(Q36592129)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Munir Pirmohamed

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Leschziner GD

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Johnson MR

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

12 September 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

The Pharmacogenomics Journal

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

154-179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16969364%20AND%20SRC:MED&resulttype=core&format=json

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

30 December 2019

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

21 January 2018

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Impact of splice-site mutations of the human MDR1 cDNA on its stability and expression following retroviral gene transfer

21 January 2018

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Expression analysis of ABC transporters reveals differential functions of tandemly duplicated genes in Caenorhabditis elegans

21 January 2018

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

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MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

21 January 2018

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Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

21 January 2018

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Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

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Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

21 January 2018

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C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

21 January 2018

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Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms

21 January 2018

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Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

21 January 2018

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The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

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Common single nucleotide polymorphisms of the MDR1 gene have no influence on its mRNA expression level of normal kidney cortex and renal cell carcinoma in Japanese nephrectomized patients.

21 January 2018

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

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Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

21 January 2018

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Drug-drug interaction mediated by inhibition and induction of P-glycoprotein

21 January 2018

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Metabolism-based drug-drug interactions: what determines individual variability in cytochrome P450 induction?

21 January 2018

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Cardiomyocytes of chronically ischemic pig hearts express the MDR-1 gene-encoded P-glycoprotein.

21 January 2018

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MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

21 January 2018

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MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

21 January 2018

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Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

21 January 2018

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The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients

21 January 2018

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The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

21 January 2018

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Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

21 January 2018

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Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

21 January 2018

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MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.

21 January 2018

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C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects.

21 January 2018

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Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy

21 January 2018

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Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes

21 January 2018

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Amlodipine, but not MDR1 polymorphisms, alters the pharmacokinetics of cyclosporine A in Japanese kidney transplant recipients1

21 January 2018

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Whole-blood cultures from renal-transplant patients stimulated ex vivo show that the effects of cyclosporine on lymphocyte proliferation are related to P-glycoprotein expression

21 January 2018

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CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

21 January 2018

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MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients.

21 January 2018

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Sequential analysis of tacrolimus dosing in adult lung transplant patients with ABCB1 haplotypes

21 January 2018

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Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement

21 January 2018

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Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

21 January 2018

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No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects

21 January 2018

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MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes

21 January 2018

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Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia.

21 January 2018

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A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

21 January 2018

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Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

21 January 2018

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Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

21 January 2018

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Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo

21 January 2018

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Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2.

21 January 2018

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Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors.

21 January 2018

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Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism

21 January 2018

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P-glycoprotein drug transporter MDR1 gene polymorphism in renal transplant patients with and without gingival overgrowth

21 January 2018

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Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

21 January 2018

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ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation

21 January 2018

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A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

21 January 2018

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Investigation of polymorphism in the MDR1 gene and antidepressant-induced mania

21 January 2018

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Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

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An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children

21 January 2018

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Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

21 January 2018

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Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

21 January 2018

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Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics.

21 January 2018

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Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

21 January 2018

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HMG-CoA reductase inhibitors and P-glycoprotein modulation

21 January 2018

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Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner

21 January 2018

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The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia

21 January 2018

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An association study of 43 SNPs in 16 candidate genes with atorvastatin response

21 January 2018

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Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.

21 January 2018

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Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

21 January 2018

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Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia.

21 January 2018

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Population genetic structure of variable drug response

21 January 2018

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Use of unlinked genetic markers to detect population stratification in association studies.

21 January 2018

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Control of confounding of genetic associations in stratified populations

21 January 2018

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Testing for population subdivision and association in four case-control studies

21 January 2018

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Number of SNPS loci needed to detect population structure

21 January 2018

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Detecting association in a case-control study while correcting for population stratification

21 January 2018

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Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance

21 January 2018

1 reference

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Detecting multiple associations in genome-wide studies

21 January 2018

1 reference

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Statistical significance for genomewide studies

21 January 2018

1 reference

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Problems of reporting genetic associations with complex outcomes

21 January 2018

1 reference

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Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data

21 January 2018

1 reference

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A survey of current software for genetic power calculations

21 January 2018

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Carbamazepine is not a substrate for P-glycoprotein

21 January 2018

1 reference

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P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

21 January 2018

1 reference

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Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells

21 January 2018

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Association study designs for complex diseases

21 January 2018

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On the allelic spectrum of human disease

21 January 2018

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Genetics of complex disease: approaches, problems, and solutions

21 January 2018

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The future of genetic studies of complex human diseases

21 January 2018

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Epidemiological methods for studying genes and environmental factors in complex diseases

21 January 2018

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Logistic regression protects against population structure in genetic association studies

21 January 2018

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An utter refutation of the "fundamental theorem of the HapMap".

21 January 2018

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Digoxin pharmacokinetics and MDR1 genetic polymorphisms

21 January 2018

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Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

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The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

21 January 2018

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The barrier function of CYP3A4 and P-glycoprotein in the small bowel

21 January 2018

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7 January 2021

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells

1 reference

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7 January 2021

Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects

1 reference

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7 January 2021

Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities

1 reference

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7 January 2021

Intestinal inflammation induces adaptation of P-glycoprotein expression and activity

1 reference

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7 January 2021

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

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7 January 2021

MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects

1 reference

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7 January 2021

Guidelines for association studies in Human Molecular Genetics

1 reference

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7 January 2021

MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

Association of 5' CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

Identification of polymorphisms on the MDR1 gene among Turkish population and their effects on multidrug resistance in acute leukemia patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021

Linkage disequilibrium mapping of complex disease: fantasy or reality?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500413

7 January 2021