(Q36512697)

English

Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade

scientific article published on March 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Jharna Datta

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Sarmila Majumder

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Huban Kutay

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Tasneem Motiwala

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Wendy Frankel

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Robert Costa

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Hyuk C Cha

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Ormond A MacDougald

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Samson T Jacob

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Kalpana Ghoshal

10

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

1 March 2007

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

67

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

2736-2746

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

New therapies for hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

New aspects of diagnosis and therapy of hepatocellular carcinoma.

1 reference

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30 September 2017

Viral hepatitis and liver cancer: the case of hepatitis C.

1 reference

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30 September 2017

Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis

1 reference

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30 September 2017

Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity

1 reference

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30 September 2017

Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes

1 reference

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Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells

1 reference

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Mechanisms of disease: Inflammation and the origins of cancer

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Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors

1 reference

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30 September 2017

5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

1 reference

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DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2

1 reference

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30 September 2017

Environmental factors and risk for hepatocellular carcinoma

1 reference

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30 September 2017

Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity

1 reference

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30 September 2017

Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor

1 reference

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30 September 2017

Phosphorylation of C/EBPalpha inhibits granulopoiesis

1 reference

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30 September 2017

Metallothioneins in human tumors and potential roles in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

Molecular viral oncology of hepatocellular carcinoma

1 reference

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30 September 2017

Treatment of hepatocellular carcinoma: is there an optimal strategy?

1 reference

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30 September 2017

Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma

1 reference

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30 September 2017

Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals

1 reference

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30 September 2017

Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

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30 September 2017

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

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30 September 2017

The "metal transcription factor" MTF-1: biological facts and medical implications

1 reference

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30 September 2017

McBindall--a better name for CCAAT/enhancer binding proteins?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

Regulation of metallothionein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276570

30 September 2017

The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene

1 reference

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30 September 2017

Regulation of metallothionein gene expression by oxidative stress and metal ions

1 reference

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30 September 2017

The antioxidant function of metallothionein in the heart

1 reference

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30 September 2017

Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation

1 reference

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Glycogen synthase kinase 3 is an insulin-regulated C/EBPalpha kinase

1 reference

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30 September 2017

Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein

1 reference

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30 September 2017

Thiolate ligands in metallothionein confer redox activity on zinc clusters

1 reference

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30 September 2017

Gene expression profiles in normal and cancer cells

1 reference

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30 September 2017

Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

1 reference

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30 September 2017

Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens

1 reference

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30 September 2017

Immunohistochemical metallothionein expression in hepatocellular carcinoma: relation to tumor progression and chemoresistance to platinum agents

1 reference

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28 June 2018

Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice

1 reference

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Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

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Hypersusceptibility to cisplatin carcinogenicity in metallothionein-I/II double knockout mice: production of hepatocellular carcinoma at clinically relevant doses.

1 reference

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21 September 2018

Down-regulated expression of the CCAAT/enhancer binding protein alpha and beta genes in human hepatocellular carcinoma: a possible prognostic marker

1 reference

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21 September 2018

Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells

1 reference

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Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.

1 reference

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21 September 2018

Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation

1 reference

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Repeated cadmium exposures enhance the malignant progression of ensuing tumors in rats

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new diagnostic method for chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma based on serum metallothionein, copper, and zinc levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17363595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein overexpression suppresses hepatic hyperplasia induced by hepatitis B surface antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17363595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analysis of biliary tract lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17363595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17363595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-06-4433

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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