(Q36544066)

14 August 2017

Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway (English)

1 reference

14 August 2017

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Li-Juan Deng

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Qun-Long Peng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Long-Hai Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Jun Xu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Jun-Shan Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Ying-Jie Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Zhen-Jian Zhuo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Li-Ping Hu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Wei-Min Chen

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Wen-Cai Ye

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Dong-Mei Zhang

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

0 references

publication date

13 October 2015

1 reference

14 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

34258-34275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4741450/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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30 September 2017

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DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1.

30 September 2017

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PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways

30 September 2017

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Epigenetic therapy as a novel approach in hepatocellular carcinoma.

30 September 2017

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Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells.

30 September 2017

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Toad glandular secretions and skin extractions as anti-inflammatory and anticancer agents

30 September 2017

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Quantitative determination of arenobufagin in rat plasma by ultra fast liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study

30 September 2017

1 reference

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Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

30 September 2017

1 reference

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From Na+/K+-ATPase and cardiac glycosides to cytotoxicity and cancer treatment

30 September 2017

1 reference

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Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Cinobufacini induced MDA-MB-231 cell apoptosis-associated cell cycle arrest and cytoskeleton function

30 September 2017

1 reference

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Cardiotonic steroids-mediated targeting of the Na(+)/K(+)-ATPase to combat chemoresistant cancers

30 September 2017

1 reference

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Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor

30 September 2017

1 reference

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Targeting the Na(+)/K(+)-ATPase alpha1 subunit of hepatoma HepG2 cell line to induce apoptosis and cell cycle arresting

30 September 2017

1 reference

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Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation

30 September 2017

1 reference

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Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis

30 September 2017

1 reference

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Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase

30 September 2017

1 reference

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Cinobufacini, an aqueous extract from Bufo bufo gargarizans Cantor, induces apoptosis through a mitochondria-mediated pathway in human hepatocellular carcinoma cells

30 September 2017

1 reference

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gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization

30 September 2017

1 reference

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Sorafenib in advanced hepatocellular carcinoma

30 September 2017

1 reference

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Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells

30 September 2017

1 reference

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The DNA damage response: ten years after

30 September 2017

1 reference

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DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action

30 September 2017

1 reference

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Regulation of Cdc25C activity during the meiotic G2/M transition.

30 September 2017

1 reference

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Cell cycle control, DNA damage checkpoints and cancer.

30 September 2017

1 reference

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Chk1 and Chk2 kinases in checkpoint control and cancer

30 September 2017

1 reference

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Chemical proteomics and its application to drug discovery

30 September 2017

1 reference

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QSAR evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/5(1).

30 September 2017

1 reference

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

30 September 2017

1 reference

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DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

30 September 2017

1 reference

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Distinct PKC isozymes regulate bufalin-induced differentiation and apoptosis in human monocytic cells

30 September 2017

1 reference

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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

30 September 2017

1 reference

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A long twentieth century of the cell cycle and beyond

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

The natural history of amphibian skin secretions, their normal functioning and potential medical applications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Treatment of U937 cells with bufalin induces the translocation of casein kinase 2 and modulates the activity of topoisomerase II prior to the induction of apoptosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Arenobufagin, a compound in toad venom, blocks Na(+)-K+ pump current in cardiac myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Taxol (paclitaxel): mechanisms of action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

The beta-carboline analog Mana-Hox causes mitotic aberration by interacting with DNA.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

p53 Promotes cell survival due to the reversibility of its cell-cycle checkpoints

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Discovery of bufadienolides as a novel class of ClC-3 chloride channel activators with antitumor activities.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

[Anti-angiogenetic effect of arenobufagin in vitro and in vivo].

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4741450

Depressive effects of arenobufagin on the delayed rectifier K+ current of guinea-pig cardiac myocytes

21 September 2018

1 reference

12 December 2020

Bufalin reduces the level of topoisomerase II in human leukemia cells and affects the cytotoxicity of anticancer drugs

1 reference

12 December 2020

Induction by bufalin of differentiation of human leukemia cells HL60, U937, and ML1 toward macrophage/monocyte-like cells and its potent synergistic effect on the differentiation of human leukemia cells in combination with other inducers

1 reference

12 December 2020

Arenobufagin, a bufadienolide compound from toad venom, inhibits VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway

1 reference

12 December 2020

Different conformations of double-stranded nucleic acid in solution as revealed by circular dichroism

1 reference

12 December 2020

Bufalin inhibits endothelial cell proliferation and angiogenesis in vitro

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.5545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26485758%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

26485758

1 reference