(Q36706939)

15 August 2017

1 reference

title

Telomere loss: mitotic clock or genetic time bomb? (English)

1 reference

15 August 2017

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

author name string

C. B. Harley

1

1 reference

PubMed ID

1722017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1722017

8 November 2022

language of work or name

English

0 references

publication date

1 March 1991

1 reference

PubMed ID

1722017

full work available at URL

15 August 2017

https://api.elsevier.com/content/article/PII:0921873491900187?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

https://api.elsevier.com/content/article/PII:0921873491900187?httpAccept=text/plain

8 November 2022

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

1 reference

15 August 2017

256

1 reference

15 August 2017

271-282

1 reference

15 August 2017

2-6

1 reference

The serial cultivation of human diploid cell strains

15 August 2017

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0014-4827(61)90192-6

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0014-4827(65)90211-9

Human telomeres contain at least three types of G-rich repeat distributed non-randomly

2

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Biomarkers of aging

4

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Chromosomal aberration and sister-chromatid exchange frequencies in peripheral blood lymphocytes of a large human population sample. II. Extension of age range

8 November 2022

5

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos

8 November 2022

6

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Progressive loss of DNA sequences from terminal chromosome deficiencies in Drosophila melanogaster

8 November 2022

7

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Chromosome ends in Drosophila without telomeric DNA sequences

8 November 2022

8

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Structure and function of telomeres

8 November 2022

9

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

The molecular structure of centromeres and telomeres

8 November 2022

10

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Molecular cloning of human telomeres in yeast.

8 November 2022

11

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Cellular senescence and DNA synthesis. Thymidine incorporation as a measure of population age in human diploid cells

8 November 2022

15

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Cloning of human telomeres by complementation in yeast

8 November 2022

16

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Doubling potential, calendar time, and senescence of human diploid cells in culture

8 November 2022

18

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Cell renewal in human epidermis

8 November 2022

19

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

The biology of aging

20

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Aging in vitro. Growth of cultured cells from the Galapagos tortoise.

8 November 2022

21

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Replicative senescence: the human fibroblast comes of age.

8 November 2022

22

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Senescence of cultured human fibroblasts: mitotic versus metabolic time.

8 November 2022

23

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Chronologic and Physiologic Age Affect Replicative Life-Span of Fibroblasts from Diabetic, Prediabetic, and Normal Donors

8 November 2022

24

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomeres, telomerase and senescence

8 November 2022

25

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Telomeres

26

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Telomerase is processive

27

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

8 November 2022

28

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

8 November 2022

29

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

8 November 2022

30

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Aging of cultured human skin fibroblasts

8 November 2022

32

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Cultured human fibroblasts: distribution of cell generations and a critical limit

8 November 2022

33

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Retesting the commitment theory of cellular aging.

8 November 2022

34

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomeres shorten during ageing of human fibroblasts

8 November 2022

35

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Checkpoints: controls that ensure the order of cell cycle events

8 November 2022

36

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomere reduction in human colorectal carcinoma and with ageing

8 November 2022

37

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Aging under glass

39

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs

8 November 2022

42

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Growth and death of diploid and transformed human fibroblasts

8 November 2022

43

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Hypervariable ultra-long telomeres in mice

8 November 2022

44

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Evolution and ageing

45

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Viable deletions of a telomere from a Drosophila chromosome.

8 November 2022

47

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomere end-replication problem and cell aging

8 November 2022

48

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

RNA-dependent polymerase motifs in EST1: tentative identification of a protein component of an essential yeast telomerase

8 November 2022

49

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

A mutant with a defect in telomere elongation leads to senescence in yeast

8 November 2022

50

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Conservation of the human telomere sequence (TTAGGG)n among vertebrates

8 November 2022

53

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

8 November 2022

54

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

8 November 2022

58

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Evidence for the recessive nature of cellular immortality

8 November 2022

59

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Recombination occurs during telomere formation in yeast

8 November 2022

61

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Epithelial stem cells in vivo

8 November 2022

62

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Growth of immortal simian virus 40 tsA-transformed human fibroblasts is temperature dependent

8 November 2022

63

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

8 November 2022

66

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers

8 November 2022

68

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Increased sensitivity of lymphocytes from people over 65 to cell cycle arrest and chromosomal damage.

8 November 2022

69

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Cellular senescence revisited: a review

8 November 2022

70

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Extensive telomere repeat arrays in mouse are hypervariable

8 November 2022

71

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells

8 November 2022

72

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

The role of limited cell replicative capacity in pathological age change. A review.

8 November 2022

74

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomere telomere recombination provides an express pathway for telomere acquisition

8 November 2022

75

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Origin of Concatemeric T7DNA

8 November 2022

76

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Pleiotropy, Natural Selection, and the Evolution of Senescence

8 November 2022

77

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Monovalent cation-induced structure of telomeric DNA: the G-quartet model

8 November 2022

78

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

EARLY CHROMOSOMAL CHANGES IN SV40-INFECTED HUMAN FIBROBLAST CULTURES

8 November 2022

79

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

8 November 2022

80

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.

8 November 2022

81

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Telomere terminal transferase activity in the hypotrichous ciliate Oxytricha nova and a model for replication of the ends of linear DNA molecules

8 November 2022

82

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

Structure and function of telomeres

8 November 2022

83

1 reference

https://api.crossref.org/works/10.1016/0921-8734(91)90018-7

8 November 2022

Identifiers

1 reference

15 August 2017

1 reference

PubMed ID

1722017