(Q36635237)

15 August 2017

title

Metabolism of thioamide antithyroid drugs (English)

1 reference

15 August 2017

Metabolism of Thioamide Antithyroid Drugs (English)

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

3 November 2022

author name string

Sitar DS

1

1 reference

15 August 2017

publication date

1 January 1990

1 reference

full work available at URL

15 August 2017

language of work or name

English

0 references

http://www.tandfonline.com/doi/pdf/10.3109/03602539008991448

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

3 November 2022

published in

Drug Metabolism Reviews

1 reference

15 August 2017

volume

22

1 reference

15 August 2017

issue

5

1 reference

15 August 2017

page(s)

477-502

1 reference

publication type of scholarly work

15 August 2017

review article

1 reference

Clinical Pharmacokinetics of Antithyroid Drugs

cites work

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Reduction in extrathyroidal triiodothyronine production by propylthiouracil in man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Metabolism of 35S-labelled antithyroid drugs in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Metabolism of thiopyrimidine derivatives: thiamylal, thiopental and thiouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

The pharmacology of substances affecting the thyroid gland

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

On the action and kinetics of propylthiouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

The absorption, distribution, excretion and metabolism of (2- 14 C)methimazole in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Excretion of propylthiouracil and its metabolites in rat bile and urine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Propylthiouracil Disposition in Older Hypothyroid Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Pharmacokinetics of methimazole in normal subjects and hyperthyroid patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

The pharmacokinetics of methimazole after oral administration of carbimazole and methimazole, in hyperthyroid patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Influence of Thyroid Dysfunction on Drug Pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

The acclumulation of 35 S-antithyroid drugs by the thyroid gland

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

35-S-antithyroid drug concentration and organic binding of iodine in the human thyroid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Serum protein binding of propylthiouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Biliary excretion of 35 S-labelled propylthiouracil, methimazole and carbimazole in untreated and pentobarbitone pretreated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Pharmacokinetic properties and bioavailability of methimazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Enzymic methylation of foreign sulfhydryl compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Purification and characterization of rat liver microsomal thiol methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Thiol S-methyltransferase from rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Glucuronide conjugation of 6-n-propyl-2-thiouracil and other antithyroid drugs by guinea pig liver microsomes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Site of glucuronide conjugation to the antithyroid drug 6-n-propyl-2-thiouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Oxidative Metabolites of [2-14C]Propylthiouracil in Rat Thyroid*

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Inhibition of hepatic mixed-function oxidase activity in vitro and in vivo by various thiono-sulfur-containing compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Identification of 3-methyl-2-thiohydantoin, a metabolite of carbimazole, in man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Enzymatic S-methylation of 6-n-propyl-2-thiouracil and other antithyroid drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

2-Mercapto-1-methyl-5-methylmercapto-imidazole: a new metabolite of thiamazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Drug metabolism in thyroid disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991448

Treatment of hyperthyroidism with propylthiouracil

21 January 2018

2

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

1-Methyl-2-mercaptoimidazole; an antithyroid compound highly active in man

3 November 2022

3

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Treatment of thyrotoxicosis with 2-carbethoxythio-1-methylglyoxaline (C.G.1)

3 November 2022

4

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Drug Metabolism and Disposition

3 November 2022

17

6

591

Lee P. W.

1978

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The metabolism of [2-14C]methimazole in the rat

3 November 2022

18

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Propylthiouracil and methimazole display contrasting pathways of peripheral metabolism in both rat and human

3 November 2022

19

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Metabolism of 35S- and 14C-labeled 1-methyl-2-mercaptoimidazole in vitro and in vivo

3 November 2022

20

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Pharmacokinetics of Propylthiouracil in Man After a Single Oral Dose

3 November 2022

23

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Improved method for the determination of methimazole in plasma by high-performance liquid chromatography

3 November 2022

24

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

High-performance Liquid Chromatographic Determination of Plasma Propylthiouracil

3 November 2022

25

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

High-pressure Liquid Chromatographic determination of Propylthiouracil in Human Plasma

