(Q36521196)

14 August 2017

1 reference

title

Functional consequences of NOD2 (CARD15) mutations (English)

1 reference

14 August 2017

2

Judy H Cho

1 reference

14 August 2017

Clara Abraham

1

1 reference

14 August 2017

1 July 2006

1 reference

Inflammatory Bowel Diseases

14 August 2017

1 reference

14 August 2017

12

1 reference

14 August 2017

641-650

1 reference

14 August 2017

7

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

14 August 2017

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

CARD15 mutations in Blau syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

CARD15 gene mutations in sarcoidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

CARD 15 gene mutations in sarcoidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Macrophage stimulation with Murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPbeta and STAT1: role of CD14 and Toll-like receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Reciprocal cross-talk between Nod2 and TAK1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Synthesis and antitumor activity of conjugates of muramyldipeptide, normuramyldipeptide, and desmuramylpeptides with acridine/acridone derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Structural requirements of synthetic muropeptides to synergize with lipopolysaccharide in cytokine induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Modulation of expression of class II MHC and CD40 molecules in murine B cells by various muramyl dipeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Stimulation of mouse resistance to bacterial infection with muramyl dipeptide glycoside

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Diverting intracellular trafficking of Salmonella to the lysosome through activation of the late endocytic Rab7 by intracellular delivery of muramyl dipeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Immune responses to Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches--a personal and historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2 and Crohn's disease: loss or gain of function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Perspectives: protein structure. Class-conscious TCR?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

War and peace at mucosal surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000225332.83861.5F

10.1097/01.MIB.0000225332.83861.5F

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16804402