(Q36767504)

16 August 2017

1 reference

title

FOXP3 modifies the phenotypic and functional properties of regulatory T cells (English)

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16 August 2017

Daniel J Campbell

1

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PubMed ID

17380159

16 August 2017

Steven F Ziegler

series ordinal

2

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16 August 2017

1 April 2007

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Nature Reviews Immunology

16 August 2017

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16 August 2017

7

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16 August 2017

305-310

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16 August 2017

4

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Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor

16 August 2017

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Functional and molecular comparison of anergic and regulatory T lymphocytes

21 January 2018

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Scurfin (FoxP3) controls T-dependent immune responses in vivo through regulation of CD4+ T cell effector function

21 January 2018

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The amount of scurfin protein determines peripheral T cell number and responsiveness

21 January 2018

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IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

21 January 2018

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FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to nonlymphoid tissue homing receptors in secondary lymphoid tissues.

21 January 2018

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From vanilla to 28 flavors: multiple varieties of T regulatory cells

21 January 2018

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The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

31 March 2020

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Natural versus adaptive regulatory T cells

31 March 2020

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A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

31 March 2020

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Regulatory T cells: key controllers of immunologic self-tolerance

31 March 2020

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Regulatory T cells in autoimmmunity*.

31 March 2020

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

31 March 2020

1 reference

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

31 March 2020

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Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

31 March 2020

1 reference

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

31 March 2020

1 reference

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: a model of immune dysregulation

31 March 2020

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The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

31 March 2020

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Multiple Domains Define the Expression and Regulatory Properties of Foxp1 Forkhead Transcriptional Repressors

31 March 2020

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FOXP3 controls regulatory T cell function through cooperation with NFAT

31 March 2020

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Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

31 March 2020

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Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

31 March 2020

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FOXP3 ensembles in T-cell regulation

31 March 2020

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Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

31 March 2020

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Foxp3 occupancy and regulation of key target genes during T-cell stimulation

31 March 2020

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

31 March 2020

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Foxp3-dependent programme of regulatory T-cell differentiation

31 March 2020

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

31 March 2020

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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

31 March 2020

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Signal transmission between the plasma membrane and nucleus of T lymphocytes

31 March 2020

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Functional flexibility in T cells: independent regulation of CD4+ T cell proliferation and effector function in vivo

31 March 2020

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Interplay between TCR signalling and actin cytoskeleton dynamics.

31 March 2020

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All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton

31 March 2020

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CD4+CD25high regulatory cells in human peripheral blood

31 March 2020

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CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy

31 March 2020

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The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

31 March 2020

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Human CD4+CD25+ regulatory T cells

31 March 2020

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Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

31 March 2020

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

31 March 2020

1 reference

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

31 March 2020

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Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+CD25+ regulatory T cells

31 March 2020

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Altered proximal T cell receptor (TCR) signaling in human CD4+CD25+ regulatory T cells

31 March 2020

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Integration of T cell receptor-dependent signaling pathways by adapter proteins

31 March 2020

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Cytoskeletal remodeling in lymphocyte activation

31 March 2020

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Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

31 March 2020

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Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

31 March 2020

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

31 March 2020

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

31 March 2020

1 reference

31 March 2020

FOXP3: of mice and men.

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FOXP3: not just for regulatory T cells anymore

31 March 2020

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Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death

31 March 2020

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Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis

31 March 2020

1 reference

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

31 March 2020

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Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

31 March 2020

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Separable effector T cell populations specialized for B cell help or tissue inflammation

31 March 2020

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Rules of chemokine receptor association with T cell polarization in vivo

31 March 2020

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Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities☆

31 March 2020

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T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

31 March 2020

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Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

31 March 2020

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CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

31 March 2020

1 reference

Chemokines in lymphocyte trafficking and intestinal immunity

31 March 2020

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Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors.

31 March 2020

1 reference

A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection

31 March 2020

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Control of regulatory T cell development by the transcription factor Foxp3

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2061

1 reference

16 August 2017

1 reference

PubMed ID

17380159