(Q36735003)

16 August 2017

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title

Metabonomics in pharmaceutical R&D. (English)

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16 August 2017

Jeremy K Nicholson

3

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Elaine Holmes

series ordinal

2

object named as

Elaine Holmes

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16 August 2017

John C Lindon

1

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16 August 2017

language of work or name

English

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publication date

1 March 2007

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16 August 2017

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16 August 2017

volume

274

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16 August 2017

issue

5

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16 August 2017

page(s)

1140-1151

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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

16 August 2017

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1 reference

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Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography

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An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers.

21 January 2018

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Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy

21 January 2018

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750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma

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Tissue targeted metabonomics: metabolic profiling by microdialysis sampling and microcoil NMR.

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Metabolomics – the link between genotypes and phenotypes

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Focused metabolomic profiling in the drug development process: advances from lipid profiling

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Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

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Orthogonal projections to latent structures (O-PLS)

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Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks

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NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats

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Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification

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Experimental metabonomic model of dietary variation and stress interactions

21 January 2018

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Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation

21 January 2018

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Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

21 January 2018

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Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

21 January 2018

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Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

21 January 2018

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The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

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21 January 2018

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Proton nuclear magnetic resonance-based metabonomics for rapid diagnosis of meningitis and ventriculitis

21 January 2018

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Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study

21 January 2018

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Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

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Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

21 January 2018

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Pharmaco-metabonomic phenotyping and personalized drug treatment

21 January 2018

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The challenges of modeling mammalian biocomplexity

21 January 2018

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Phenotype characterisation using integrated gene transcript, protein and metabolite profiling.

21 January 2018

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Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

21 January 2018

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Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis

21 January 2018

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NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach

21 January 2018

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21 January 2018

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Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis

21 January 2018

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21 January 2018

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Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

21 January 2018

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Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

21 January 2018

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Toxicological applications of magnetic resonance

21 January 2018

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Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’

21 January 2018

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NMR Spectroscopy of Biofluids

21 January 2018

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10.1111/J.1742-4658.2007.05673.X

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference