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Organ size control by Hippo and TOR pathways.
scientific article published on 7 May 2012
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Europe PubMed Central
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3601681
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1 February 2020
title
Organ size control by Hippo and TOR pathways
(English)
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Europe PubMed Central
PMCID
3601681
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1 February 2020
author
Ryan C Russell
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2
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Europe PubMed Central
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3601681
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1 February 2020
author name string
Karen Tumaneng
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1
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3601681
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1 February 2020
Kun-Liang Guan
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3
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3601681
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1 February 2020
language of work or name
English
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publication date
7 May 2012
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1 February 2020
published in
Current Biology
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3601681
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1 February 2020
volume
22
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Europe PubMed Central
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3601681
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1 February 2020
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R368-79
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1 February 2020
issue
9
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1 February 2020
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30 September 2017
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
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30 September 2017
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
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30 September 2017
The bantam microRNA is a target of the hippo tumor-suppressor pathway
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30 September 2017
The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila
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30 September 2017
Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1
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30 September 2017
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Functional genomics identifies TOR-regulated genes that control growth and division
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
From cell structure to transcription: Hippo forges a new path
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Drosophila target of rapamycin kinase functions as a multimer.
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PubMed Central
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30 September 2017
Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin
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PubMed Central
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30 September 2017
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Intestinal adaptation after massive intestinal resection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
TSC2 mediates cellular energy response to control cell growth and survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
retrieved
30 September 2017
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Drosophila Rheb GTPase is required for cell cycle progression and cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Akt regulates growth by directly phosphorylating Tsc2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
retrieved
30 September 2017
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The Rb/E2F pathway and cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The Hallmarks of Cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The role of c-myc in cellular growth control
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Size control in animal development
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
The regulation of E2F by pRB-family proteins
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Cell cycle checkpoints: preventing an identity crisis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
retrieved
30 September 2017
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
G1 phase progression: cycling on cue
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Inhibitors of mammalian G1 cyclin-dependent kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Differential mitotic rates and patterns of growth in compartments in the Drosophila wing
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Intrinsic and extrinsic control of growth in developing organs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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30 September 2017
Cooperative regulation of growth by Yorkie and Mad through bantam
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Coordination of growth and cell division in the Drosophila wing.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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28 June 2018
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Drosophila myc regulates organ size by inducing cell competition.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
A nutrient sensor mechanism controls Drosophila growth.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3601681
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5 September 2018
Role of retinoic acid in lens regeneration.
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PubMed Central
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5 September 2018
Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice.
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PubMed Central
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5 September 2018
Drosophila myc regulates cellular growth during development.
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5 September 2018
Drosophila S6 kinase: a regulator of cell size.
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PubMed Central
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5 September 2018
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.
1 reference
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PubMed Central
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5 September 2018
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.
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5 September 2018
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22575479
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
THE AUTONOMOUS BEHAVIOUR OF NORMAL THYMUS GRAFTS
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22575479
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RESTRICTED GROWTH CAPACITY OF MULTIPLE SPLEEN GRAFTS
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22575479
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22575479
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CUB.2012.03.003
1 reference
stated in
Europe PubMed Central
PMCID
3601681
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22575479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMCID
3601681
1 reference
stated in
Europe PubMed Central
PMCID
3601681
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22575479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed ID
22575479
1 reference
stated in
Europe PubMed Central
PMCID
3601681
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22575479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
ResearchGate publication ID
224938787
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