3 November 2022

26

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Micro high-performance liquid chromatographic procedure for the quantitation of serum propylthiouracil

3 November 2022

27

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Determination of thiamazole in serum by high-performance liquid chromatography with electrochemical detection

3 November 2022

28

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Studies of propylthiouracil using a newly developed radioimmunoassay

3 November 2022

29

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Methimazole Pharmacology in the Rat: Studies Using a Newly Developed Radioimmunoassay for Methimazole*

3 November 2022

30

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Determination of methimazole in plasma using gas chromatography--mass spectrometry after extractive alkylation

3 November 2022

31

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The Pharmacokinetics of Propylthiouracil

3 November 2022

32

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The Kinetics of Propylthiouracil in Hyperthyroidism

3 November 2022

33

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Pharmacodynamics of Propylthiouracil in Normal and Hyperthyroid Subjects After a Single Oral Dose

3 November 2022

35

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Bioavailability of propylthiouracil: Interindividual variation and influence of food intake

3 November 2022

39

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Comparative In Vitro Effects and In Vivo Kinetics of Antithyroid Drugs

3 November 2022

42

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Altered disposition of propylthiouracil in cats with hyperthyroidism

3 November 2022

44

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Disposition of Intravenous Propylthiouracil

3 November 2022

45

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Propylthiouracil disposition in pregnant and post-partum women

3 November 2022

46

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The thyroid accumulation, oxidation and metabolic fate of 35 S-methimazole in the rat

3 November 2022

49

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Pharmacology & Therapeutics

3 November 2022

50

3

305

Marchant B.

1978

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Concentration of 35S-propylthiouracil by the thyroid gland and its relationship to anion trapping mechanism

3 November 2022

51

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The Placental Transfer of Propylthiouracil, Methimazole and Carbimazole

3 November 2022

54

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Accumulation of thiourylene antithyroid drugs in mouse salivary gland

3 November 2022

55

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Influence of sodium perchlorate on thiourylene antithyroid drug accumulation in mice

3 November 2022

56

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Effect of variations in acute and chronic iodine intake on the accumulation and metabolism of [35S]propylthiouracil by the rat thyroid gland

3 November 2022

57

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Effect of variations in acute and chronic iodine intake on the accumulation and metabolism of [35S]methimazole by the rat thyroid gland. Differences from [35S]propylthiouracil

3 November 2022

58

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Propylthiouracil in human milk. Revision of a dogma

3 November 2022

59

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Excretion of methimazole in human milk

3 November 2022

61

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Accumulation of 2-[14C]propylthiouracil in human polymorphonuclear leukocytes

3 November 2022

62

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The accumulation of [35S]methimazole by human and rat lymphocytes

3 November 2022

63

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The accumulation of [35S]methimazole by monocytes and macrophages

3 November 2022

64

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The relative toxicity of antithyroid drugs

3 November 2022

65

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Agranulocytosis secondary to methimazole therapy: report of two cases

3 November 2022

66

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Excretion of carbimazole and propylthiouracil in breast milk

3 November 2022

68

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Pharmacology of propylthiouracil (PTU) in pregnant hyperthyroid women: correlation of maternal PTU concentrations with cord serum thyroid function tests

3 November 2022

70

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Inhibition of hepatic glutathione transferases by propylthiouracil and its metabolites

3 November 2022

79

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Co-oxidation of arachidonic acid and methimazole by prostaglandin endoperoxide synthetase

3 November 2022

84

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

The role of porcine thyroid peroxidase and FAD-containing monooxygenase in the metabolism of 1-methyl-2-thioimidazole (methimazole)

3 November 2022

86

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Methimazole: its absorption and excretion in man and tissue distribution in rats

3 November 2022

87

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction

3 November 2022

89

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

Species differences in the alteration of drug-metabolizing activities of liver microsomes by thyroxine treatment

3 November 2022

90

1 reference

https://api.crossref.org/works/10.3109/03602539008991448

3 November 2022

Identifiers

1 reference

15 August 2017

1 reference