 reference

Messenger RNA surveillance and the evolutionary proliferation of introns

21 January 2018

1 reference

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

21 January 2018

1 reference

Cryptic genetic variation is enriched for potential adaptations

21 January 2018

1 reference

Negative selection pressure against premature protein truncation is reduced by alternative splicing and diploidy.

21 January 2018

1 reference

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

21 January 2018

1 reference

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

21 January 2018

1 reference

Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

21 January 2018

1 reference

Evolution of alternative splicing after gene duplication

21 January 2018

1 reference

The Ka/Ks ratio: diagnosing the form of sequence evolution

21 January 2018

1 reference

Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models

21 January 2018

1 reference

Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates.

21 January 2018

1 reference

Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences

21 January 2018

1 reference

A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes.

21 January 2018

1 reference

Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing

21 January 2018

1 reference

The K(A)/K(S) ratio test for assessing the protein-coding potential of genomic regions: an empirical and simulation study

21 January 2018

1 reference

Assessing the application of Ka/Ks ratio test to alternatively spliced exons

21 January 2018

1 reference

Recognition of unknown conserved alternatively spliced exons

21 January 2018

1 reference

Can RNA selection pressure distort the measurement of Ka/Ks?

21 January 2018

1 reference

Adjusting for selection on synonymous sites in estimates of evolutionary distance

21 January 2018

1 reference

Mammalian housekeeping genes evolve more slowly than tissue-specific genes.

21 January 2018

1 reference

Hearing silence: non-neutral evolution at synonymous sites in mammals

21 January 2018

1 reference

Ultraconserved Elements in the Human Genome

21 January 2018

1 reference

Intronic sequences flanking alternatively spliced exons are conserved between human and mouse

21 January 2018

1 reference

In NF1, CFTR, PER3, CARS and SYT7, alternatively included exons show higher conservation of surrounding intron sequences than constitutive exons

21 January 2018

1 reference

Characteristics and regulatory elements defining constitutive splicing and different modes of alternative splicing in human and mouse

21 January 2018

1 reference

Unusual intron conservation near tissue-regulated exons found by splicing microarrays

21 January 2018

1 reference

A non-EST-based method for exon-skipping prediction

21 January 2018

1 reference

A computational and experimental approach toward a priori identification of alternatively spliced exons

21 January 2018

1 reference

Identification and analysis of alternative splicing events conserved in human and mouse

21 January 2018

1 reference

Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines

21 January 2018

1 reference

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis

21 January 2018

1 reference

Emerging roles of BRCA1 alternative splicing

21 January 2018

1 reference

Structure and evolution of the alternatively spliced fast troponin T isoform gene.

21 January 2018

1 reference

Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing

21 January 2018

1 reference

Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation

21 January 2018

1 reference

A combinatorial code for splicing silencing: UAGG and GGGG motifs

21 January 2018

1 reference

Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression

21 January 2018

1 reference

Genomic variants in exons and introns: identifying the splicing spoilers

21 January 2018

1 reference

The origin and evolution of model organisms

21 January 2018

1 reference

How prevalent is functional alternative splicing in the human genome?

21 January 2018

1 reference

Predictive identification of exonic splicing enhancers in human genes

21 January 2018

1 reference

Systematic identification and analysis of exonic splicing silencers.

21 January 2018

1 reference

Computational searches for splicing signals.

21 January 2018

1 reference

Computational definition of sequence motifs governing constitutive exon splicing.

21 January 2018

1 reference

Single nucleotide polymorphism-based validation of exonic splicing enhancers

21 January 2018

1 reference

Synonymous SNPs provide evidence for selective constraint on human exonic splicing enhancers

21 January 2018

1 reference

Biased codon usage near intron-exon junctions: selection on splicing enhancers, splice-site recognition or something else?

21 January 2018

1 reference

Cisrequirements for alternative splicing of the cardiac troponin T pre–mRNA

21 January 2018

1 reference

A stem structure in fibroblast growth factor receptor 2 transcripts mediates cell-type-specific splicing by approximating intronic control elements

21 January 2018

1 reference

A variable dinucleotide repeat in the CFTR gene contributes to phenotype diversity by forming RNA secondary structures that alter splicing

21 January 2018

1 reference

Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures

21 January 2018

1 reference

The iStem, a long-range RNA secondary structure element required for efficient exon inclusion in the Drosophila Dscam pre-mRNA.

21 January 2018

1 reference

Alternative splicing of type II procollagen exon 2 is regulated by the combination of a weak 5' splice site and an adjacent intronic stem-loop cis element

21 January 2018

1 reference

Influence of RNA secondary structure on the pre-mRNA splicing process

21 January 2018

1 reference

Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals

21 January 2018

1 reference

Evidence for the regulation of alternative splicing via complementary DNA sequence repeats.

21 January 2018

1 reference

Statistical evidence for conserved, local secondary structure in the coding regions of eukaryotic mRNAs and pre-mRNAs

21 January 2018

1 reference

Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.

21 January 2018

1 reference

Listening to silence and understanding nonsense: exonic mutations that affect splicing

21 January 2018

1 reference

The role of common single-nucleotide polymorphisms on exon 9 and exon 12 skipping in nonmutated CFTR alleles.

21 January 2018

1 reference

Are splicing mutations the most frequent cause of hereditary disease?

21 January 2018

1 reference

A maximum likelihood method for analyzing pseudogene evolution: implications for silent site evolution in humans and rodents

21 January 2018

1 reference

Nonclassical splicing mutations in the coding and noncoding regions of the ATM Gene: maximum entropy estimates of splice junction strengths

21 January 2018

1 reference

Linking C5 deficiency to an exonic splicing enhancer mutation

21 January 2018

1 reference

A mutation hotspot at the p14ARF splice site.

21 January 2018

1 reference

Lysinuric protein intolerance: identification and functional analysis of mutations of the SLC7A7 gene

21 January 2018

1 reference

The SR protein SC35 is responsible for aberrant splicing of the E1alpha pyruvate dehydrogenase mRNA in a case of mental retardation with lactic acidosis

21 January 2018

1 reference

Mild Pelizaeus-Merzbacher disease caused by a point mutation affecting correct splicing of PLP1 mRNA.

21 January 2018

1 reference

Tyrosinaemia type I--de novo mutation in liver tissue suppressing an inborn splicing defect

21 January 2018

1 reference

Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation.

21 January 2018

1 reference

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

1 reference

Missense, nonsense, and neutral mutations define juxtaposed regulatory elements of splicing in cystic fibrosis transmembrane regulator exon 9.

21 January 2018

1 reference

Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity

21 January 2018

1 reference

Regions of extreme synonymous codon selection in mammalian genes

21 January 2018

1 reference

Fast rate of evolution in alternatively spliced coding regions of mammalian genes.

21 January 2018

1 reference

Duplication, degeneration and subfunctionalization of the nested synapsin–Timp genes in Fugu

21 January 2018

1 reference

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

Evidence for Purifying Selection Against Synonymous Mutations in Mammalian Exonic Splicing Enhancers

21 January 2018

1 reference

Lessons from mutant globins

21 January 2018

1 reference

Alternative splicing of conserved exons is frequently species-specific in human and mouse

31 March 2020

1 reference

Initial sequencing and analysis of the human genome

31 March 2020

1 reference

Estimating rates of alternative splicing in mammals and invertebrates

31 March 2020

1 reference

Alternative splicing and gene duplication are inversely correlated evolutionary mechanisms

31 March 2020

1 reference

Evidence for purifying selection acting on silent sites in BRCA1

31 March 2020

1 reference

Purifying selection on silent sites -- a constraint from splicing regulation?

31 March 2020

1 reference

The evolution of an alternatively spliced exon in the alphaA-crystallin gene

31 March 2020

1 reference

beta-Tropomyosin pre-mRNA folding around a muscle-specific exon interferes with several steps of spliceosome assembly

31 March 2020

1 reference

A mutation-created novel intra-exonic pre-mRNA splice site causes constitutive activation of KIT in human gastrointestinal stromal tumors

31 March 2020

1 reference

Identification of novel type VII collagen gene mutations resulting in severe recessive dystrophic epidermolysis bullosa

31 March 2020

1 reference

APC germ-line mutations in southern Spanish patients with familial adenomatous polyposis: genotype-phenotype correlations and identification of eight novel mutations

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1896

1 reference

PubMed ID

16770337

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16770337